Mirtazapine | Solubility of Things

Identification

Molecular formula

C₁₇H₁₉N₃

CAS number

61337-67-5

IUPAC name

5-(4H-imidazol-2-ylmethyl)-6,11-dihydrobenzo[c][1]benzazepine

State

At room temperature, Mirtazapine is in a solid state.

Melting point (Celsius)

114.50

Melting point (Kelvin)

387.70

Boiling point (Celsius)

529.10

Boiling point (Kelvin)

802.30

General information

Molecular weight

265.36g/mol

Molar mass

265.3620g/mol

Density

1.3000g/cm³

Appearence

Mirtazapine is typically found as a white to creamy-white crystalline powder.

Comment on solubility

Solubility of 5-(4H-imidazol-2-ylmethyl)-6,11-dihydrobenzo[c][1]benzazepine

The solubility of 5-(4H-imidazol-2-ylmethyl)-6,11-dihydrobenzo[c][1]benzazepine can be quite complex due to its unique molecular structure, which influences its interaction with solvents.

Considerations for Solubility:

Polarity: The solubility of this compound may be affected by the presence of polar and non-polar regions within its structure, impacting its solubility in various solvents.
Hydrogen Bonding: The imidazole group can form hydrogen bonds, which may enhance solubility in polar solvents, particularly those that can donate or accept hydrogen bonds.
Molecular Size: The larger size of the benzo[c][1]benzazepine framework could limit its solubility compared to smaller compounds.
Temperature Effects: As with many organic compounds, increasing temperature typically enhances solubility, which is a factor to consider during experiments.

In practice, when evaluating solubility, it may be beneficial to conduct empirical solubility tests in various solvents, including water, ethanol, and DMSO, to ascertain its behavior in different environments. Therefore, understanding the solubility of 5-(4H-imidazol-2-ylmethyl)-6,11-dihydrobenzo[c][1]benzazepine is pivotal for its applications in pharmaceuticals and other chemical fields.

Interesting facts

Interesting Facts about 5-(4H-imidazol-2-ylmethyl)-6,11-dihydrobenzo[c][1]benzazepine

The compound 5-(4H-imidazol-2-ylmethyl)-6,11-dihydrobenzo[c][1]benzazepine is a fascinating molecule that highlights the intersection of organic chemistry and medicinal design. Here are some intriguing aspects of this compound:

Complex Structure: This compound features a multifunctional heterocyclic architecture, integrating both imidazole and benzazepine moieties. This complex structure may contribute to its biological activity, making it a subject of interest in drug development.
Biological Relevance: Compounds of this nature are often explored for their potential roles in medicinal chemistry. Their structures can be tailored to target specific biological pathways, making them possible candidates for treating various diseases, including cancer and neurological disorders.
Imidazole Functionality: The imidazole ring is noted for its significance in biochemistry. It acts as a biological nucleophile and is present in various enzymes, suggesting that the presence of an imidazole substitution could enhance the compound's interaction with biological targets.
Research Applications: Ongoing studies may focus on understanding the pharmacokinetics and the mechanism of action of this compound, contributing valuable knowledge to the field of medicinal chemistry.
Structure-Activity Relationship (SAR): The intricate interplay between the structure and activity of this compound provides a rich area for research, allowing chemists to explore how modifications can influence its efficacy and selectivity.

In conclusion, 5-(4H-imidazol-2-ylmethyl)-6,11-dihydrobenzo[c][1]benzazepine serves as a compelling example of how complex organic compounds can be harnessed for potential therapeutic applications. As researchers continue to explore its properties, it could pave the way for novel treatments in various medical fields.