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NADP+

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Identification
Molecular formula
C21H28N7O17P3
CAS number
53-59-8
IUPAC name
[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-[3-carbamoyl-4-(pyridine-4-carbonyl)pyridin-1-ium-1-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate
State
State

At room temperature, NADP+ is typically found in a solid crystalline form. It is stable under normal conditions but should be stored away from light and moisture to prevent degradation.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
578.15
Boiling point (Kelvin)
851.30
General information
Molecular weight
745.42g/mol
Molar mass
745.4210g/mol
Density
1.4540g/cm3
Appearence

NADP+ typically appears as a crystalline white powder. It is hygroscopic and sensitive to air and light, which can cause it to appear slightly off-white if it has been exposed to such conditions for extended periods.

Comment on solubility

Solubility of [[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-[3-carbamoyl-4-(pyridine-4-carbonyl)pyridin-1-ium-1-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate (C21H28N7O17P3)

The solubility of a compound like C21H28N7O17P3 is influenced by its structural characteristics, including the presence of functional groups and overall polarity. For this particular compound, several important factors contributing to its solubility are:

  • Polarity: The hydrophilic groups, such as hydroxyl (-OH) and phosphoryl (-PO4), typically enhance soluble interaction with water.
  • Ionic nature: The presence of positively charged or ionic groups can lead to improved solubility in polar solvents.
  • Size and steric hindrance: Larger molecular size or complex structures may hinder dissolution by reducing molecular mobility.
  • Hydrogen bonding: The capability of forming hydrogen bonds with solvent molecules significantly affects solubility.

As a result of these factors, this compound may exhibit a moderate to low solubility in water, with potential for increased solubility in polar organic solvents. Understanding the solubility characteristics is crucial, as it can influence the bioavailability and overall application of the compound in various fields such as pharmaceuticals and biochemistry. As the saying goes, "Like dissolves like," indicating that similar polarities will enhance solubility.

Interesting facts

Interesting Facts about the Compound

This compound, known for its complex structure, is a remarkable example of biochemical multitasking. It incorporates elements that are pivotal in several biological processes. Here are some fascinating aspects of this compound:

  • Biochemical Significance: Its structure consists of a tetrahydrofuran backbone which is crucial in mimicking nucleotides and nucleic acids, thereby playing a role in genetic coding and cellular function.
  • Phosphorylation Role: The presence of phosphate groups suggests its involvement in phosphorylation processes, which are vital for signal transduction pathways in cells.
  • Amino Group Functionality: The inclusion of an amino group enhances its role in serving as a building block for protein synthesis and may also impart unique reactivity properties.
  • Potential Therapeutic Applications: Given its complex structure, this compound has potential in medicinal chemistry, particularly in developing pharmaceuticals that target specific biological pathways.
  • Research Tool: Compounds like this are often used in research laboratories to study enzyme mechanisms and cellular processes due to their structural similarities to biologically relevant molecules.

To quote a famous chemist, "In chemistry, the simple is often more complex than what meets the eye." This compound serves as a perfect illustration of that principle. Its intricate makeup not only reflects its potential applications but also highlights the beauty of molecular design in nature.

Scientists and researchers continue to explore compounds like this to unlock new biological insights and therapeutic avenues. Its multifaceted nature exemplifies the interplay between structure and function in organic chemistry.