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Amobarbital

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Identification
Molecular formula
C11H18N2O3
CAS number
57-43-2
IUPAC name
5-allyl-5-[(1S)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione
State
State
Amobarbital is generally found in a solid state, and it is typically administered as a powder or in tablet form for medicinal purposes.
Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
226.29g/mol
Molar mass
226.2890g/mol
Density
1.1000g/cm3
Appearence

Amobarbital appears as a white, crystalline powder. It can also occur in tablet form, and when in crystal form, it may have a very faint odor. Barbiturates like amobarbital are known for their crystalline texture and typically solid state at room temperature.

Comment on solubility

Solubility of 5-allyl-5-[(1S)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione

5-allyl-5-[(1S)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione exhibits interesting solubility characteristics due to its complex molecular structure. Understanding the solubility of this compound is crucial for its applications in various fields, including pharmaceuticals and organic synthesis.

Key Points about Solubility:

  • Solvent Interaction: The solubility of this compound can significantly vary depending on the solvent used. Polar solvents like water may dissolve the compound to a limited extent, while organic solvents such as ethanol or methanol might enhance solubility.
  • Temperature Dependence: Solubility often increases with temperature. Thus, heating the solution may improve the dissolution of this compound.
  • Hydrogen Bonding: The presence of polar functional groups within the structure could facilitate hydrogen bonding, influencing the compound's solubility in polar solvents.
  • Structural Factors: The bulky alkyl side chains may hinder solubility in certain solvents, potentially leading to decreased interaction with solvent molecules.

In conclusion, the solubility of 5-allyl-5-[(1S)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione is a multifaceted property influenced by various factors. Getting a clearer insight requires exploring specific solvents, temperature conditions, and thorough experimental evaluations to enhance utility in practical applications.

Interesting facts

5-Allyl-5-[(1S)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione

This unique compound presents a fascinating intersection of organic chemistry and biochemistry, showcasing the complexity of molecular structure and function. With a focus on its potent activity and potential applications, we can uncover remarkable aspects of this compound:

  • Structural Complexity: The compound features a hexahydropyrimidine core, which is not only intriguing due to its multi-cyclic nature but also because it can demonstrate varied chemical reactivity.
  • Biological Relevance: Compounds similar to this one are often studied for their effects on biological systems, potentially influencing metabolic pathways or acting as intermediates in drug synthesis.
  • Allylic Substituents: The presence of an allyl group makes this compound a topic of interest for those studying the reactivity of compounds under different conditions, such as in allylic rearrangements.
  • Chirality: The (1S)-1-methylbutyl substituent introduces chirality, which is vital in pharmacology since the orientation of molecules can significantly impact their activity and interaction with biological targets.
  • Potential Applications: With its unique structure and properties, this compound may be explored for uses in pharmaceuticals, agrochemicals, or even as a model for educational demonstrations in organic chemistry.

In summary, 5-allyl-5-[(1S)-1-methylbutyl]hexahydropyrimidine-2,4,6-trione serves as an excellent example of how intricate organic molecules can pave the way for advancements in various scientific fields. Its exploration can inspire the next generation of chemists to delve deeper into the understanding of chemical reactivity and functional applications.

Synonyms
S(-)-Secobarbital
Secobarbital, (-)-
20224-45-7
R-(+)-Secobarbital
BARBITURIC ACID, 5-ALLYL-5-(1-METHYLBUTYL)-, (S)-(-)-
FG3SCI1960
DTXSID2048874
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylbutyl)-5-(2-propenyl)-, (S)-
UNII-FG3SCI1960
Quinal barbitone
(S)-secobarbital
NCGC00247331-02
NCGC00247712-01
S(-)-5-Allyl-5-(1-methylbutyl)-barbituric acid
(S)-(-)-Secobarbital
(-)-SECOBARBITAL
5-[(2S)-pentan-2-yl]-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
SCHEMBL80735
SECOBARBITAL, (S)-
MLS002320681
(S)-(-)-SECONAL
CHEMBL2144731
DTXCID2028800
HMS2272L06
Tox21_112868
NCGC00247331-01
SMR001338827
CAS-22328-94-5
NS00099227
(S)-5-ALLYL-5-(2'-PENTYL)BARBITURIC ACID
Q27277973
5-(1-Methylbutyl)-5-propenylbarbituric acid (quinal barbitone)
2,4,6(1H,3H,5H)-PYRIMIDINETRIONE, 5-((1S)-1-METHYLBUTYL)-5-(2-PROPEN-1-YL)-
2,4,6(1H,3H,5H)-PYRIMIDINETRIONE, 5-((1S)-1-METHYLBUTYL)-5-(2-PROPENYL)-