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Kasugamycin

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Identification
Molecular formula
C14H25N3O9
CAS number
6980-18-3
IUPAC name
5-acetamido-2-[2-[5-acetamido-6-[5-acetamido-6-[(3-acetamido-4-amino-4-oxo-butanoyl)amino]-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid
State
State

The compound is solid at room temperature.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
511.48g/mol
Molar mass
511.4820g/mol
Density
1.5500g/cm3
Appearence

The compound is typically a white to off-white powder.

Comment on solubility

Solubility of 5-acetamido-2-[2-[5-acetamido-6-[5-acetamido-6-[(3-acetamido-4-amino-4-oxo-butanoyl)amino]-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid

Understanding the solubility of this complex compound, with the formula C14H25N3O9, is essential for its potential applications in various fields such as pharmaceuticals and biochemical research.

Here are some key points on its solubility:

  • Hydrophilicity: The presence of multiple hydroxyl groups (–OH) and acetamido groups (–C(O)NH2) in the structure makes this compound highly hydrophilic.
  • Solvent Compatibility: It is likely to be soluble in polar solvents such as water and alcohols, due to its capability to form hydrogen bonds.
  • Influence of pH: The carboxylic acid functional group may enhance solubility in acidic or neutral pH environments, while rendering it less soluble under strongly basic conditions.
  • Concentration Effects: The solubility may also vary with concentration; increased concentrations might lead to saturation points where precipitation occurs.

In summary, due to its multifaceted structure and functional groups, the solubility of 5-acetamido-2-[2-[5-acetamido-6-[5-acetamido-6-[(3-acetamido-4-amino-4-oxo-butanoyl)amino]-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid can generally be anticipated to be favorable in aqueous environments. However, precise solubility data should be obtained experimentally for practical applications.

Interesting facts

Interesting Facts about 5-acetamido-2-[2-[5-acetamido-6-[5-acetamido-6-[(3-acetamido-4-amino-4-oxo-butanoyl)amino]-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid

This compound, a complex derivative of tetrahydropyran, showcases some fascinating chemistry and biological significance. Here are some key points to consider:

  • Structure: The intricate structure is characterized by multiple acetamido and hydroxy groups, which play critical roles in its chemical behavior and potential reactivity.
  • Bioactivity: Compounds like this one may exhibit biological activity, particularly in medicinal chemistry, serving as potential drug candidates or lead compounds for further exploration.
  • Synthetic Routes: The synthesis of such a complicated structure involves advanced organic synthesis techniques, potentially including multi-step synthesis and careful manipulation of stereochemistry.
  • Pharmacological Potential: Due to the presence of functional groups, this compound could interact strategically with biological systems, possibly influencing metabolic pathways or receptor activities.
  • Research Applications: Compounds with similar architectures are often studied for their role in influencing enzyme activity, which could have implications in drug design and development.

In the words of a prominent chemist, "Understanding complexity in small molecules opens doors to breakthroughs in medical science." Therefore, the exploration of this compound may not only unravel its properties but also contribute to the discovery of new therapeutic avenues.


As you delve deeper into this compound, remember that every intricate bond and functional group represents a potential opportunity for innovation in the fields of chemistry and pharmacology!