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5-Amino-1,3,4-thiadiazole-2-thiol

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Identification
Molecular formula
C2H3N3S2
CAS number
2349-67-9
IUPAC name
5-amino-1,3,4-thiadiazole-2-thiol
State
State

At room temperature, 5-Amino-1,3,4-thiadiazole-2-thiol is a solid. It maintains its stability and form, making it manageable for storage and handling in various chemical processes or laboratory settings.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.00
Boiling point (Celsius)
279.00
Boiling point (Kelvin)
552.00
General information
Molecular weight
133.18g/mol
Molar mass
133.1810g/mol
Density
1.9810g/cm3
Appearence

5-Amino-1,3,4-thiadiazole-2-thiol typically appears as a light-yellow crystalline solid that is visually distinctive due to its color and crystalline form. As a solid, it is characterized by its homogenous and stable appearance, which is common for many thiadiazole derivatives. The compound is often in the form of fine crystals or powder.

Comment on solubility

Solubility of 5-amino-1,3,4-thiadiazole-2-thiol

The solubility of 5-amino-1,3,4-thiadiazole-2-thiol can be influenced by several factors including its molecular structure and the environment in which it is analyzed. This compound is characterized by the presence of both amino (-NH2) and thiol (-SH) functional groups, which can significantly affect its solubility properties.

  • Polarity: The presence of polar groups typically enhances solubility in polar solvents such as water.
  • Hydrogen Bonding: The amino group can participate in hydrogen bonding, leading to better solubility in aqueous solutions.
  • pH Dependence: The solubility may vary with pH due to ionization of the thiol group, where lower pH can increase solubility.

However, due to its unique structure, 5-amino-1,3,4-thiadiazole-2-thiol may exhibit moderate to low solubility in non-polar solvents. As a result, it is crucial to note:

  1. Solubility increases with the addition of polar solvents.
  2. Solubility can be impacted by temperature; increased temperature may lead to higher solubility.
  3. Evaluation of solubility should consider both water and organic solvent interactions.

In summary, understanding the solubility characteristics of 5-amino-1,3,4-thiadiazole-2-thiol requires a comprehensive assessment of its molecular interactions and environmental conditions, ultimately affecting its practical applications.

Interesting facts

Interesting Facts About 5-Amino-1,3,4-thiadiazole-2-thiol

5-Amino-1,3,4-thiadiazole-2-thiol is a remarkable compound with diverse applications in various fields, including pharmaceuticals and agrochemicals. Here are some intriguing aspects of this compound:

  • Biological Activity: This compound exhibits significant biological activities, including antimicrobial and antifungal properties, making it a potential candidate for developing new antibiotics and antifungal agents.
  • Versatile Building Block: It serves as an essential building block in the synthesis of more complex organic compounds, particularly in the design of novel drugs, due to the presence of both amino and thiol functional groups.
  • Inhibition Mechanism: Studies have shown that 5-amino-1,3,4-thiadiazole-2-thiol can inhibit various enzymes, which is crucial in understanding its role in drug design and the development of therapeutic agents.
  • Environmental Relevance: Due to its unique thiadiazole structure, this compound may also play a role in the development of eco-friendly pesticides, providing an alternative approach to reducing chemical impacts on the environment.

In summary, 5-amino-1,3,4-thiadiazole-2-thiol is not just an ordinary chemical compound; it is a multifaceted substance with substantial implications in health and the environment. Its exploration can pave the way for innovative solutions in science and technology.