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Mephenytoin

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Identification
Molecular formula
C11H12ClN2O3
CAS number
50-12-4
IUPAC name
5-[(4-chlorophenoxy)methyl]-5-methyl-imidazolidine-2,4-dione
State
State
At room temperature, Mephenytoin exists as a solid. It is typically found in its crystalline form.
Melting point (Celsius)
129.00
Melting point (Kelvin)
402.00
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.00
General information
Molecular weight
218.68g/mol
Molar mass
218.6560g/mol
Density
1.3200g/cm3
Appearence

Mephenytoin is typically a white crystalline solid. It may also appear as a crystalline powder and has no significant odor.

Comment on solubility

Solubility of 5-[(4-chlorophenoxy)methyl]-5-methyl-imidazolidine-2,4-dione

The solubility of 5-[(4-chlorophenoxy)methyl]-5-methyl-imidazolidine-2,4-dione can be understood through a combination of its structural features and its interaction with various solvents. Here are some key points to consider:

  • Polarity: The presence of the 4-chlorophenoxy group suggests that the compound has varying polar characteristics, which could influence its solubility in polar versus non-polar solvents.
  • Hydrogen Bonding: The imidazolidine structure may allow for hydrogen bonding with water, potentially increasing solubility in aqueous conditions.
  • Solvent Compatibility: Generally, solubility is enhanced in solvents that share similar polarities with the solute. Therefore, it might be soluble in organic solvents like ethanol and dimethyl sulfoxide (DMSO).
  • Temperature: It’s essential to note that the solubility can greatly increase with temperature; heating the solvent can lead to greater solvation of the compound.

In summary, while the exact solubility of 5-[(4-chlorophenoxy)methyl]-5-methyl-imidazolidine-2,4-dione in different solvents isn't explicitly defined, its structural characteristics indicate a potential for solubility in both polar and non-polar environments. Experimentation is advised to find optimal conditions for practical applications.

Interesting facts

Interesting Facts about 5-[(4-chlorophenoxy)methyl]-5-methyl-imidazolidine-2,4-dione

5-[(4-chlorophenoxy)methyl]-5-methyl-imidazolidine-2,4-dione, often referred to as a potential pharmaceutical compound, is part of a larger class of imidazolidine derivatives. These compounds have gained attention in medicinal chemistry due to their unique structural attributes and biological activities. Here are some fascinating aspects:

  • Peculiar Structure: The presence of both a chlorophenyl group and a dione functional group makes this compound a significant point of study for structural–activity relationships (SAR) in drug design.
  • Biological Activity: Compounds in this class have displayed a range of biological activities, including anti-inflammatory, antioxidant, and possible antitumor properties, making them candidates for various therapeutic uses.
  • Synthetic Applications: The synthesis of imidazolidine derivatives often involves intricate methods, with the potential for modifying substituents to enhance efficacy and reduce toxicity.
  • Research Potential: As scientists continue to explore the mechanisms of action, 5-[(4-chlorophenoxy)methyl]-5-methyl-imidazolidine-2,4-dione could pave the way for new discoveries in both chemistry and pharmacology.
  • Interdisciplinary Interest: This compound intrigues chemists, biologists, and pharmacologists alike, showcasing the importance of collaboration across disciplines to unlock its full potential.

In summary, 5-[(4-chlorophenoxy)methyl]-5-methyl-imidazolidine-2,4-dione represents a compelling subject of study within the realm of medicinal chemistry, holding promise for future research and the development of novel therapeutics. As a scientist, one may find it enthralling to delve deeper into its properties and applications.

Synonyms
BRN 0800325
5-((p-Chlorophenoxy)methyl)-5-methylhydantoin
4579-59-3
p-Chlorophenoxymethyl-5 methyl-4 hydantoine [French]
HYDANTOIN, 5-((p-CHLOROPHENOXY)METHYL)-5-METHYL-
p-Chlorophenoxymethyl-5 methyl-4 hydantoine
2,4-Imidazolidinedione, 5-((4-chlorophenoxy)methyl)-5-methyl-
5-25-02-00405 (Beilstein Handbook Reference)
DTXSID20963441
4-[(4-Chlorophenoxy)methyl]-4-methyl-4H-imidazole-2,5-diol