Skip to main content

Thiamine disulfide

ADVERTISEMENT
Identification
Molecular formula
C24H34N4O4S2
CAS number
67-40-1
IUPAC name
5-[[[5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridyl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methyl-pyridin-3-ol
State
State

Thiamine disulfide is typically in a solid state at room temperature due to its high melting point. It may be found in various preparations and can be used in solid dosage forms such as tablets and capsules.

Melting point (Celsius)
248.00
Melting point (Kelvin)
521.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
278.35g/mol
Molar mass
278.3490g/mol
Density
1.3785g/cm3
Appearence

Thiamine disulfide, also known as vitamin B1 disulfide, typically appears as an off-white or yellowish crystalline powder. It may also appear granular depending on the preparation. It is sensitive to light, which may cause discoloration. The compound has a slight odor characteristic of sulfur compounds.

Comment on solubility

Solubility of 5-[[[5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridyl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methyl-pyridin-3-ol

The solubility of complex organic compounds like 5-[[[5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridyl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methyl-pyridin-3-ol can be highly variable and warrants a detailed understanding. This compound contains multiple functional groups, which can influence its interaction with solvents.

Factors Influencing Solubility

  • Polarity: The presence of hydroxyl (-OH) groups can enhance solubility in polar solvents, while hydrophobic regions may limit solubility in water.
  • Hydrogen Bonding: The ability to form hydrogen bonds can significantly increase solubility, especially in water or alcohols.
  • Temperature: Generally, solubility increases with temperature for solid solutes.
  • pH Levels: Changes in pH can affect the ionization of functional groups, thus influencing solubility.

In summary, while the solubility of this particular compound in water may be limited due to its complex structure, it could be more soluble in organic solvents such as DMSO or ethanol due to its functional groups. As noted, "each compound has its own unique solubility profile, shaped by its functional groups and molecular interactions." Thus, empirical solubility tests are essential for a precise understanding of this compound's behavior in various solvents.

Interesting facts

Interesting Facts about 5-[[[5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridyl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methyl-pyridin-3-ol

This complex organic compound, often referred to as an advanced pyridine derivative, exemplifies the fascinating world of organic chemistry through its unique structural features and potential applications.

Structural Complexity

The compound showcases a multifaceted structure comprised of:

  • Pyridine rings: These are heterocyclic aromatic compounds that contribute to the stability and reactivity of the material.
  • Disulfane group: The presence of the disulfanyl group introduces reactivity associated with sulfur, which can be crucial in biological and chemical processes.
  • Hydroxymethyl groups: These functionalities are known to enhance solubility and reactivity, making the compound versatile in different environments.

Potential Applications

This compound's intricate structure holds promise across various fields:

  • Pharmaceutical development: Compounds with pyridine structures are often found in pharmaceutical agents, presenting opportunities for novel drug synthesis.
  • Catalysis: The unique electronic properties offered by this compound could lead to the development of new catalytic processes.
  • Material science: The stability of such compounds can lend themselves to advancements in materials that require specific chemical properties.

Key Takeaway

As one delves into the realm of complex organic compounds, this pyridine derivative serves as a remarkable example of how structural intricacies can lead to a myriad of functional properties, positioning it as a compound of high scientific interest. With a carefully tuned structure, it has the potential to unlock innovations in various scientific disciplines.

Synonyms
PYRITINOL
Pyrithioxin
Pyrithioxine
Encefabol
Bonol
Pyridoxine disulfide
Vitamin B6 disulfide
Pyritioxine
Pyridoxine-5-disulfide
Piritinolo [DCIT]
Pyritinolum
Piritinolo
Piritinol [INN-Spanish]
Pyritinolum [INN-Latin]
Pyrithioxine [JAN]
Pyritinol [INN:BAN:DCF]
UNII-AK5Q5FZH2R
EINECS 214-150-1
Pyritinol (INN)
4-Pyridinemethanol, 3,3'-[dithiobis(methylene)]bis[5-hydroxy-6-methyl-
NSC-759229
Pyrithioxine (JAN)
Pyritinol HCl
PYRITINOL [INN]
PYRITINOL [MI]
PYRITINOL [WHO-DD]
Pyritinol Hydrochloride
DTXSID3048362
4-Pyridinemethanol, 3,3'-(dithiodimethylene)bis(5-hydroxy-6-methyl-
3,3'-(Dithiobis(methylene))bis(5-hydroxy-6-methyl-4-pyridinemethanol)
NSC 759229
Piritinol (INN-Spanish)
Pyritinolum (INN-Latin)
4-Pyridinemethanol, 3,3'-(dithiobis(methylene))bis(5-hydroxy-6-methyl-
ENBOL
Pyridoxinedisulfide
PYRITINOL HYDROCHLORIDE (MART.)
PYRITINOL HYDROCHLORIDE [MART.]
PYRITINOL HYDROCHLORIDE [WHO-DD]
PYRITINOL DIHYDROCHLORIDE MONOHYDRATE [MI]
5-((((5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl)methyl)disulfanyl)methyl)-4-(hydroxymethyl)-2-methylpyridin-3-ol
5-[({[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyl}disulfanyl)methyl]-4-(hydroxymethyl)-2-methylpyridin-3-ol
DTXCID9028336
N06BX02
4-Pyridinemethanol, 3,3'-(dithiobis(methylene))bis(5-hydroxy-6-methyl-)
214-150-1
1098-97-1
Piritinol
Epocan
Dipyridoxolyldisulfide
Biocefalin
5,5'-(Disulfanediylbis(methylene))bis(4-(hydroxymethyl)-2-methylpyridin-3-ol)
AK5Q5FZH2R
5-[[[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methylpyridin-3-ol
5,5'-[Dithiobis(methylene)]bis[4-(hydroxymethyl)-2-methylpyridin-3-ol]
NCGC00166140-01
5,5'-(disulfanediyldimethanediyl)bis[4-(hydroxymethyl)-2-methylpyridin-3-ol]
MFCD00151477
PYRITINOL, Pyrithioxin
MLS004712044
SCHEMBL150551
CHEMBL488093
Pyrithioxin, analytical standard
CHEBI:135554
HMS3264M15
HMS3886M13
Pharmakon1600-01505762
HY-B0910
3,3'-(Dithiodimethylene)bis(5-hydroxy-6-methyl-4-pyridinemethanol)
BBL028281
NSC759229
s5141
STK801801
AKOS005066380
CCG-213980
DB13084
5-[[[5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridyl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methyl-pyridin-3-ol
AC-12193
AS-13595
SMR001550535
SBI-0207045.P001
DB-050233
NS00010168
P2250
C71346
D02160
AB00375835_02
Q416361
SR-01000872772
SR-01000872772-1
BRD-K82181219-001-01-9
BRD-K82181219-001-04-3
Bis(4-hydroxymethyl-5-hydroxy-6-methyl-3-pyridylmethyl)disulfide
5,5'-(dithiodimethylene) bis[3-hydroxy-4-hydroxymethyl-2-methylpyridine]
5,5'-(dithiodimethylene)bis[3-hydroxy-4-hydroxymethyl-2-methylpyridine]