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Nile blue

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Identification
Molecular formula
C20H20N3O
CAS number
3625-57-8
IUPAC name
(5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium
State
State

At room temperature, Nile blue is a solid compound, typically used in its powdered form for dyes and staining.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
288.75g/mol
Molar mass
288.7520g/mol
Density
1.5400g/cm3
Appearence

Nile blue is a dark blue to black powder. It is often used as a biological stain in microscopy, emphasizing contrast in cells and tissues.

Comment on solubility

Solubility of (5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium

The solubility of the compound (5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium is influenced by several factors due to its unique structural features. This compound is categorized as a quaternary ammonium salt, which typically exhibits certain solubility characteristics:

  • Hydrophilicity: The presence of the dimethyl-ammonium group often enhances solubility in polar solvents, particularly water.
  • Solvent Compatibility: It tends to dissolve well in organic solvents such as methanol and ethanol, while showing varied solubility in less polar solvents.
  • Temperature Influence: As with many compounds, an increase in temperature can significantly enhance solubility in aqueous solutions.
  • pH Sensitivity: The solubility may also vary with pH; in more alkaline conditions, the compound might exhibit improved solubility due to deprotonation processes.

In summary, while the compound has a greater tendency to dissolve in polar solvents, its solubility can be affected by factors such as temperature and pH. Understanding these factors is critical for applications in various fields, including medicinal chemistry and materials science.

Interesting facts

Interesting Facts about (5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium

This intriguing compound belongs to a family known as phenoxazines, which have garnered attention for their various applications in the fields of biology, medicine, and materials science. Here are some captivating highlights about this compound:

  • Biological Significance: Compounds in the phenoxazine class are often studied for their potential as fluorescent dyes and therapeutic agents. The presence of an amino group contributes to its ability to interact with biological molecules, which might lead to significant implications in drug development.
  • Fluorescence: The unique structure of this compound allows it to exhibit fluorescence, a property that makes it valuable in bioimaging techniques. Researchers utilize these properties to track cellular activities in real-time.
  • Structural Diversity: The incorporation of a methyl group at the 10-position adds to the diversity of phenoxazines, enhancing their chemical stability and influencing their interactions in biological environments.
  • Potential Applications: Due to its unique electronic structure, this compound holds promise in applications such as sensors, photovoltaics, and catalysts for various chemical reactions.
  • Synthesis Challenges: The synthesis of this compound can be intricate, often involving multi-step chemical reactions. Chemists harness advanced techniques in organic synthesis to create such compounds, showcasing the art and science of chemistry.
  • Interdisciplinary Interest: This compound attracts interest from various fields—including organic chemistry, pharmacology, and materials science—demonstrating the interconnected nature of scientific research.

The exploration of compounds like (5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium not only enriches our understanding of chemistry but also opens avenues for innovative solutions in various scientific disciplines. As researchers continue to investigate the properties and applications of such compounds, we may witness groundbreaking advancements that harness their unique capabilities.