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Nithiazide

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Identification
Molecular formula
C7H8N2O3SH2
CAS number
139-65-1
IUPAC name
[5-(5,6-dihydroimidazo[2,1-b]thiazol-3-yl)-2-furyl]-hydroxy-oxo-ammonium
State
State

At room temperature, Nithiazide is a solid. It is stable under normal conditions but should be stored in a cool, dry place to maintain its stability.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.00
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.00
General information
Molecular weight
203.21g/mol
Molar mass
203.2110g/mol
Density
1.3400g/cm3
Appearence

Nithiazide is typically found as a crystalline powder. It may appear as an off-white to light yellow solid, depending on its purity and the presence of any impurities.

Comment on solubility

Solubility Overview

The compound [5-(5,6-dihydroimidazo[2,1-b]thiazol-3-yl)-2-furyl]-hydroxy-oxo-ammonium presents an intriguing profile in terms of solubility. Understanding its solubility is crucial for its applications, particularly in chemical reactions and pharmaceutical formulations. Here are some key aspects to consider:

Factors Influencing Solubility

  • Polarity: The presence of hydrophilic functional groups may enhance solubility in polar solvents, while hydrophobic portions may lead to greater solubility in organic solvents.
  • Hydrogen Bonding: This compound features potential hydrogen bond donors and acceptors, impacting its interactions with solvents.
  • pH Level: The behavior of ammonium compounds can vary significantly with changes in pH, affecting solubility in aqueous environments.

General Solubility Trends

In many cases involving similar compounds, one might observe:

  • High Solubility: Often in polar solvents like water, especially if the compound has ionic characteristics.
  • Moderate Solubility: In organic solvents, particularly if the compound has a balanced structure of polar and non-polar regions.
  • Low Solubility: If the compound predominantly exhibits hydrophobic characteristics.

In summary, the solubility of [5-(5,6-dihydroimidazo[2,1-b]thiazol-3-yl)-2-furyl]-hydroxy-oxo-ammonium can vary based on its unique structural features. Therefore, thorough experimentation is vital to accurately assess its solubility profile in various solvents. Understanding these parameters is essential for optimizing its use in different chemical contexts.

Interesting facts

Interesting Facts about [5-(5,6-dihydroimidazo[2,1-b]thiazol-3-yl)-2-furyl]-hydroxy-oxo-ammonium

This intriguing compound holds a significant position in the realm of chemical research and medicinal chemistry. Here are some fascinating insights:

  • Biological Activity: The compound is often studied for its potential biological activities, which could lead to the development of novel pharmacological agents. Structures like this are of interest because they may exhibit unique mechanisms of action against various diseases.
  • Multifunctional Nature: Incorporating both a furyl ring and imidazo-thiazole moiety can yield multifunctional properties, making it suitable for various applications, including as a biomarker in disease studies or as a lead compound in drug design.
  • Research Significance: Researchers have highlighted the importance of compounds with the imidazo-thiazole scaffold for their *antimicrobial* and *antitumor* properties. This particular compound's hydroxyl and oxo groups further enhance its potential bioactivity.
  • Chemistry Connections: The synthesis of this compound typically involves various organic reactions, showcasing the blending of *heterocyclic chemistry* and *organometallic chemistry*. It's an excellent example for students learning about complex synthetic pathways in a laboratory setting.
  • Cyclic and Linear Structures: The interplay between cyclic and linear arrangements of atoms in such compounds teaches valuable lessons in conformational analysis and molecular geometry. Understanding how these arrangements affect reactivity is fundamental in organic chemistry.

In conclusion, [5-(5,6-dihydroimidazo[2,1-b]thiazol-3-yl)-2-furyl]-hydroxy-oxo-ammonium is not just a compound of theoretical interest but a representation of real-world applications and research potential in the chemical and medicinal fields. It embodies the essential spirit of scientific exploration, aiming not just for knowledge but also for the advancement of human health.