NADH | Solubility of Things

Identification

Molecular formula

C₂₁H₂₇N₇O₁₄P₂

CAS number

53-84-9

IUPAC name

[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-(5-carbamoyl-2-hydroxy-3,4-dihydro-2H-pyridin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

State

In its pure form, NADH is a solid at room temperature. It is usually handled as a solution in biochemical labs, where it serves as an essential coenzyme in redox reactions.

Melting point (Celsius)

140.00

Melting point (Kelvin)

413.15

Boiling point (Celsius)

0.00

Boiling point (Kelvin)

0.00

General information

Molecular weight

743.41g/mol

Molar mass

663.4250g/mol

Density

1.5728g/cm³

Appearence

NADH is typically a white, crystalline powder. It is more commonly encountered in solution form in biochemical laboratories, where it appears colorless. It fluoresces under UV light, aiding its use in certain biochemical assays.

Comment on solubility

Solubility of the Compound

The solubility of the compound 5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [5-(5-carbamoyl-2-hydroxy-3,4-dihydro-2H-pyridin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate (C₂₁H₂₇N₇O₁₄P₂) presents several noteworthy characteristics:

Highly polar structure: The presence of hydroxyl groups (-OH) and phosphate groups (–PO₄H) generally contributes to enhanced solubility in polar solvents such as water.

Hydrogen bonding: The ability of the compound to form hydrogen bonds with solvent molecules further supports its solubility in aqueous environments.

Influence of functional groups: The complex aromatic and heterocyclic rings may also affect the solubility, potentially making it less soluble in non-polar solvents.

In conclusion, the main factors influencing the solubility of this compound include its polarity, the ability to form hydrogen bonds, and the nature of its functional groups. Understanding these interactions is crucial for predicting how this compound behaves in different solvents, which can inform its practical applications in various fields.

Interesting facts

Interesting Facts about the Compound

The compound with the complex name involves a series of interesting functional groups and structural features that highlight its potential significance in various fields, particularly medicinal chemistry. Here are some noteworthy aspects:

Structural Complexity: The compound features multiple heterocyclic rings, incorporating both nitrogen and carbon atoms, which can contribute to various interactions with biological targets.

Biological Relevance: Given its structure, this compound may play a role in biological processes, potentially acting as a precursor or analog to important biological molecules.

Potential Therapeutic Applications: Compounds that contain purine and pyridine derivatives are of significant interest in the development of pharmaceuticals, especially in the realms of anti-cancer and anti-viral agents.

Phosphate Moiety: The presence of the phosphoryl group is particularly intriguing, as phosphate compounds are vital in energy transfer within biological systems, including ATP (adenosine triphosphate), which is essential for cellular functions.

Synthetic Pathways: The synthesis of such compounds often involves advanced organic chemistry techniques, making it a fascinating subject for research and development in synthetic methodologies.

Intermolecular Interactions: The varied functional groups can lead to interesting intermolecular interactions, including hydrogen bonding, which can affect the compound’s solubility and biological efficacy.

Research Opportunities: Due to its complex structure, this compound invites extensive research into its properties, synthesis, and applicability in various scientific domains.

In summary, the multifaceted nature of this compound presents numerous avenues for exploration, making it a compelling candidate for studies in biochemistry and pharmaceutical development.