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N-Acetylglucosamine phosphate

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Identification
Molecular formula
C8H16NO8P
CAS number
7512-17-6
IUPAC name
(5-acetamido-3,4,6-trihydroxy-tetrahydropyran-2-yl)methyl dihydrogen phosphate
State
State

At room temperature, N-Acetylglucosamine phosphate exists in a solid state. It is normally encountered as a crystalline powder and may be available in both anhydrous and hydrated forms. The crystalline solid is stable under typical storage conditions but should be stored in a cool, dry place to prevent moisture absorption.

Melting point (Celsius)
248.00
Melting point (Kelvin)
521.20
Boiling point (Celsius)
216.60
Boiling point (Kelvin)
489.80
General information
Molecular weight
299.21g/mol
Molar mass
299.2130g/mol
Density
1.6800g/cm3
Appearence

N-Acetylglucosamine phosphate typically appears as a white, crystalline powder. The compound is hygroscopic, meaning it can absorb moisture from the air, and is soluble in water, forming a colorless solution. The appearance details can vary slightly depending on the purity and form (e.g., anhydrous or hydrated) of the compound available.

Comment on solubility

Solubility of (5-acetamido-3,4,6-trihydroxy-tetrahydropyran-2-yl)methyl dihydrogen phosphate

The solubility of the compound (5-acetamido-3,4,6-trihydroxy-tetrahydropyran-2-yl)methyl dihydrogen phosphate, with the chemical formula C8H16NO8P, can be understood through several key aspects:

  • Polarity: This molecule contains multiple hydroxyl groups, which generally increases polarity, suggesting a higher tendency for solubility in polar solvents like water.
  • Ionization: The presence of a dihydrogen phosphate group allows for potential ionization, enhancing solubility further in aqueous solutions.
  • Hydrogen Bonding: The compound's structure allows for considerable hydrogen bonding with water molecules, promoting solvation.
  • Solvent Interaction: Solubility can vary significantly in different solvents; while the compound is expected to be soluble in water, it may have limited solubility in nonpolar organic solvents.

Overall, it is reasonable to conclude that (5-acetamido-3,4,6-trihydroxy-tetrahydropyran-2-yl)methyl dihydrogen phosphate is likely to be soluble in water due to its structural characteristics and the interactions it can engage in within aqueous environments.

Interesting facts

Interesting Facts about (5-acetamido-3,4,6-trihydroxy-tetrahydropyran-2-yl)methyl dihydrogen phosphate

This compound is a fascinating example of a carbohydrate-derived phosphoric acid derivative, characterized by a complex cyclic structure that contributes to its unique chemical behavior. Here are some intriguing aspects of this molecule:

  • Biological Relevance: This compound's structure suggests it may play a role in biological systems, particularly in processes involving phosphates, such as energy transfer and signal transduction.
  • Functional Groups: Notably, the inclusion of both acetamido and hydroxyl functional groups within its structure allows the molecule to exhibit both hydrophilic and hydrophobic properties. This dual nature can influence solubility in different environments.
  • Potential Applications: Due to its structural characteristics, it may find application in drug design and delivery systems, enhancing the bioavailability of certain therapeutic agents.
  • Structural Complexity: The multi-hydroxyl functional groups open up possibilities for hydrogen bonding, which can enhance its interaction with biomolecules. Such interactions can significantly affect its reactivity and stability.
  • Research Significance: As researchers understand the biochemical pathways that involve phosphates, compounds like this are likely to be of considerable interest. They enable scientists to explore how modifications to sugar structures can impact their biological roles.

In summary, the study of (5-acetamido-3,4,6-trihydroxy-tetrahydropyran-2-yl)methyl dihydrogen phosphate enriches our understanding of biochemical processes and offers potential avenues for future research and applications. Its intricate structure and significant functional groups make it a compound worthy of attention in both academic and industrial chemistry.

Synonyms
GlcNAc-6-P
(5-acetamido-3,4,6-trihydroxyoxan-2-yl)methyl dihydrogen phosphate
N-acetyl-D-glucosamine-6-phosphate
N-acetyl-glucosamine-6-phosphate
N-acetyl-D-galactosamine-6-phosphate
bmse000205
BRGMHAYQAZFZDJ-UHFFFAOYSA-N
AKOS015913292
102029-88-9