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Primidone

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Identification
Molecular formula
C12H14N2O2
CAS number
125-33-7
IUPAC name
5-allyl-5-phenyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, Primidone is in a solid state. It is stable under normal temperature and pressure conditions.

Melting point (Celsius)
279.00
Melting point (Kelvin)
552.20
Boiling point (Celsius)
437.70
Boiling point (Kelvin)
710.80
General information
Molecular weight
218.26g/mol
Molar mass
218.2570g/mol
Density
1.1424g/cm3
Appearence

Primidone typically appears as a white, crystalline powder. It is odorless and possesses a slightly bitter taste. The compound is sensitive to light and should be stored in a light-resistant container.

Comment on solubility

Solubility of 5-allyl-5-phenyl-hexahydropyrimidine-2,4,6-trione

The solubility of 5-allyl-5-phenyl-hexahydropyrimidine-2,4,6-trione is an intriguing aspect due to its unique structure and functional groups. Understanding its solubility characteristics is essential for applications in pharmaceuticals and organic synthesis. Here are some key points:

  • Polarity: The presence of multiple carbonyl groups can contribute to polarity, influencing the solubility of this compound in polar solvents.
  • Solvent Compatibility: It is likely to show better solubility in organic solvents such as ethanol and acetone compared to water, given its hydrophobic regions imparted by the hexahydropyrimidine moiety.
  • Hydrogen Bonding: The compound may engage in hydrogen bonding with solvents that can donate or accept hydrogen bonds, enhancing its solubility in specific polar solvents.

In conclusion, the solubility of 5-allyl-5-phenyl-hexahydropyrimidine-2,4,6-trione will largely depend on the interplay between its functional groups and the solvent characteristics, making it a compound of interest for further solubility studies.

Interesting facts

Interesting Facts about 5-allyl-5-phenyl-hexahydropyrimidine-2,4,6-trione

5-allyl-5-phenyl-hexahydropyrimidine-2,4,6-trione is a fascinating compound that showcases the intricate world of organic chemistry. Here are some intriguing aspects of this compound:

  • Structural Intricacies: This compound features a unique hexahydropyrimidine skeleton, highlighting the intricate framework of nitrogen-containing heterocycles.
  • Diverse Applications: Such compounds are often of interest in medicinal chemistry due to their potential biological activity. Their structure allows for various modifications, potentially leading to novel therapeutic agents.
  • Allyl Group Benefits: The presence of the allyl group can enhance reactivity and facilitate further synthetic transformations, making this compound an excellent precursor in organic synthesis.
  • Phenyl Influence: The phenyl group can significantly affect the stability and reactivity of the compound, often impacting its electronic properties and interactions with other molecules.
  • Catalytic Potential: Compounds like this are often studied for their catalytic properties, particularly in the formation of C–C bonds, which are pivotal in complex organic synthesis.

In summary, 5-allyl-5-phenyl-hexahydropyrimidine-2,4,6-trione exemplifies the richness of organic compounds and their potential in various fields, from pharmaceuticals to materials science. As chemistry students and scientists delve into the study of such compounds, they uncover a treasure trove of chemical behavior, application, and potential.

Synonyms
Phenallymal
Alphenal
Alpheba
Allofenyl
Alphenate
Fenallymal
Phenallymalum
Prophenal
Allophenylum
Alphasem
115-43-5
Tubergal
5-Allyl-5-phenylbarbituric acid
5-Phenyl-5-allylbarbituric acid
BARBITURIC ACID, 5-ALLYL-5-PHENYL-
5-Allyl-5-phenylbarbitursaeure
Acido 5-fenil-5-allilbarbiturico
EINECS 204-089-9
BRN 0227510
7T7L08Q9JI
5-phenyl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
Acido 5-fenil-5-allilbarbiturico [Italian]
PHENALLYMAL [MI]
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-phenyl-5-(2-propenyl)-
5-Phenyl-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
DTXSID60150919
5-24-09-00334 (Beilstein Handbook Reference)
Dorlotin
Luxomnin
Alphenal (1mg/ml in Acetonitrile)
UNII-7T7L08Q9JI
SCHEMBL715099
5-allyl-5-phenylpyrimidine-2,4,6(1h,3h,5h)-trione
DTXCID9073410
CHEBI:134993
STK299181
AKOS003382444
5-ALLYL-5-PHENYL-BARBITURIC ACID
NS00023739
Q414954
SR-01000883751
SR-01000883751-1
5-Allyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione #
5-phenyl-5-(prop-2-en-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-phenyl-5-(2-propenyl)-(9CI)
204-089-9