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Luminol

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Identification
Molecular formula
C8H7N3O2
CAS number
521-31-3
IUPAC name
5-amino-2,3-dihydrophthalazine-1,4-dione
State
State

At room temperature, luminol exists in a solid state, typically as a crystalline powder. It is stable under normal conditions but requires an oxidizing agent to exhibit its chemiluminescent properties.

Melting point (Celsius)
319.30
Melting point (Kelvin)
592.50
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
177.16g/mol
Molar mass
177.1550g/mol
Density
1.3950g/cm3
Appearence

Luminol is characterized as a white to slightly yellow crystalline powder. When you dissolve it in a suitable solvent and expose it to an oxidizing agent like hydrogen peroxide, it emits a blue glow, which is distinct and commonly used in forensic applications to detect blood traces.

Comment on solubility

Solubility of 5-amino-2,3-dihydrophthalazine-1,4-dione

5-amino-2,3-dihydrophthalazine-1,4-dione, with its unique molecular structure, offers interesting insights into its solubility properties. Generally, the solubility of this compound can be influenced by several factors, including:

  • Polarity: The presence of amino groups in the structure increases polarity, which can enhance solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds may allow 5-amino-2,3-dihydrophthalazine-1,4-dione to dissolve more readily in water compared to non-polar solvents.
  • Temperature: Like many organic compounds, solubility may also improve with an increase in temperature, allowing greater interaction with solvent molecules.
  • pH Levels: The solubility might vary with pH changes, as protonation or deprotonation of the amino group could affect its solubility in aqueous solutions.

In conclusion, the solubility of 5-amino-2,3-dihydrophthalazine-1,4-dione is a complex interplay of structure, solvent characteristics, and external conditions. It can potentially dissolve well in various polar solvents due to its functional groups, making it a compound with promising applications in various fields.

Interesting facts

Interesting Facts about 5-Amino-2,3-dihydrophthalazine-1,4-dione

5-Amino-2,3-dihydrophthalazine-1,4-dione, often referred to as a derivative of phthalazine, holds notable significance in the realm of chemical research and pharmaceutical applications. This compound is characterized by the presence of an amine group, which imparts unique reactivity and functionality, making it a subject of interest in various studies.

Key Features and Applications

  • Pharmaceutical Potential: Compounds similar to 5-amino-2,3-dihydrophthalazine-1,4-dione show promise in drug development, particularly in the field of anti-inflammatory and analgesic agents.
  • Structure-Activity Relationship (SAR): Researchers conduct SAR studies on this compound to explore how structural variations can alter its biological activity, potentially leading to the design of more effective pharmaceuticals.
  • Synthesis Techniques: The synthesis of this compound often involves various organic reactions, and mastering these techniques is essential for budding chemists.

Chemical Insights

This compound is not just interesting due to its biological applications, but it also serves as a valuable intermediate in the synthesis of more complex molecules. Here are a few scientific insights:

  • Reactivity: The amino group can participate in various chemical reactions, including substitution and coupling reactions, which are essential in the synthesis of dyes and other organic compounds.
  • Coordination Chemistry: Due to its ability to form chelates, this compound may be studied in coordination chemistry, opening doors to new complex formations with metal ions.
  • Environmental Chemistry: Investigating the environmental impact and degradation pathways of such compounds is crucial as they can sometimes enter ecosystems through pharmaceutical waste.

In summary, 5-amino-2,3-dihydrophthalazine-1,4-dione serves as a fascinating example of how modifications in molecular structure can lead to enhanced functionalities. As scientists continue to examine its properties and potential applications, the compound underscores the importance of molecular diversity in chemistry.

Synonyms
LUMINOL
521-31-3
5-Amino-2,3-dihydro-1,4-phthalazinedione
3-Aminophthalic hydrazide
3-Aminophthalylhydrazide
NSC 5064
CCRIS 5962
EINECS 208-309-4
UNII-5EXP385Q4F
5EXP385Q4F
DTXSID5024504
AI3-52555
1,2-Benzenedicarboxylic acid, 3-amino-, cyclic hydrazide
NSC-5064
DTXCID004504
3-Aminophthalhydrazide
5-amino-2,3-dihydrophthalazine-1,4-dione
1,4-Phthalazinedione, 5-amino-2,3-dihydro-
5-Amino-1,2,3,4-tetrahydrophthalazine-1,4-dione
3-Aminophthalic acid hydrazide
MFCD00006890
5-Amino-2,3-dihydro-phthalazine-1,4-dione
3-AMINOPHTHALHYDRAZINE
5-aminophthalazine-1,4-diol
MLS002637790
CHEMBL442329
NSC5064
o-aminophthalylhydrazide
o-Aminophthaloyl hydrazide
5-Amino-2,3-dihydro-1,4-phthalazinedone
Luminol, 97%
monosodium-alpha-luminol
3-Aminophthaloylhydrazine
LUMINOL [MI]
Luminol, SAJ special grade
Oprea1_698774
Oprea1_819727
SCHEMBL20086
5-amino-1,4-phthalazinediol
1, 5-amino-2,3-dihydro-
Luminol, >=97% (HPLC)
1, 3-amino-, cyclic hydrazide
3-Aminophthalhydrazide (Luminol)
5-Amino-1,4-dihydroxyphthalazine
HMS3093K04
ALBB-019203
BCP18652
PXB93196
STR04818
Tox21_200940
BBL002758
BDBM50125759
HB0796
s6819
STK138069
STL280212
AKOS000111313
AKOS002945870
AKOS016399881
FL06675
Luminol - for Western Blot and ELISA
SDCCGMLS-0065581.P001
8-amino-4-hydroxyphthalazin-1(2h)-one
5-amino-4-hydroxyphthalazin-1(2H)-one
NCGC00091452-01
NCGC00091452-02
NCGC00258494-01
AC-13306
AC-33248
CAS-521-31-3
FL171930
HY-15922
SMR001547307
SY011102
A5301
EU-0066798
NS00032429
EN300-16893
Luminol, for chemiluminescence, >=98.0% (HPLC)
Q408061
SR-01000389300
5-Amino-1,2,3,4-tetrahydro-1,4-phthalazinedione
SR-01000389300-1
BRD-K52559566-001-01-1
BRD-K52559566-001-02-9
Z56813244
F1313-0002
InChI=1/C8H7N3O2/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12/h1-3H,9H2,(H,10,12)(H,11,13