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Congo Red

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Identification
Molecular formula
C32H22N6O6S2Na2
CAS number
573-58-0
IUPAC name
5-amino-3-[4-[4-[(8-amino-1-hydroxy-3,6-disulfo-2-naphthyl)azo]-3-methyl-phenyl]-2-methyl-phenyl]azo-4-hydroxy-naphthalene-2,7-disulfonic acid
State
State

Congo Red is generally found in a solid state at room temperature. It is often used as a powdered dye for fabrics and some histological dyes in laboratories.

Melting point (Celsius)
360.00
Melting point (Kelvin)
633.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
696.67g/mol
Molar mass
696.6650g/mol
Density
0.9130g/cm3
Appearence

Congo Red is a vibrant, synthetic, organic dye. It typically appears as a reddish-brown powder. In solution, it exhibits a distinct red to blue transition at varying pH levels.

Comment on solubility

Solubility of 5-amino-3-[4-[4-[(8-amino-1-hydroxy-3,6-disulfo-2-naphthyl)azo]-3-methyl-phenyl]-2-methyl-phenyl]azo-4-hydroxy-naphthalene-2,7-disulfonic acid

The compound C32H22N6O6S2Na2, known for its complex structure, exhibits interesting solubility characteristics that are influenced by the presence of sulfonic acid groups. Here are some key points:

  • Highly Water-Soluble: Due to the multiple sulfonic acid groups (-SO3H) in its structure, this compound is expected to be highly soluble in water.
  • Effect of Ionic Strength: The sodium ions (Na+) help increase the solubility in aqueous solutions by reducing the attractive forces between the molecules.
  • pH Sensitivity: The solubility may vary with pH; at different pH levels, the ionization state of the sulfonic acid groups will affect its overall solubility.
  • Interactions with Solvents: It might also exhibit limited solubility in organic solvents due to its polar nature.

In summary, the solubility profile of this compound highlights the influence of functional groups, where the presence of multiple sulfonic acid groups significantly enhances its water solubility.

Interesting facts

Interesting Facts about 5-Amino-3-[(4-[4-[(8-amino-1-hydroxy-3,6-disulfo-2-naphthyl)azo]-3-methyl-phenyl]-2-methyl-phenyl]azo-4-hydroxy-naphthalene-2,7-disulfonic acid

This complex compound, often referred to in the realm of azo dyes, exhibits a myriad of fascinating properties and applications that intrigue both scientists and students alike. Here are some key highlights:

  • Azo Compound Insight: This compound belongs to the family of azo dyes, which are characterized by the presence of a nitrogen-nitrogen (N=N) double bond. Azo dyes are widely recognized for their vibrant colors and are utilized extensively in textile dyeing and biological applications.
  • Environmental Considerations: As with many azo compounds, the environmental impact is a significant aspect. While some azo dyes can be toxic, this specific compound has been optimized for lower toxicological profiles, promoting safer use in various fields.
  • Biological Applications: This compound has shown promise in biomedical research, particularly in drug delivery systems, due to its ability to undergo azo-group cleavage under specific conditions, which may release bioactive components precisely where needed in the body.
  • Synthetic Versatility: The synthesis of this compound highlights the intricate processes in organic chemistry, showcasing methods such as azo coupling and sulfonation, which are fundamental reactions in dye chemistry.
  • Historical Relevance: Azo dyes have had a profound impact on industries, being some of the first synthetic dyes. Their discovery dates back to the 19th century, marking a significant shift from natural dyes to synthetic alternatives.

In summary, 5-amino-3-[(4-[4-[(8-amino-1-hydroxy-3,6-disulfo-2-naphthyl)azo]-3-methyl-phenyl]-2-methyl-phenyl]azo-4-hydroxy-naphthalene-2,7-disulfonic acid is not just a compound of chemical interest, but a remarkable example of the intersection of chemistry, biology, and environmental science. Its multifaceted use and understanding reflect the depth and breadth of research possibilities within the field of azo dyes.

Synonyms
Trypan Blue free acid
TRYPAN BLUE
Niagara Blue 3B
2538-83-2
Trypane Blue
768N7QO4KH
CHEBI:78900
Diamineblue
Dianilblau
Pyrotropblau
Parkibleu
Parkipan
Bleu diamine
Chloramine Blue
Tripan Blue
Benzaminblau 3B
Chloramiblau 3B
Azirdinblau 3B
Bleu trypane N
Benzanil Blue R
Diaminblau 3B
Directblau 3B
Triazolblau 3BX
Benzoblau 3B
Congoblau 3B
Dianilblau H3G
Renolblau 3B
Bleu directe 3B
Trypan Blue BPC
Amidine Blue 4B
Azidine Blue 3B
Diamine Blue 3B
Diazine Blue 3B
Pyrazol Blue 3B
Bleue diretto 3B
Diazol Blue 3B
Direct Blue 3B
Bencidal Blue 3B
Dianil Blue H3G
Diphenyl Blue 3B
Direct Blue 3BX
Direct Blue D3B
Direct Blue H3G
Direct Blue M3B
Paramine Blue 3B
Azurro diretto 3B
Benzo Blue 3B
Blue EMB
Congo Blue 3B
Naphthaminblau 3BX
Orion Blue 3B
Benzamine Blue 3B
Chlorazol Blue 3B
Cresotine Blue 3B
Amanil Sky Blue R
Benzanil Blue 3BN
Hispamin Blue 3BX
Centraline Blue 3B
Chloramine Blue 3B
Bleu diazole N 3B
Diaphtamine Blue TH
Pontamine Blue 3BX
Blue 3B
Brasilamina Blue 3B
Brasilazina Blue 3B
Directakol Blue 3BL
Naphtamine Blue 3BX
Naphthamine Blue 3BX
Chrome Leather Blue 3B
Trianol Direct Blue 3B
3,3'-((3,3'-Dimethyl-[1,1'-biphenyl]-4,4'-diyl)bis(diazene-2,1-diyl))bis(5-amino-4-hydroxynaphthalene-2,7-disulfonic acid)
NSC11247
trypan blue acid
C.I. Direct Blue
trypan blue sulfonic acid
UNII-768N7QO4KH
C.I. Direct Blue 14 parent
CHEMBL1089641
CHEMBL1206040
DTXSID8048313
SCHEMBL12234090
SCHEMBL15497820
ZBNARPCCDMHDDV-UHFFFAOYSA-N
DB09158
EN300-28265993
Q419642
2,7-NAPHTHALENEDISULFONIC ACID, 3,3'-((3,3'-DIMETHYL(1,1'-BIPHENYL)-4,4'-DIYL)BIS(AZO))BIS(5-AMINO-4-HYDROXY-
2,7-Naphthalenedisulfonic acid, 3,3'-[(3,3'-dimethyl-4,4'-biphenylylene)bis(azo)]bis(5-amino-4-hydroxy-
3,3'-[(3,3'-dimethylbiphenyl-4,4'-diyl)didiazene-2,1-diyl]bis(5-amino-4-hydroxynaphthalene-2,7-disulfonic acid)
5-amino-3-[(1E)-2-{4'-[(1E)-2-(8-amino-1-hydroxy-3,6-disulfonaphthalen-2-yl)diazen-1-yl]-3,3'-dimethyl-[1,1'-biphenyl]-4-yl}diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonic acid
5-amino-3-[(E)-[4-[4-[(E)-(8-amino-1-hydroxy-3,6-disulfo-2-naphthyl)azo]-3-methyl-phenyl]-2-methyl-phenyl]azo]-4-hydroxy-naphthalene-2,7-disulfonic acid
5-amino-3-[[4-[4-[(8-amino-1-hydroxy-3,6-disulfonaphthalen-2-yl)diazenyl]-3-methylphenyl]-2-methylphenyl]diazenyl]-4-hydroxynaphthalene-2,7-disulfonic acid