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Identification
Molecular formula
C18H21NO4S
CAS number
Not available
IUPAC name
5-(4-isopropylsulfonylphenyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline
State
State

At room temperature, the compound exists as a solid substance, possibly forming crystalline structures.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
510.00
Boiling point (Kelvin)
783.15
General information
Molecular weight
347.41g/mol
Molar mass
347.4130g/mol
Density
1.3000g/cm3
Appearence

The compound is typically a crystalline solid with a color that may range from white to off-white.

Comment on solubility

Solubility of 5-(4-isopropylsulfonylphenyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline

The solubility of 5-(4-isopropylsulfonylphenyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline is influenced by several factors due to its complex structure. Here are some key points regarding its solubility:

  • Polarity: The presence of the isopropyl sulfonyl group significantly affects polarity, which could enhance solubility in polar solvents.
  • Solvent Compatibility: Likely soluble in dimethyl sulfoxide (DMSO) and possibly ethanol, yet limited solubility in non-polar solvents.
  • pH Sensitivity: Solubility can vary with pH; ionization of functional groups at different pH levels may lead to increased solubility.
  • Temperature Effect: Higher temperatures generally increase solubility, so dissolution might improve with an increase in temperature.

In conclusion, while the solubility profile of this compound is somewhat complex, understanding its interaction with various solvents gives insight into its practical applications in chemical and pharmaceutical fields.

Interesting facts

Exploring 5-(4-isopropylsulfonylphenyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline

This fascinating compound, 5-(4-isopropylsulfonylphenyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline, is a member of the isoquinoline class, which is known for its intricate ring structures and diverse biological activity. Here are some insights about this intriguing compound:

  • Medicinal Potential: Isoquinolines have a rich history in medicinal chemistry. They are often studied for their potential in treating a variety of ailments, including neurological disorders, as some exhibit neuroprotective properties.
  • Structural Complexity: The presence of a dioxole moiety and sulfonyl group enhances the structural complexity of this compound, which may contribute to interesting interactions at the molecular level.
  • Research Interest: The unique combination of substituents in this isoquinoline derivative has made it a subject of interest in research, particularly in the development of new pharmaceuticals.
  • Customizable Chemistry: The isopropylsulfonyl group allows for innovative approaches to modifying the compound to enhance its properties, such as increasing solubility or specificity towards biological targets.

As we dive into the world of organic chemistry, compounds like this one showcase the balance between structure and function that chemists strive to understand. “Every new structure tells a story,” as a famous chemist once said, and indeed, this compound may be a chapter in the ongoing narrative of drug discovery and development.

Synonyms
20884-95-1
BRN 1604858
5,6,7,8-Tetrahydro-5-(p-(isopropylsulfonyl)phenyl)-1,3-dioxolo(4,5-g)isoquinoline
1,2,3,4-Tetrahydro-1-(p-(isopropylsulfonyl)phenyl)-6,7-methylenedioxyisoquinoline
1,3-Dioxolo(4,5-g)isoquinoline, 5,6,7,8-tetrahydro-5-(p-(isopropylsulfonyl)phenyl)-
RefChem:219020
DTXSID80943148
5,6,7,8-Tetrahydro-5-[4-(isopropylsulfonyl)phenyl]-1,3-dioxolo[4,5-g]isoquinoline
5-[4-(Propane-2-sulfonyl)phenyl]-5,6,7,8-tetrahydro-2H-[1,3]dioxolo[4,5-g]isoquinoline