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Dantrolene

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Identification
Molecular formula
C14H23N3O3
CAS number
7261-97-4
IUPAC name
5-allyl-5-[(1R)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, dantrolene is found in a solid state, specifically as a powder. Its solid form requires careful handling due to its potential to decompose or react under specific conditions.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.15
Boiling point (Celsius)
453.00
Boiling point (Kelvin)
726.15
General information
Molecular weight
314.36g/mol
Molar mass
314.3350g/mol
Density
1.2296g/cm3
Appearence

Dantrolene typically appears as a yellow, odorless crystalline powder. It is not very soluble in water but is more soluble in organic solvents, such as methanol and ethanol. It is known for its vibrant yellow crystalline structure.

Comment on solubility

Solubility of 5-allyl-5-[(1R)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione

The solubility of 5-allyl-5-[(1R)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione can vary depending on several factors, including temperature, solvent type, and the presence of other substances. Understanding its solubility characteristics can provide valuable insights into its potential applications and behavior in different environments.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups in the compound can influence its solubility in polar solvents like water.
  • Temperature: Generally, higher temperatures can increase solubility, making the compound more soluble in certain solvents.
  • Solvent Type: Solvents that can form hydrogen bonds are likely to dissolve this compound more effectively.
  • Concentration: The solubility may also be affected by the concentration of the compound in the solution.

While specific solubility data might not be readily available for 5-allyl-5-[(1R)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione, some general observations can be made:

  • It may display limited solubility in water due to its complex structure and potential hydrophobic portions.
  • The compound may exhibit better solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).

In conclusion, the solubility of this compound is a nuanced topic, driven by multiple factors. As such, experimental determination in various environmental conditions is essential for a comprehensive understanding of its solubility profile.

Interesting facts

Interesting Facts about 5-allyl-5-[(1R)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione

5-allyl-5-[(1R)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione is a fascinating compound that belongs to the class of pyrimidine derivatives, which are known for their significant role in biochemistry and medicinal chemistry.

Key Characteristics

  • Structural Diversity: This compound features a complex structure that includes both a pyrimidine ring and an allyl group, which can impact its reactivity and interaction with biological systems.
  • Biological Significance: Pyrimidine derivatives are often found in natural products and biologically active compounds. They play essential roles in cellular processes, such as DNA and RNA synthesis.
  • Potential Applications: Due to its structural features, this compound could be investigated for potential uses in pharmaceuticals. Studying such compounds can lead to the discovery of new drugs and therapies.

Interesting Insights

Researchers continuously explore the diverse functionalities of pyrimidine derivatives, including:

  • Antimicrobial Activity: Some derivatives have shown promising results in inhibiting bacterial and fungal growth.
  • Antiviral Properties: Certain pyrimidine compounds are studied for their ability to combat viral infections.
  • Trusted Platforms for Research: The versatility of this class of compounds makes them frequent subjects of research, often leading to breakthroughs in medical science.

As scientists delve deeper into the properties and potential applications of compounds like 5-allyl-5-[(1R)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione, they contribute to the vast and exciting field of organic chemistry and pharmacology. The intricate relationship between structure and function in these compounds makes them a promising area for future studies.

Synonyms
(+)-Secobarbital
(R)-(+)-Seconal
Secobarbital, (+)-
22328-94-5
S-(-)-Secobarbital
DTXSID7048873
BARBITURIC ACID, 5-ALLYL-5-(1-METHYLBUTYL)-, (R)-(+)-
HX75939EI7
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylbutyl)-5-(2-propenyl)-, (R)-
R(+)-Secobarbital
UNII-HX75939EI7
(R)-secobarbital
NCGC00247331-02
R(+)-5-Allyl-5-(1-methylbutyl)-barbituric acid
5-[(2R)-pentan-2-yl]-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
RefChem:1072294
SCHEMBL41181
SECOBARBITAL, (R)-
(R)-(+)-SECOBARBITAL
CHEMBL3561391
DTXCID0028799
SCHEMBL18740524
Tox21_112867
CAS-20224-45-7
Q27280144
2,4,6(1H,3H,5H)-PYRIMIDINETRIONE, 5-((1R)-1-METHYLBUTYL)-5-(2-PROPEN-1-YL)-
2,4,6(1H,3H,5H)-PYRIMIDINETRIONE, 5-((1R)-1-METHYLBUTYL)-5-(2-PROPENYL)-
5-((1R)-1-Methylbutyl)-5-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione