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Hinokiflavone

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Identification
Molecular formula
C30H18O10
CAS number
10372-57-3
IUPAC name
5-[[7,8-dihydroxy-2-(2-thienyl)-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxy-phenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one
State
State

Hinokiflavone is solid at room temperature. It is often extracted from various plant sources and exists as a dry powder with a stable configuration under normal conditions.

Melting point (Celsius)
312.00
Melting point (Kelvin)
585.15
Boiling point (Celsius)
354.00
Boiling point (Kelvin)
627.15
General information
Molecular weight
538.42g/mol
Molar mass
538.4150g/mol
Density
1.5800g/cm3
Appearence

Hinokiflavone typically appears as a yellowish crystalline powder. It has a characteristic structure due to its biflavonoid nature and exhibits moderate solubility in organic solvents.

Comment on solubility

Solubility of 5-[[7,8-dihydroxy-2-(2-thienyl)-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxy-phenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one (C30H18O10)

The solubility of this complex compound can be described as moderate, influenced by several factors that include its structural characteristics and the presence of functional groups. Here are some key points regarding its solubility:

  • Polarity: Due to various hydroxyl (-OH) groups present, the compound exhibits some polar characteristics which can enhance solubility in polar solvents such as water.
  • Hydrophobic Regions: The compound also contains hydrophobic portions attributed to the dioxol and thienyl rings, which may lead to limited solubility in highly polar solvents.
  • Solvent Choice: The solubility tends to improve in organic solvents such as ethanol and methanol, where the compound can better interact.
  • Temperature Dependency: The solubility may increase with temperature, a common phenomenon for many organic compounds.

In summary, while this compound displays certain attributes that may facilitate solubility, its overall behavior is highly specific to the environment in which it is assessed. It is essential to consider both polar and non-polar interactions to fully understand its solubility profile.

Interesting facts

Introduction to an Intriguing Compound

The compound 5-[[7,8-dihydroxy-2-(2-thienyl)-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxy-phenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one is a fascinating entity in the world of chemistry, distinguished by its complex structure and potential applications in various fields. Here are some interesting aspects of this compound:

1. Complexity of Structure

  • The intricate connectivity of the molecule showcases a rich tapestry of atoms, including multiple rings and functional groups.
  • Its structure features elements like dioxins and pyrano derivatives, which are known for their varied biological activities.

2. Potential Biological Activity

  • Compounds featuring similar frameworks often exhibit potential pharmacological properties, including anti-inflammatory and antioxidant effects.
  • Research on related compounds suggests they may play a role in the development of new therapeutic agents.

3. Applications in Natural Products

  • This compound could serve as a model for natural products that occur in medicinal plants or can be synthesized from them.
  • It may be investigated for use in nutraceuticals or herbal remedies, reflecting traditional uses in medicine.

4. Synthesis Challenges

  • The synthesis of such a complex molecule can pose significant challenges in terms of reaction conditions, yield, and purity.
  • Advancements in organic synthesis techniques can help chemists create this compound more efficiently.

In summary, the multifaceted nature of this compound makes it a subject of interest in organic chemistry and medicinal research. As stated by many chemists, “Understanding the intricacies of complex molecules not only expands our scientific knowledge but also paves the way for innovative solutions in medicine and industry.

Synonyms
MLS000766234
SMR000528847
Tenoposide
Vehem-sandoz
Veham-Sandoz
VM 26
NSC 122819
125851-00-5
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-2-thenylidene-beta-D-glucopyranoside)
cid_5396
Neuro_000056
4'-Demethylepipodophyllotoxin-.beta.-D-thenylideneglucoside
4'-Demethyl-epipodophyllotoxin-.beta.-D-thenylidene-glucoside
Epipodophyllotoxin-.beta.-D-thenylidene-glucoside, 4'-demethyl-
CHEMBL1571037
SCHEMBL13809319
BDBM87330
DTXSID60860440
4'-Demethyl 1-O-(4,6-O,O-(2-thenylidene)-.beta.-D-glucopyranosyl)epipodophyllotoxin
4'-Demethylepipodophyllotoxin 9-(4,6-O-2-thenylidene-.beta.-D-glucopyranoside)
[5R-[5.alpha.,5a.beta.,8a.alpha.,9.beta.(R*)]]-5,8,8a,9-Tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-(2-thienylmethylene)-.beta.-d-glucopyranosyl]oxy]furo[3',4':6,7]-naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-((4,6-O-(2-thienylmethylene)-.beta.-D-glucopyranosyl)oxy)-, (5R-(5.alpha.,5a.beta.,8a.alpha.,9.beta.(R*)))-
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-(2-thienylmethylene)-.beta.-D-glucopyranosyl)
AKOS026750133
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-2-thenylidene-.beta.-D-glucopyranoside)
NS00010051
SR-01000775528
SR-01000775528-2
9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(thiophen-2-yl)methylidene]hexopyranoside