Skip to main content

CET-0092

ADVERTISEMENT
Identification
Molecular formula
C17H13ClN2O
CAS number
2458-94-8
IUPAC name
5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol
State
State
The compound is typically a solid at room temperature, appearing as a white crystalline substance.
Melting point (Celsius)
219.00
Melting point (Kelvin)
492.15
Boiling point (Celsius)
700.00
Boiling point (Kelvin)
973.15
General information
Molecular weight
300.78g/mol
Molar mass
300.7790g/mol
Density
1.5461g/cm3
Appearence

This compound is a solid and typically appears as a white to off-white crystalline powder. It may exhibit moderate to low solubility in water and organic solvents depending on its polymorphic form.

Comment on solubility

Solubility of 5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol: C17H13ClN2O

The solubility of 5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol can be quite intriguing due to its complex structure. Here are some key points to consider:

  • Polarity: The presence of the chlorophenyl group and hydroxyl group suggests moderate polarity, which may improve solubility in polar solvents.
  • Solvent Interaction: This compound is likely to exhibit varying solubility in different solvents, commonly being soluble in:
    • Dimethyl sulfoxide (DMSO)
    • Ethanol
    • Aqueous solutions, to some extent
  • Limitations: On the contrary, solubility might be limited in non-polar solvents such as:
    • Hexane
    • Chloroform

As a general rule, compounds with similar structures tend to show some level of solubility in polar solvents but may struggle to dissolve in non-polar environments. This behavior is a crucial factor for applications in pharmaceuticals and chemical industries where solubility influences overall effectiveness.

In conclusion, while 5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol's solubility can be assessed, definitive empirical data is essential for precise applications.

Interesting facts

Interesting Facts about 5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol

The compound 5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol is an intriguing member of the isoindole family, known for its complex structure and potential therapeutic applications.

Key Features:

  • Unique Structure: This compound features a fused imidazole and isoindole framework, providing it with unique chemical reactivity and biological properties.
  • Pharmacological Potential: Research indicates that compounds containing the imidazo structure may exhibit promising pharmacological activities, including anti-inflammatory and anti-cancer properties.
  • Chlorination Impact: The presence of the 4-chlorophenyl group enhances the compound's lipophilicity, potentially influencing its interaction with biological targets and improving its efficacy as a drug candidate.
  • Synthesis Challenge: The synthesis of such complex compounds often requires innovative methodologies, highlighting the significance of synthetic organic chemistry in developing new medicinal agents.

As a scientist or student venturing into the field of medicinal chemistry, exploring the implications of this compound can lead to exciting discoveries. The blend of traditional organic chemistry with modern pharmacological insights makes 5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol a captivating subject for research and study.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." Studying such multifaceted compounds can inspire innovative thoughts and groundbreaking research in the quest for new therapeutic agents.

Synonyms
mazindol
Mazanor
Sanorex
22232-71-9
Mazildene
Magrilon
Teronac
Dimagrir
Terenac
Mazindole
Mazindolum
Mazindolum [INN-Latin]
AN 448
Mazindol civ
SAH 42548
5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol
AN-448
CCRIS 3152
HSDB 3112
SaH-42548
SA 42-548
5-(4-Chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol
EINECS 244-857-0
UNII-C56709M5NH
BRN 0546547
5-p-Chlorophenyl-2,3-dihydro-5H-imidazo(2,1-a)isoindol-5-ol
3H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,5-dihydro-
5-(4-Chlorophenyl)-2,3-dihydro-5-hydroxy-5H-imidazo[2,1-a]isoindole
C56709M5NH
CHEMBL781
5-(4-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
5-(p-Chlorophenyl)-2,5-dihydro-3H-imidazo(2,1-a)isoindol-5-ol
5H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,3-dihydro
5-(4-Chlorophenyl)-2,3-dihydro-5-hydroxy-5H-imidazo(2,1-a)isoindole
DTXSID1023237
Mazindol [USAN:USP:INN:BAN]
3H-Imidazo(2,1-a)isoindol-5-ol, 2,5-dihydro-5-(4-chlorophenyl)-
3H-Imidazo(2,1-a)isoindol-5-ol, 5-(p-chlorophenyl)-2,5-dihydro-
3H-Imidazo[2,1-a]isoindol-5-ol, 5-(4-chlorophenyl)-2,5-dihydro-
Mazindolum (INN-Latin)
MAZINDOL (MART.)
MAZINDOL [MART.]
MAZINDOL (USP IMPURITY)
MAZINDOL [USP IMPURITY]
Mazindol (USAN:USP:INN:BAN)
5-(4-chlorophenyl)-2H,3H,5H-imidazo[2,1-a]isoindol-5-ol
Mazindol (1mg/ml in Acetonitrile)
Mazindol (1.0 mg/mL in Methanol)
3H-Imidazo[2,1-a]isoindol-5-ol, 5-(p-chlorophenyl)-2,5-dihydro-
(+/-)-5-(P-CHLOROPHENYL)-2,5-DIHYDRO-3H-IMIDAZO(2,1-A)ISOINDOL-5-OL
3H-IMIDAZO(2,1-A)ISOINDOL-5-OL, 5-(4-CHLOROPHENYL)-2,5-DIHYDRO-, (+/-)-
[3H]-mazindol
DEA No. 1605
[3H]MAZINDOL
SANOREX (TN)
S 42548
Mazindol (JAN/USP/INN)
Mazindolo
5-(p-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
Mazindol; 5-(4-Chlorophenyl)-2,5-dihydro-3H-imidazol[2,1-a]isoindol-5-ol; 5-(4-Chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol
MAZINDOL [HSDB]
MAZINDOL [USAN]
MAZINDOL [INN]
MAZINDOL [JAN]
MAZINDOL [MI]
MAZINDOL [VANDF]
(+-)-5-(p-Chlorophenyl)-2,5-dihydro-3H-imidazo(2,1-a)isoindol-5-ol
Mazindol, 1mg/ml in Dmf
MAZINDOL [WHO-DD]
SCHEMBL27849
MLS003899228
MAZINDOL [ORANGE BOOK]
CHEBI:6702
DTXCID403237
GTPL4591
GTPL4797
A08AA05
WZB81550
Mazindol, >=98% (TLC), powder
BDBM50005536
MFCD00864480
3H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,5-dihydro-, (+-)-
AKOS015895573
DB00579
NCGC00378886-01
FM156784
HY-15279
SMR000238174
NS00003468
5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo
D00367
A816031
Q255680
BRD-A68464583-001-02-5
5-(4-CHLOROPHENYL)-2,3-DIHYDRO-5-HYDROXY-5H-IMIDAZO
Mazindol, United States Pharmacopeia (USP) Reference Standard
5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
5-(4-chlorophenyl)-2,3-dihydro-5H-imidazo [2,1-a]isoindol-5-ol
5-(4-chlorophenyl)-2,3-dihydro-5H-imidazo[2,1-a]isoindol-5-ol
5-(4-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol #
5H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,3-dihydro-
5-Thiophen-2-yl-2,3,5,6-tetrahydro-imidazo[2,1-a]isoquinolin-5-ol
244-857-0