Skip to main content

Dorzolamide

ADVERTISEMENT
Identification
Molecular formula
C10H10N4O4S3
CAS number
120279-96-1
IUPAC name
5-(benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide
State
State

At room temperature, Dorzolamide is typically found in a solid state when isolated. It is commonly available as a component in ophthalmic solutions in pharmaceuticals.

Melting point (Celsius)
264.00
Melting point (Kelvin)
537.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
324.41g/mol
Molar mass
324.4050g/mol
Density
1.6000g/cm3
Appearence

Dorzolamide, often appearing as Dorzolamide Hydrochloride in medications, typically presents as a white to off-white crystalline powder. As a raw compound, it can also appear as a solid in its isolated form.

Comment on solubility

Solubility of 5-(benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide

The solubility of 5-(benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide, a complex chemical compound, can be quite intriguing due to its specific structural features. Generally, the solubility characteristics of such compounds can be influenced by multiple factors including:

  • Polarity: The presence of sulfonamide groups makes this compound moderately polar, which can enhance its solubility in polar solvents.
  • Hydrogen Bonding: The functional groups can form hydrogen bonds with water, contributing to favorable solubility.
  • Temperature: Like many compounds, its solubility may increase with temperature, allowing for greater dissolution in various solvents.
  • pH Levels: The solubility may also be affected by the pH of the solution, particularly due to the sulfonamide group, which can ionize depending on the pH.

In conclusion, while 5-(benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide displays solubility in polar solvents such as water, factors like temperature, acidity/alkalinity, and the overall molecular structure play crucial roles in determining its specific solubility profile. For a clearer understanding, lab experiments can provide quantitative data on its solubility behavior in various environments.

Interesting facts

Interesting Facts about 5-(Benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide

5-(Benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide, a sulfonamide compound, boasts several intriguing characteristics that highlight its significance in the field of chemistry and medicinal science. Here are some key points to consider:

  • Antibacterial Properties: This compound is notable for its **antimicrobial potential**. Sulfonamides like this one have played a vital role in the development of antibiotics, marking a significant advancement in medical chemistry.
  • Structural Uniqueness: The thiadiazole ring present in its structure introduces remarkable chemical properties, allowing it to participate in various reactions and making it a versatile compound in synthetic chemistry.
  • Application in Pharmaceuticals: Compounds of this nature are often used as building blocks for designing new drugs, especially in the treatment of bacterial infections and certain types of cancer.
  • Research and Development: Ongoing studies are aimed at enhancing the efficacy and reducing the side effects of sulfonamide derivatives, contributing to the extensive field of **medicinal chemistry**.
  • Drug Resistance Challenges: As with many antibiotics, researchers are continuously investigating how structures similar to this compound can overcome issues related to drug resistance, making this compound a topic of interest in pharmacological research.

As we explore the applications and implications of 5-(benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide, we gain insights into the **dynamic interplay of structure and function** in chemical compounds. This highlights the importance of chemical research in developing solutions for health challenges faced by society today.

Synonyms
BENZOLAMIDE
3368-13-6
5-(benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide
CL 11366
1,3,4-Thiadiazole-2-sulfonamide, 5-((phenylsulfonyl)amino)-
FC5AAH89R5
1,3,4-Thiadiazole-2-sulfonamide, 5-[(phenylsulfonyl)amino]-
W 1803
1,3,4-Thiadiazole-2-sulfonamide, 5-benzenesulfonamido-
2-(Phenylsulfonylamino)-1,3,4-thiadiazole-5-sulfonamide
DTXSID10187356
5-(phenylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide
DTXCID20109847
1,3,4-Thiadiazole-2-sulfonamide, 5-benzenesulfonamido-(6CI)
2-benzenesulfonamido-1,3,4-thiadiazole-5-sulfonamide
5-(phenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide
CHEMBL73962
5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
UNII-FC5AAH89R5
3dbu
D8W
Benzolamide (BZA)
3d8w
BZA1
GTPL6920
SCHEMBL3497931
BDBM10886
EX-A11215
MFCD01750412
AKOS028108395
DB07050
AS-78505
DA-71389
HY-118467
CS-0066040
NS00069833
CL-11366; W-1803
2-N-benzene-1,3,4-thiadiazole-2,5-disulfonamide
A875219
Q27075059