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NADPH

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Identification
Molecular formula
C21H29N7O17P3
CAS number
53-57-6
IUPAC name
[[5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] (2,4-dihydroxy-3-methyl-3-phosphonooxy-butyl) hydrogen phosphate
State
State

At room temperature, NADPH exists as a solid powder. It is stable under normal conditions of temperature and pressure but may degrade upon exposure to light or extreme pH.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
745.43g/mol
Molar mass
745.4250g/mol
Density
1.1878g/cm3
Appearence

NADPH (Nicotinamide adenine dinucleotide phosphate) typically appears as a white to off-white, crystalline powder which is hygroscopic in nature, meaning it can absorb moisture from the environment. Its solubility in water makes it commonly used in aqueous solutions for biochemical applications.

Comment on solubility

Solubility of [5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] (2,4-dihydroxy-3-methyl-3-phosphonooxy-butyl) hydrogen phosphate

The solubility of the compound C21H29N7O17P3 can be intriguing due to its complex structure. Factors influencing the solubility of such compounds include:

  • Polarity: The presence of multiple functional groups like hydroxyls and phosphates generally enhances solubility in polar solvents, such as water.
  • Hydrogen Bonding: Compounds capable of forming hydrogen bonds tend to have higher solubility. This particular compound, with amine and hydroxyl groups, is expected to engage in hydrogen bonding with solvent molecules.
  • Hydrophilic vs. Hydrophobic Regions: The balance between hydrophilic (-OH and -PO4) and hydrophobic (carbon chains) regions can determine the overall solubility characteristics.

Moreover, it is essential to consider the following aspects:

  1. Solubility might vary with temperature—generally, higher temperatures increase solubility.
  2. The presence of salts in solution can either enhance or hinder solubility through common ion effects.
  3. pH levels can critically influence the ionization state of the compound, affecting its interaction with the solvent.

Overall, while one may hypothesize that this compound exhibits significant solubility in aqueous solutions due to its highly polar structure, empirical testing is recommended to provide definitive solubility data. As the wise adage goes, *“The proof of the pudding is in the eating.”*

Interesting facts

Interesting Facts about [5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl (2,4-dihydroxy-3-methyl-3-phosphonooxy-butyl) hydrogen phosphate

This compound, with its complex name, belongs to the family of phosphates, which are key players in biochemistry and molecular biology. Here are some fascinating aspects:

  • Structural Diversity: The molecule features a unique structure that includes several functional groups, such as amino, hydroxyl, and phosphoryl groups, reflecting its potential versatility in chemical reactions.
  • Biological Relevance: Phosphate compounds are essential in biological systems, especially in energy transfer (think ATP), signaling, and structural roles in nucleic acids, making this compound of particular interest to biochemists.
  • Potential Applications: Due to its intricate design, this compound may have applications in medicinal chemistry. Researchers are exploring its use as a pharmacological agent that could target specific pathways in cellular metabolism.
  • Interaction with Enzymes: Phosphorylation is a common mechanism for regulating proteins. This compound's ability to modify enzyme activity through phosphate group transfer could enable advancements in drug development.
  • Future Research Directions: Scientists are likely to investigate the biochemical interactions and possible therapeutic benefits of this compound, particularly in the realm of cancer research or as antiviral agents.

In conclusion, the compound's complex chemical nature and its implications in biological systems provide a rich area for research and exploration. As one might say in the lab, "the more we understand its structure, the more we can unlock its potential!"

Synonyms
PD043205