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Sulfanilic acid

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Identification
Molecular formula
C6H7NO4S
CAS number
121-57-3
IUPAC name
5-amino-2-hydroxy-3-sulfo-benzoic acid
State
State

At room temperature, sulfanilic acid is a solid. It exists in crystalline form.

Melting point (Celsius)
288.00
Melting point (Kelvin)
561.00
Boiling point (Celsius)
314.00
Boiling point (Kelvin)
587.00
General information
Molecular weight
173.16g/mol
Molar mass
173.1590g/mol
Density
2.0490g/cm3
Appearence

Sulfanilic acid typically appears as a white to yellowish crystalline powder. It may also appear as small shiny crystals.

Comment on solubility

Solubility of 5-amino-2-hydroxy-3-sulfo-benzoic acid

5-amino-2-hydroxy-3-sulfo-benzoic acid, often referred to as an amino acid derivative, possesses unique solubility characteristics that merit attention. Its solubility in various solvents can be attributed to several structural features:

  • Functional Groups: The presence of amino, hydroxy, and sulfo groups enhances its ability to interact with water molecules, promoting hydrophilicity.
  • pH Dependency: The solubility of this compound can vary significantly with pH. At lower pH levels, it may exist primarily in its protonated form, which can further increase solubility.
  • Temperature Influence: As with many organic acids, the solubility is also temperature-dependent. Increased temperatures typically improve its solubility in aqueous solutions.

In summary, the solubility of 5-amino-2-hydroxy-3-sulfo-benzoic acid is significantly influenced by:

  1. Presence of polar functional groups
  2. Environmental pH
  3. Temperature changes

Understanding these factors is crucial for its application in various fields, including biochemistry and pharmaceuticals, where solubility plays a fundamental role in the behavior of chemicals in biological systems. Remember, solubility is not just a property but a dynamic characteristic that influences the efficacy and functionality of compounds like 5-amino-2-hydroxy-3-sulfo-benzoic acid.

Interesting facts

Exploring 5-Amino-2-hydroxy-3-sulfo-benzoic Acid

5-Amino-2-hydroxy-3-sulfo-benzoic acid is an intriguing compound with several notable attributes and applications that would pique the interest of any chemist or aspiring student. This compound belongs to the class of amino acids and benzenesulfonic acids, which adds a unique dimension to its chemical reactivity and functionality.

Key Features

  • Biological Significance: It serves as an important building block in the synthesis of various biological molecules, playing a critical role in metabolic pathways.
  • pH Regulation: The hydroxyl (-OH) and amino (-NH2) groups contribute to its ability to act as a buffer in biological systems.
  • Synthesis Potential: As a sulfonated derivative, this compound provides enhanced solubility in water, making it valuable in pharmaceutical applications.
  • Industrial Uses: It can be employed in dye manufacturing, where its specific functional groups can form bonds with various substrates.

The structural configuration of 5-amino-2-hydroxy-3-sulfo-benzoic acid allows it to participate in multiple chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions, making it a versatile compound in organic synthesis.
This compound is not just limited to lab use; it also finds its place in various industrial activities and can be used to create products with desirable properties. As a chemist, understanding the behavior and applications of such compounds can lead to innovative solutions in drug design and material science.

Conclusion

In summary, 5-amino-2-hydroxy-3-sulfo-benzoic acid exemplifies how seemingly simple compounds can have profound implications across multiple fields of science. The versatility, biological relevance, and industrial applications make it a compound worth studying and appreciating.

Synonyms
5-AMINO-3-SULFOSALICYLIC ACID
6201-87-2
5-amino-2-hydroxy-3-sulfobenzoic acid
5-Amino-3-sulphosalicylic acid
Benzoic acid, 5-amino-2-hydroxy-3-sulfo-
CCRIS 3919
EINECS 228-262-3
NSC 16207
DTXSID0024507
DTXCID204507
3-Amino-6-hydroxy-5-sulfobenzoic acid
Benzoic acid, 5-amino-2-hydroxy-3-sulfo-(9CI)
228-262-3
Salicylic acid, 5-amino-3-sulfo-
NSC-16207
NSC16207
L7ALQ6NHL8
5-Amino-3-sulfo-salizylsaure
SCHEMBL342398
CHEMBL144614
Amino-3-sulfosalicylic acid, 5-
MLPWLRUWQJVULT-UHFFFAOYSA-N
Tox21_201016
5-amino-2-hydroxy-3-sulfobenzoicacid
AKOS024332329
NCGC00091849-01
NCGC00091849-02
NCGC00258569-01
CAS-6201-87-2
NS00034892