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Thiopental

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Identification
Molecular formula
C11H18N2O2S
CAS number
76-75-5
IUPAC name
5-allyl-5-sec-butyl-2-sulfanyl-1H-pyrimidine-4,6-dione
State
State
At room temperature, thiopental is a solid compound. It is often provided in its sodium salt form which is used as an injectable liquid solution in medical applications.
Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
264.35g/mol
Molar mass
264.3560g/mol
Density
1.2800g/cm3
Appearence

Thiopental is typically found as a white crystalline powder. It is highly soluble in water and has a slightly bitter taste.

Comment on solubility

Solubility of 5-allyl-5-sec-butyl-2-sulfanyl-1H-pyrimidine-4,6-dione

The solubility of 5-allyl-5-sec-butyl-2-sulfanyl-1H-pyrimidine-4,6-dione can be quite intriguing due to its unique structure. Understanding the solubility characteristics of this compound can help in predicting its behavior in various environments.

Factors Influencing Solubility

  • Polarity: Compounds that exhibit significant polar functional groups typically have enhanced solubility in polar solvents, such as water.
  • Hydrogen Bonding: If a compound can form hydrogen bonds with the solvent, it may dissolve more readily.
  • Alkyl Chains: The presence of long alkyl chains, like sec-butyl in this molecule, often increases hydrophobicity and can reduce solubility in polar solvents.

As for 5-allyl-5-sec-butyl-2-sulfanyl-1H-pyrimidine-4,6-dione, its specific solubility is influenced by the balance between its polar pyrimidine ring and less polar alkyl substituents. It is likely to have moderate solubility in organic solvents but lower solubility in aqueous environments, making it suitable for applications that require stability in non-polar media.

General Observations

  • If you're considering this compound for synthesis or formulation, it's advisable to test its solubility in a range of solvents to identify the best candidates.
  • Experimental data will be crucial, as theoretical predictions can only provide a framework.

In conclusion, the solubility of 5-allyl-5-sec-butyl-2-sulfanyl-1H-pyrimidine-4,6-dione is dictated by its structural features, and careful experimentation will yield the most relevant insights into its behavior in different solvents.

Interesting facts

Interesting Facts about 5-allyl-5-sec-butyl-2-sulfanyl-1H-pyrimidine-4,6-dione

The compound 5-allyl-5-sec-butyl-2-sulfanyl-1H-pyrimidine-4,6-dione is a fascinating member of the pyrimidine family, characterized by its unique structure and various applications. Here are some compelling insights:

  • Structural diversity: This compound features a pyrimidine nucleus that is substituted at specific positions, showcasing the versatility of heterocyclic compounds. The presence of both allyl and sec-butyl groups enhances its structural complexity, which can lead to varied chemical reactivity.
  • Biological significance: Compounds with pyrimidine rings have been widely studied for their biological activities. They play vital roles in medicinal chemistry, as they are often found in pharmaceuticals and agrochemicals. Their derivatives have shown potential in treating various diseases, including cancer and bacterial infections.
  • Sulfur incorporation: The presence of a sulfanyl group (–SH) in the structure contributes to the compound's unique chemical properties, such as increased reactivity and the potential to form diverse coordination complexes. Sulfur-containing compounds are often known for their ability to act as antioxidants.
  • Research potential: Given its complex architecture, this compound presents numerous opportunities for further research. Scientists may explore its synthesis pathways, reactivity profiles, and potential applications in areas such as organic synthesis and material science.
  • Pharmacological interest: There is an ongoing interest in modifying the compound to enhance its efficacy or reduce side effects, making it a candidate for drug development. Its unique combinations of functional groups may lead to novel biological activities that are yet to be explored.

In summary, 5-allyl-5-sec-butyl-2-sulfanyl-1H-pyrimidine-4,6-dione stands as a testament to the intriguing world of organic chemistry. With its varied implications in medicinal applications and its unique structural traits, this compound is undoubtedly of great interest to researchers and chemists alike.