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Nile Blue A

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Identification
Molecular formula
C20H20N3OCl
CAS number
3625-57-8
IUPAC name
(5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium;chloride
State
State

At room temperature, Nile Blue A is typically a solid. It appears as a vibrant blue powder or crystal, primarily utilized due to its solubility in water and ability to provide contrast in laboratory staining applications.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
342.85g/mol
Molar mass
342.8450g/mol
Density
1.1001g/cm3
Appearence

This compound appears as a dark blue to purple crystalline solid. It is often used as a stain in biological applications, highlighting cellular components under a microscope due to its intense coloration.

Comment on solubility

Solubility of (5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium;chloride

The solubility of the compound (5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium;chloride can be influenced by several key factors that are crucial to its behavior in various solvents. Here are some salient points regarding its solubility:

  • Water Solubility: The presence of the quaternary ammonium group in the molecule suggests that it is likely to exhibit good solubility in polar solvents such as water. This can be attributed to ionic interactions and hydrogen bonding.
  • Solvent Choice: While it may be soluble in water, its solubility could also vary in organic solvents. For instance, alcohols like methanol or ethanol could exhibit moderate solubility.
  • pH Dependency: The solubility may show sensitivity to pH changes, given the presence of amino groups, which can ionize and enhance solubility in acidic or basic environments.
  • Temperature Influence: As with many compounds, increased temperature can lead to enhanced solubility, allowing for more effective dissolution.
  • Selectivity in Solutions: The compound might demonstrate selective solubility; thus, it may behave differently in mixed solvents or when interacting with other chemicals.

In conclusion, while the potential for solubility in aqueous environments appears promising due to the ionic nature of the compound, exploration in various solvents and conditions will provide a clearer picture of its solubility profile. Understanding these solubility characteristics is essential for applications in various fields, including pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts about (5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium;chloride

This fascinating compound, known as (5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium;chloride, has a variety of intriguing applications in the field of chemistry and materials science. Here are some key points to consider:

  • Fluorescent Properties: Some derivatives of phenoxazines are known to exhibit strong fluorescence, making them valuable in biological imaging and as fluorescent probes.
  • Biological Applications: Compounds like this may possess antimicrobial or anticancer properties, offering avenues for therapeutic exploration.
  • Dye Chemistry: The structure of this compound suggests potential use as a dye or pigment, due to its chromophoric characteristics.
  • Ammonium Ion Dynamics: The presence of the dimethylammonium cation can significantly influence the solubility and interaction of the compound with biomolecules, thereby affecting its potential biological activity.
  • Research Significance: Compounds with such structures often lead to important developments in organic synthesis and medicinal chemistry, serving as precursors or intermediates in larger chemical syntheses.

As a scientist studying such compounds, it is crucial to explore their structure-activity relationships and the impact of various substituents on their properties. The versatility of these compounds opens up a plethora of research opportunities, making them a significant focus in contemporary chemical studies.

Overall, (5-amino-10-methyl-benzo[a]phenoxazin-9-ylidene)-dimethyl-ammonium;chloride stands out as a compound with multifaceted potential both in laboratory applications and in future innovations within various scientific fields.

Synonyms
Cresyl violet
18472-89-4
2AB49C465R
5-Amino-9-(dimethylamino)-10-methylbenzo[a]phenoxazin-7-ium chloride
(5-amino-10-methylbenzo[a]phenoxazin-9-ylidene)-dimethylazanium;chloride
Cresole Violet
5-Amino-9-(dimethylamino)-10-methylbenzo(a)phenoxazin-7-ium chloride
EINECS 242-356-1
UNII-2AB49C465R
5H-Benzo(a)phenoxazin-9-amine, 5-imino-N,N,10-trimethyl-, monohydrochloride
9-(Dimethylamino)-5-imino-10-methyl-5H-benzo(a)phenoxazine hydrochloride
SCHEMBL609206
SCHEMBL25265896
DTXSID10939892
ABASSERKNXVFAX-UHFFFAOYSA-M
Benzo(a)phenoxazin-7-ium, 5-amino-9-(dimethylamino)-10-methyl-, chloride
5H-BENZO(a)PHENOXAZINE, 9-(DIMETHYLAMINO)-5-IMINO-10-METHYL-, MONOHYDROCHLORIDE
NS00052281
Q5184693
BENZO(A)PHENOXAZIN-7-IUM, 5-AMINO-9-(DIMETHYLAMINO)-10-METHYL-, CHLORIDE (1:1)