Skip to main content

NADP+

ADVERTISEMENT
Identification
Molecular formula
C21H29N7O17P3
CAS number
53-59-8
IUPAC name
[[5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate
State
State

At room temperature, NADP+ is in a solid state.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
743.40g/mol
Molar mass
743.4040g/mol
Density
0.2922g/cm3
Appearence

NADP+ typically appears as a white to off-white crystalline powder. It is a coenzyme found in all living cells, and is more commonly in its reduced form, NADPH. Its solutions are clear and colorless.

Comment on solubility

Solubility of the Compound

The compound [5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate, with the formula C21H29N7O17P3, presents an intricate picture with respect to its solubility due to its complex molecular structure.

Factors Influencing Solubility:

  • Polarity: The presence of multiple hydroxyl groups (-OH) and phosphate groups contributes to the compound's overall polarity, which is favorable for solubility in polar solvents like water.
  • Ionic Interactions: Given the presence of a carbamoylpyridin-1-ium moiety, ionic interactions may occur, enhancing solubility in ionic media.
  • Hydrogen Bonding: The potential for extensive hydrogen bonding due to hydroxyls likely increases solubility in water, as these interactions stabilize the compound in solution.

However, it is important to note that solubility can also be affected by external factors:

  • pH Levels: The solubility may vary at different pH levels, especially with the presence of ionizable groups in the compound.
  • Temperature: Increased temperature often enhances solubility; thus, heating may be beneficial for dissolving this compound effectively.

In summary, while this complex compound is expected to exhibit good solubility in polar solvents, its precise solubility characteristics can depend heavily on the conditions in which it is evaluated. Understanding these factors can lead to a more effective application in research and development.

Interesting facts

Interesting Facts about the Compound

This complex chemical compound signifies the fascinating intersection of organic chemistry and biochemistry. Comprising multiple functional groups, it exhibits unique characteristics that contribute to its potential applications.

Notable Attributes

  • Multi-Functional Molecule: The compound features various functional groups, including amines, hydroxyls, and phosphates, which can facilitate diverse reactivity profile.
  • Biological Relevance: Its intricate structure, which includes elements commonly found in nucleotides, suggests potential roles in biological processes such as energy transfer or signaling pathways.
  • Phosphorylation Potential: The presence of phosphate groups is vital for many biochemical reactions, particularly in the formation of nucleic acids and cellular signaling.
  • Tetrahydrofuran Structure: The inclusion of tetrahydrofuran rings offers interesting stereochemistry that could influence the compound’s physical and chemical interactions.

As a fellow scientist or chemistry student, you might find it intriguing to delve deeper into this compound’s synthesis.
The synthesis often involves a series of carefully controlled reaction steps and purification processes, illustrating the importance of reaction conditions in achieving the desired product. Scientists have been exploring compounds like this for their potential therapeutic applications, particularly in drug discovery.

Potential Applications

  • Pharmaceutical Development: Due to its molecular structure, the compound may serve as a scaffold for developing novel therapeutics.
  • Biochemical Research: Understanding the behavior of such compounds can illuminate cellular processes and metabolic pathways.
  • Biotechnology: It may also find uses in the bioconjugation technology, allowing binding with biomolecules for targeted delivery systems.

In summary, this compound represents a remarkable blend of synthetic complexity and biological significance, making it a valuable subject for research endeavors. As you explore its depths, consider the myriad possibilities that such intricate molecular architectures can offer!

Synonyms
MFCD00067537
NADP zwitterion
beta-Triphosphopyridine Nucleotide
SCHEMBL23273670
SCHEMBL24328678
SY055936
TPN
Nicotinamide-adenine dinucleotide, reduced, disodium salt (NADH)