Skip to main content

NAD+

ADVERTISEMENT
Identification
Molecular formula
C21H27N7O14P2
CAS number
53-84-9
IUPAC name
[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate
State
State
NAD+ generally exists in a solid state at room temperature. As a biochemical compound present in cells, it may also exist in solution within biological systems.
Melting point (Celsius)
140.00
Melting point (Kelvin)
413.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
663.43g/mol
Molar mass
663.4250g/mol
Density
1.3870g/cm3
Appearence

Nicotinamide adenine dinucleotide (NAD+) is a white to off-white solid that is hygroscopic, meaning it can absorb moisture from the environment. As a fine powder or crystalline solid, it may appear as a slightly yellowish substance if not pure.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

The solubility of the compound C21H27N7O14P2 is an important characteristic that influences its application in various fields, particularly in pharmaceuticals and biochemistry. The compound exhibits several factors that contribute to its solubility profile:

  • Hydrogen Bonding: Presence of functional groups such as hydroxyl (-OH) and amino (-NH2) can enhance solubility in polar solvents by forming hydrogen bonds.
  • Ionic Nature: The inclusion of positively charged groups, like carbamoylpyridin-1-ium, can lead to increased solubility in aqueous environments due to ion-dipole interactions.
  • Structural Complexity: The branched tetrahydrofuran rings can influence solubility, providing a degree of flexibility and steric hindrance that can affect how this compound interacts with solvents.

It is important to note that:

  1. Solubility in water: Likely enhanced due to polar functional groups.
  2. Solubility in organic solvents: Dependent on the solvent polarity; moderate to high solubility can be expected in polar aprotic solvents.

This compound's solubility can be summarized as being significantly influenced by its hybrid structure, with both hydrophilic and lipophilic characteristics. Understanding these properties is crucial for its effective usage and expansion of its practical applications.

Interesting facts

Interesting Facts about [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

This compound, with its complex structure and unique functional groups, presents fascinating aspects of both biological and synthetic chemistry. Here are some intriguing highlights:

  • Structure Complexity: The molecule features a combination of purine derivatives and tetrahydrofuran, creating a unique structural framework that can potentially influence biological activity.
  • Biological Relevance: Compounds similar to this one are often studied for their roles in nucleic acid biochemistry. The presence of aminopurine suggests potential interactions with DNA and RNA, making it a candidate for research in genetic studies.
  • Enzymatic Interactions: The unique functional groups, such as the methoxy and hydroxyphosphoryl, may allow this compound to mimic natural substrates in enzymatic reactions. This can lead to innovative approaches in drug design.
  • Chemical Versatility: The phosphonate moiety in the compound indicates potential applications in medicinal chemistry, especially in the development of antiviral and anticancer agents.
  • Potential Applications: This compound could be useful in areas such as:
    • Antiviral drug development
    • Biochemical research to study nucleic acids
    • Drug design targeting specific biological pathways

In summary, the intricate design and multiple functional groups of this compound open up a wide range of possibilities in the fields of biochemistry and drug synthesis. As a scientist or chemistry student, exploring its properties could lead to groundbreaking discoveries!

Synonyms
65085-09-8
BCP2132X
SCHEMBL19088452
SCHEMBL19997361
PD062454
1-(5-{[({[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxy]methyl}-3,4-dihydroxyoxolan-2-yl)-3-carbamoyl-1??-pyridin-1-ylium