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Coenzyme A

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Identification
Molecular formula
C21H36N7O16P3S
CAS number
85-61-0
IUPAC name
[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [3-hydroxy-4-[[3-[2-[2-[2-(1H-indol-3-yl)ethylamino]-2-oxo-ethyl]sulfanylethylamino]-3-oxo-propyl]amino]-2,2-dimethyl-4-oxo-butyl] hydrogen phosphate
State
State

Coenzyme A is typically found as a solid under standard conditions. It is stable in dry form and exhibits hygroscopic properties, meaning it absorbs moisture from the environment. This can affect its stability and storage.

Melting point (Celsius)
-1.00
Melting point (Kelvin)
-1.00
Boiling point (Celsius)
-1.00
Boiling point (Kelvin)
-1.00
General information
Molecular weight
767.54g/mol
Molar mass
767.5350g/mol
Density
1.6000g/cm3
Appearence

Coenzyme A is a white to off-white crystalline powder. It is typically odorless and has a slightly bitter taste. In solution, it can appear slightly yellowish due to its absorbance properties.

Comment on solubility

Solubility of [5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [3-hydroxy-4-[[3-[2-[2-[2-(1H-indol-3-yl)ethylamino]-2-oxo-ethyl]sulfanylethylamino]-3-oxo-propyl]amino]-2,2-dimethyl-4-oxo-butyl] hydrogen phosphate

This intriguing compound, with the formula C21H36N7O16P3S, presents unique challenges and characteristics regarding its solubility. Understanding its solubility is essential for its potential applications and interactions in various environments. Here are some key points:

  • Polarity: The presence of multiple functional groups, including phosphate and amino groups, suggests that the compound may be polar and therefore more soluble in polar solvents, such as water.
  • Hydrophilicity: The functional groups can impart hydrophilic characteristics, enhancing its solubility in aqueous solutions.
  • Solvent Dependence: Solubility may vary significantly between solvents. For instance, while it may readily dissolve in aqueous solutions, its behavior in non-polar solvents could be markedly different.
  • Concentration Impacts: At higher concentrations, solubility limits could be reached, leading to precipitation or reduced bioavailability, which is critical in pharmaceutical contexts.

In summary, while the solubility of this compound cannot be precisely defined without experimental data, it is likely to be moderate to high in polar solvents, primarily due to its complex structure composed of multiple hydrophilic moieties. Understanding these solubility characteristics is essential for elucidating its potential applications and optimizing its use in various fields.

Interesting facts

Interesting Facts About the Compound

This compound presents a fascinating blend of biological relevance and chemical complexity, primarily due to its intricate structure that includes various functional groups. Here are some intriguing points to consider:

  • Biological Significance: The compound is structurally related to nucleotide analogs, which play crucial roles in cellular processes such as energy transfer and signal transduction.
  • Phosphorylation Dynamics: The presence of multiple phosphate groups suggests that this compound could be vital in biological phosphorylation processes, which are critical for regulating enzymatic activity and cell signaling pathways.
  • Potential Therapeutic Applications: Compounds like this one have been investigated for their potential use in drug development, especially in targeting certain types of cancer or viral infections. The interplay of its components could enhance therapeutic efficacy.
  • Complex Synthesis: The synthesis of such compounds requires advanced chemical techniques, illustrating the remarkable capabilities of modern chemistry in creating bioactive molecules. This complexity can challenge both researchers and synthetic chemists alike.
  • Multifunctionality: The functional groups in the compound indicate that it may exhibit multiple biological activities, making it a candidate for further studies in medicinal chemistry.

As noted in the field, "The beauty of organic chemistry lies in its complexity and diversity." Thus, the exploration of compounds like this one continues to push the boundaries of what is achievable in both research and application. Understanding and harnessing the properties of such intricate molecules can lead to significant advancements in pharmaceuticals and biotechnology.

Synonyms
CID2822; (Acyl-CoA); [M+H]+;