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Primidone

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Identification
Molecular formula
C12H14N2O2
CAS number
125-33-7
IUPAC name
5-allyl-1,3-dicyclohexyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, primidone is in solid state.

Melting point (Celsius)
279.00
Melting point (Kelvin)
552.00
Boiling point (Celsius)
440.00
Boiling point (Kelvin)
713.00
General information
Molecular weight
218.29g/mol
Molar mass
218.2850g/mol
Density
1.1950g/cm3
Appearence

Primidone appears as white, crystalline powder or colorless crystals. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 5-allyl-1,3-dicyclohexyl-hexahydropyrimidine-2,4,6-trione

The solubility of 5-allyl-1,3-dicyclohexyl-hexahydropyrimidine-2,4,6-trione is a critical aspect that influences its applications in various fields, particularly in pharmaceuticals and organic synthesis. Understanding the solubility characteristics can provide valuable insights into its behavior in different solvents. Here are some key points regarding its solubility:

  • Polar Solvents: Generally, compounds with polar functional groups tend to exhibit better solubility in polar solvents like water and methanol. However, the structure of this compound suggests limited solubility in highly polar solvents due to hydrophobic cyclohexyl rings.
  • Non-Polar Solvents: Conversely, compounds like 5-allyl-1,3-dicyclohexyl-hexahydropyrimidine-2,4,6-trione may find greater solubility in non-polar solvents such as hexane or diethyl ether, thanks to its hydrophobic characteristics.
  • Temperature Influence: Temperature can significantly affect solubility. Typically, increasing the temperature may enhance solubility for many organic compounds, including this trione.
  • Concentration Effects: As the concentration of the compound increases in solution, one may observe saturation effects, limiting further dissolution.

In summary, while 5-allyl-1,3-dicyclohexyl-hexahydropyrimidine-2,4,6-trione may face challenges in polar solvents, it presents fascinating solubility behavior in non-polar environments, which can influence its utility in chemical processes. It is essential for researchers to conduct solubility tests to ascertain the best solvent conditions for their specific applications.

Interesting facts

Interesting Facts about 5-Allyl-1,3-dicyclohexyl-hexahydropyrimidine-2,4,6-trione

The compound 5-Allyl-1,3-dicyclohexyl-hexahydropyrimidine-2,4,6-trione is a fascinating molecule that showcases the beauty of organic chemistry in its structure and potential applications. Here are some captivating aspects of this chemical:

  • Unique Structure: The presence of the hexahydropyrimidine ring system in this compound contributes to its interesting structural features, which can exhibit various tautomeric forms.
  • Potential Biological Activity: Compounds that incorporate pyrimidine moieties are often found in pharmacologically active substances, including some anticancer and antimicrobial agents.
  • Hydrophilic and Hydrophobic Interactions: The dicyclohexyl groups provide a significant hydrophobic environment, making this compound potentially interesting for drug design and delivery systems.
  • Allyl Group Significance: The allyl group in this molecule is known for its reactivity, making the compound a subject of study in synthetic organic chemistry for developing derivatives or analogs.

This compound serves as a reminder that organic compounds can possess a wealth of complexity and potential within their seemingly simple nomenclature. As a chemistry student or scientist, exploring such compounds not only enhances our understanding of organic structures but also fosters innovation in fields such as medicinal chemistry and materials science.

As we investigate compounds like 5-allyl-1,3-dicyclohexyl-hexahydropyrimidine-2,4,6-trione, we often find ourselves pondering the quote: "The more we learn, the more we realize how much we do not know." This sentiment captures the essence of scientific discovery and the ever-expanding frontier of chemical research.

Synonyms
743-43-1
5-Allyl-1,3-dicyclohexylbarbituric acid
BRN 0763691
BARBITURIC ACID, 5-ALLYL-1,3-DICYCLOHEXYL-
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-allyl-1,3-dicyclohexyl-
5-Allyl-1,3-dicyclohexyl-2,4,6(1H,3H,5H)-pyrimidinetrione
DTXSID60225313
DTXCID60147804
5-24-09-00215 (beilstein handbook reference)