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Pridopidine hydrochloride

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Identification
Molecular formula
C22H26ClNO4S
CAS number
346688-38-8
IUPAC name
5-(4-isopropylsulfonylphenyl)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride
State
State

Pridopidine hydrochloride is typically a solid under standard conditions of temperature and pressure. In pharmaceutical formulations, it is generally found as a stable solid.

Melting point (Celsius)
257.00
Melting point (Kelvin)
530.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
423.97g/mol
Molar mass
423.9600g/mol
Density
1.3400g/cm3
Appearence

Pridopidine hydrochloride typically appears as a white to off-white crystalline powder. Its fine particulate nature often poses a soft texture depending on crystal size. The compound may exhibit hygroscopic properties under certain conditions.

Comment on solubility

Solubility of 5-(4-isopropylsulfonylphenyl)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

The solubility of 5-(4-isopropylsulfonylphenyl)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride is influenced by various factors inherent to its chemical structure. Understanding the solubility characteristics of this compound can provide valuable insights into its reactivity and potential applications. Below are some key aspects to consider:

  • Polarity: The presence of the isopropylsulfonyl group likely contributes to polar characteristics, which can increase solubility in polar solvents.
  • Chloride Ion: The inclusion of the chloride counterion might enhance solubility in water and other aqueous solutions.
  • Hydrophobic Regions: The bulky isopropyl group may create hydrophobic areas, affecting solubility in non-polar solvents.
  • pH Dependence: The solubility may vary with pH, as ionic forms could exhibit different solubility behaviors depending on the environmental acidity or alkalinity.

In summary, the solubility of this compound is a complex interplay of its structural components and environmental conditions. It’s important to experimentally determine the solubility in specific solvents to evaluate its practical applications fully. As with many tailored chemical compounds, one can never overlook the impact of molecular design on solubility characteristics!

Interesting facts

Interesting Facts about 5-(4-isopropylsulfonylphenyl)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

This unique compound, often referred to by its systematic name, showcases the fascinating interplay of structure and function in organic chemistry. It is a member of the isoquinoline family and is characterized by a complex tetrahydro-dioxolo structure that includes both aromatic and aliphatic elements, making it a subject of interest for various fields.

Chemical Properties and Applications

The presence of the isopropylsulfonyl group significantly contributes to the compound's behavior and interactions. Here are some noteworthy aspects:

  • Pharmaceutical Potential: Compounds like this are often studied for their medicinal properties, particularly in the realm of neuropharmacology due to their capacity to interact with biological receptors.
  • Structural Diversity: The unique arrangement of the dioxolo and isoquinoline moieties provides a rich canvas for the development of derivatives with modified pharmacological profiles.
  • Synthetic Challenges: The complexity of synthesizing such a compound allows for the exploration of various synthetic methodologies, including multi-step reactions and catalysis.

Research Insights

Researchers have been investigating the biochemical pathways influenced by this chemical. Here are a few insights:

  • Studies show that this compound can exhibit selective anti-inflammatory properties, potentially making it a lead candidate for developing treatments for chronic inflammatory diseases.
  • Its unique structure allows it to serve as a versatile scaffold for chemical modifications, leading to a library of derivatives.
  • Spectroscopic techniques, such as NMR and mass spectrometry, play a critical role in elucidating the intricate features of its molecular configuration.

In conclusion, 5-(4-isopropylsulfonylphenyl)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride offers a realm of possibilities in both academic research and industrial applications. The combination of its structural complexity and potential pharmacological applications makes it an exciting subject in the field of organic chemistry.

Synonyms
20884-96-2
1,3-Dioxolo(4,5-g)isoquinoline, 5,6,7,8-tetrahydro-5-(p-(isopropylsulfonyl)phenyl)-6-methyl-, hydrochloride
RefChem:219021