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Folinic Acid

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Identification
Molecular formula
C20H23N7O6
CAS number
58-05-9
IUPAC name
[5-[5-[4-(3-amino-6,7-dimethyl-1-oxo-4,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)phenyl]-2,3,4-trihydroxy-pentoxy]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl 1,3-dicarboxypropyl phosphate
State
State

Total ionizes as a solid at room temperature.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.15
Boiling point (Celsius)
606.00
Boiling point (Kelvin)
879.15
General information
Molecular weight
474.45g/mol
Molar mass
474.4510g/mol
Density
1.5800g/cm3
Appearence

Folinic acid typically appears as a white to light yellow crystalline powder. Due to its chemical nature and purity, its appearance may vary slightly, with some exhibiting more of a slight yellow hue, an indication of degradation or impurity in the sample.

Comment on solubility

Solubility of 5-[5-[4-(3-amino-6,7-dimethyl-1-oxo-4,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)phenyl]-2,3,4-trihydroxy-pentoxy]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl 1,3-dicarboxypropyl phosphate (C20H23N7O6)

The solubility profile of this intricate compound offers insights into its potential applications and biological interactions. Here are key points regarding its solubility:

  • Water Solubility: Given its complex structure and the presence of multiple hydroxyl groups, which are polar in nature, the compound may exhibit enhanced solubility in water. The hydroxyl groups can form hydrogen bonds with water molecules, improving its aqueous solubility.
  • Solvent Compatibility: The presence of hydrophobic segments within the structure suggests that the compound may also dissolve in organic solvents, such as ethanol and DMSO. This dual solubility characteristic can be advantageous for various applications, including drug delivery systems.
  • pH Dependence: Solubility may vary significantly with pH. At acidic or basic conditions, protonation or deprotonation of functional groups may enhance solubility, making them more or less hydrophilic.
  • Temperature Influence: As is common with many chemical compounds, an increase in temperature typically enhances solubility. Thus, using temperature-adjusted conditions may be beneficial for experimental applications.

In summary, the intricate balance between hydrophilic and hydrophobic characteristics suggests that C20H23N7O6 may be soluble in both aqueous and organic solvents, depending on external conditions such as pH and temperature. Understanding these solubility factors can aid researchers in harnessing the full potential of this compound in various chemical and biological contexts.

Interesting facts

Interesting Facts about 5-[5-[4-(3-amino-6,7-dimethyl-1-oxo-4,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)phenyl]-2,3,4-trihydroxy-pentoxy]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl 1,3-dicarboxypropyl phosphate

This compound is a fascinating example of complex organic chemistry, showcasing the intricate nature of molecular architectures in drug design and bioactive molecules. Here are some noteworthy aspects:

  • Structure Complexity: The compound features a multi-layered structure that includes a pteridine moiety, which is essential in numerous biological processes, including those involving nucleic acids and cellular functions.
  • Potential Biological Activity: Given its component of amino groups, hydroxyl groups, and phosphate functionality, this compound may exhibit a range of biological activities, potentially involving cell signaling pathways.
  • Applications in Medicine: With its diverse functional groups, the compound could be explored for therapeutic applications, particularly in the field of cancer research and treatment, possibly acting in ways that inhibit or alter cellular proliferation.
  • Interconnectedness in Chemistry: The relationship between organic and medicinal chemistry is highlighted in this structure, as it exhibits features that are tailor-suited to interact with biological targets.
  • Research Potential: Scientists are continuously looking for compounds like this to serve as templates for drug development, focusing on optimizing their effectiveness and minimizing side effects.

Considering its design, every component of this compound is a testament to the intricate web of interactions that define pharmacology and biochemistry. As one researcher aptly noted, "Understanding these compounds opens doors to new paradigms in drug discovery."

This compound exemplifies the pivotal role that detailed structural knowledge plays in advancing our understanding and application of chemical compounds in therapeutic settings.