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Allobarbital

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Identification
Molecular formula
C10H12N4O3
CAS number
52-43-7
IUPAC name
5-allyl-5-(2-hydrazinylidenepropyl)hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, allobarbital exists as a solid. Its crystalline form adds to its solid state characteristics, making it stable under standard conditions. It is typically handled and stored as a powder.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
358.10
Boiling point (Kelvin)
631.25
General information
Molecular weight
224.23g/mol
Molar mass
224.2660g/mol
Density
1.1128g/cm3
Appearence

Allobarbital is a white, crystalline powder. It is odorless and has a slightly bitter taste. Its crystalline structure contributes to its powdery texture, making it easy to handle in laboratory and pharmaceutical settings.

Comment on solubility

Solubility of 5-allyl-5-(2-hydrazinylidenepropyl)hexahydropyrimidine-2,4,6-trione

The solubility of 5-allyl-5-(2-hydrazinylidenepropyl)hexahydropyrimidine-2,4,6-trione is a multifaceted topic that can be influenced by several factors. Here's what we know:

  • Polar vs Non-Polar Solvents: This compound's solubility can vary greatly in polar versus non-polar solvents. Because it contains multiple functional groups, it may exhibit higher solubility in polar solvents such as water, but limited solubility in non-polar solvents like hexane.
  • Temperature Effect: Like many organic compounds, increased temperature typically enhances solubility. The kinetic energy allows for better interaction between solute and solvent molecules.
  • pH Influence: The existence of hydrazine groups might show variable solubility in acidic or basic conditions, thus adjusting the pH of the solvent can impact the solubility significantly.
  • Complex Formation: This compound has the potential to form complexes with metal ions or other molecules in solution, which can further affect solubility.

As a general rule, it is crucial to conduct specific solubility tests to determine the precise behavior of this compound in various solvents. “Solubility is often considered the gateway to understanding the compound's reactivity and application potential.” Therefore, characterizing its solubility can provide valuable insights into its practical uses in various fields such as medicinal chemistry and industrial applications.

Interesting facts

Interesting Facts about 5-allyl-5-(2-hydrazinylidenepropyl)hexahydropyrimidine-2,4,6-trione

This intriguing compound belongs to the family of hexahydropyrimidines, which are known for their versatile chemistry and numerous applications in medicinal chemistry. Here are some fascinating insights:

  • Versatile Structure: The unique structure of this compound includes an allyl group and a hydrazine moiety, providing diverse reactivity options that can be exploited in organic synthesis.
  • Biological Potential: Compounds containing hydrazine derivatives have been noted for their significant biological activities, including anti-tumor and anti-inflammatory properties. Researchers constantly explore the pharmacological potential of such structures.
  • Research Interest: The hexahydropyrimidine backbone serves as a core framework for many drug candidates. Due to its ability to form hydrogen bonds, it can interact effectively with biological targets.
  • Synthetic Challenges: The synthesis of such complex molecules poses notable challenges in organic chemistry, making them subjects of interest for synthetic methodology development. Innovations in synthesis techniques continue to enhance accessibility to such compounds.
  • Application in Drug Development: The exploration of this compound could lead to the development of new pharmacological agents or repurposing of existing drugs with improved efficacy and safety profiles.

As noted in various studies, “Compounds like 5-allyl-5-(2-hydrazinylidenepropyl)hexahydropyrimidine-2,4,6-trione exhibit novel biological activities that warrant further exploration.” Understanding the nuances of their mechanism of action might open new avenues in therapeutics.

In conclusion, the ongoing research into this compound underscores the importance of chemical diversity in the pursuit of innovative solutions to complex biological problems. The captivating world of hexahydropyrimidines offers endless possibilities for future discoveries!