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Congo Red

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Identification
Molecular formula
C32H22N6Na2O6S2
CAS number
573-58-0
IUPAC name
5-acetamido-2-[2-(4-isothiocyanato-2-sulfo-phenyl)vinyl]benzenesulfonic acid
State
State

Congo Red is typically found in a solid state at room temperature.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
696.67g/mol
Molar mass
696.6650g/mol
Density
0.9431g/cm3
Appearence

Congo Red appears as a reddish-brown powder that has a striking color change depending on the pH of the solution it is in. It is a pH indicator dye, and it exhibits a blue color at acidic pH and a red color at neutral and basic pH.

Comment on solubility

Solubility of 5-acetamido-2-[2-(4-isothiocyanato-2-sulfo-phenyl)vinyl]benzenesulfonic acid

The solubility of 5-acetamido-2-[2-(4-isothiocyanato-2-sulfo-phenyl)vinyl]benzenesulfonic acid in various solvents is quite intriguing due to its complex structure.

Here are some key points regarding its solubility:

  • Water Solubility: This compound is likely to be soluble in water, primarily because of the -SO₃H (sulfonic acid) and -NH₃ (amide) functional groups, both of which are known to enhance solubility in polar solvents.
  • Polar Organic Solvents: It may also exhibit solubility in some polar organic solvents, such as methanol and ethanol, as the presence of polar functional groups aids dissolution.
  • Non-Polar Solvents: Conversely, the solubility in non-polar solvents is expected to be low. This is attributed to the significant number of polar groups that do not favor interactions with non-polar environments.
  • pH Dependency: The solubility can also be affected by the pH of the solution. At varying pH levels, the ionization state of the sulfonic and amido groups can change, influencing the overall solubility.

To sum up, the solubility of this compound is predominantly influenced by its ionic and polar characteristics, making it well-suited for aqueous environments. Understanding these solubility trends is essential for its applications in chemical and biochemical contexts.

Interesting facts

Interesting Facts about 5-acetamido-2-[2-(4-isothiocyanato-2-sulfo-phenyl)vinyl]benzenesulfonic acid

This compound, often recognized for its complex structure, brings a fascinating array of properties and applications to the field of chemistry. Here are some intriguing facts:

  • Versatile Reactivity: The inclusion of isothiocyanate and sulfonic acid functional groups grants this compound significant reactivity, making it a valuable building block in organic synthesis.
  • Application as a Labeling Agent: Due to its unique structure, this compound is often used as a fluorescent labeling agent in biochemical assays, allowing for novel visualization techniques in cell biology and medical research.
  • Potential Use in Diagnostics: Scientists are exploring the application of this compound in diagnostic imaging and as a probe in biosensors, enhancing the detection of specific biomolecules.
  • Insight into Chemical Behavior: The sulfonic acid group in this compound significantly affects its chemical behavior, particularly in aqueous environments, affecting its polar nature and interaction with other molecules.
  • Rich Research Potential: The incorporation of multiple functional groups positions this compound at the forefront of research, particularly in the areas of material science and drug discovery.

As we continue to explore the potential of this remarkable compound, it reminds us of the intricacies of chemical structures and their profound impacts on science and industry.

Synonyms
DTXSID001191341
EZV5SX627H
NSC-328387
NSC-649691
27816-59-7
4-Acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid
SITS Disodium Salt
Disodium Salt, SITS
4 Acetamido 4' isothiocyanatostilbene 2,2' disulfonic Acid
Benzenesulfonic acid, 5-(acetylamino)-2-(2-(4-isothiocyanato-2-sulfophenyl)ethenyl)-
RefChem:912281
Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-
DTXCID201275915
SITS
NSC649691
SCHEMBL25796
SCHEMBL29351606
Benzenesulfonic acid,5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-
DS-010318
4-Acetamido-4'-isothiocyano-2,2'-disulfonic acid stilbene
2,2'-Stilbenedisulfonic acid, 4-acetamido-4'-isothiocyanato-
4-Acetamido-4a(2)-isothiocyanatostilbene-2,2a(2)-disulfonic acid
2,2'-Stilbenedisulfonic acid, 4-acetamido-4'-isothiocyanato-, (E)-
5-(Acetylamino)-2-[(1E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid
5-(Acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid
5-acetamido-2-[2-(4-isothiocyanato-2-sulfo-phenyl)vinyl]benzenesulfonic acid
Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, (E)-