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Vitamin B12

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Identification
Molecular formula
C63H88CoN14O14P
CAS number
68-19-9
IUPAC name
[5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl] [1-methyl-2-[3-[2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3,5,8,8,13,15,18,19-octamethyl-1,2,7,12,17,23-hexahydrocorrin-3-yl]propanoylamino]ethyl] hydrogen phosphate
State
State

At room temperature, Vitamin B12 is a solid.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
1355.37g/mol
Molar mass
1 355.3650g/mol
Density
1.3500g/cm3
Appearence

Vitamin B12 appears as dark red crystals or crystalline powder.

Comment on solubility

Solubility of [5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl] [1-methyl-2-[3-[2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3,5,8,8,13,15,18,19-octamethyl-1,2,7,12,17,23-hexahydrocorrin-3-yl]propanoylamino]ethyl] hydrogen phosphate

The solubility of this complex compound, C63H88CoN14O14P, is quite notable due to its intricate structural features. Understanding its solubility characteristics is essential for many applications, particularly in biological and pharmaceutical contexts. Here are key points to consider:

  • Hydrophilicity vs. Hydrophobicity: The presence of polar functional groups, such as hydroxyl and amine groups, generally enhances solubility in aqueous environments.
  • Complexation: The coordination of cobalt (Co) in the structure may affect solubility and interactions with water. Metal-organic compounds often show interesting solubility profiles.
  • Concentration Dependence: At high concentrations, solubility can be influenced by intermolecular interactions, which may lead to precipitation.
  • pH Sensitivity: The solubility might change with pH, particularly in the presence of acidic or basic conditions that can protonate or deprotonate certain groups.

In conclusion, while detailed empirical data on this specific compound's solubility may require experimental investigation, one can anticipate that the balance of hydrophilic and hydrophobic parts within its structure will play a crucial role in determining its overall solubility characteristics. Understanding these factors can aid in optimizing conditions for its use in various applications.

Interesting facts

Interesting Facts About [5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl] [1-methyl-2-[3-[2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3,5,8,8,13,15,18,19-octamethyl-1,2,7,12,17,23-hexahydrocorrin-3-yl]propanoylamino]ethyl] hydrogen phosphate

This complex compound exemplifies the intricate world of bioinorganic chemistry, particularly in its application as a potential therapeutic agent. The compound features a unique cobalt-centered corrin structure, which is crucial in biological systems, often functioning similarly to heme in hemoglobin. This underlines the critical role of transition metals in biological processes.

Key Aspects of the Compound:

  • Structural Diversity: The compound consists of multiple functional groups, making it a promising candidate for drug design.
  • Biological Relevance: Its structural components suggest potential roles in enzyme mimicking and as a drug carrier.
  • Stability of the Corrin Framework: Corrins are known for their robustness, which is essential for maintaining biological activity in varying environments.

Moreover, compounds with such sophisticated architectures often lead to fascinating discoveries in medicinal chemistry, especially in treating diseases like cancer, where targeting specific pathways is vital. Researchers are constantly exploring how modifications to existing structures can enhance efficacy and reduce toxicity.

In summary, this compound is not only a remarkable illustration of the complexity achievable in organic synthesis but also serves as a reminder of the delicate interplay between chemistry and biology.

Synonyms
Citrofen-hydroxocobalamin acetate
PD063007