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Deoxyadenosine triphosphate

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Identification
Molecular formula
C10H16N5O12P3
CAS number
1927-31-7
IUPAC name
[5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl] [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate
State
State

At room temperature, deoxyadenosine triphosphate is typically a solid.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
490.97g/mol
Molar mass
491.1780g/mol
Density
2.4300g/cm3
Appearence

Deoxyadenosine triphosphate typically appears as a white, crystalline powder. It's often found in its anhydrous form. Its crystalline nature is due to its well-defined molecular structure. The powder is highly hygroscopic, meaning it absorbs moisture readily from the environment, and can become sticky if exposed to humid conditions.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl] [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

The solubility of complex compounds such as [5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl] [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate (C10H16N5O12P3) can be influenced by several factors:

  • Polarity: Given that this compound contains numerous functional groups, it is likely to exhibit considerable polarity, which can enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The presence of hydroxyl groups may facilitate hydrogen bonding with solvent molecules, further promoting solubility.
  • Temperature: Solubility can be temperature-dependent, with increased temperatures often leading to greater solubility of many organic compounds.
  • pH Levels: The compound's solubility might also vary with pH, impacting the ionization of the functional groups.

In general, complex chemical structures tend to exhibit unique solubility behaviors that make them suitable for specific applications, particularly in pharmaceuticals and biochemistry. As noted, while this compound is expected to be soluble in water due to its polar characteristics, precise solubility data can vary, and *experimental validation is essential* to determine its behavior in various solvents.

Interesting facts

Interesting Facts About [5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl] [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

This compound is a fascinating example of a nucleotide analogue, which plays an important role in bioorganic chemistry and molecular biology. Here are some notable aspects of this complex molecule:

  • Biological Significance: It resembles nucleotides, the building blocks of DNA and RNA, hinting at potential applications in drug development, especially in antiviral and anticancer therapies.
  • Structure and Function: The fusion of the purine and pyrimidine components in its structure signifies a unique interplay between two fundamental genetic bases, which may enhance its biological activity.
  • Phosphorylation: Being a phosphonomethyl compound, it suggests an interesting mechanism for activating or inactivating biological pathways through phosphorylation, a critical post-translational modification.
  • Research Potential: Researchers are keenly studying this compound for its ability to inhibit certain enzymes, presenting new avenues in the treatment of diseases that involve these targets.
  • Complex Synthesis: Its synthesis offers an exciting challenge to chemists, often requiring multiple steps and sophisticated techniques, showcasing the intricacies of modern organic synthesis.

In conclusion, this compound exemplifies the intersection of chemistry and biology, offering a glimpse into how sophisticated chemical structures can influence life at the molecular level. As quoted by many chemists: "The magic lies in the complex structures that tell the story of life's chemical foundations."

Synonyms
SCHEMBL22765783
PD043135