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Olanzapine

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Identification
Molecular formula
C17H20N4S
CAS number
132539-06-1
IUPAC name
5-benzyl-11-(1-methyl-4-piperidylidene)-6H-benzo[c][1]benzazepine
State
State

At room temperature, olanzapine is a solid.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
356.80
Boiling point (Kelvin)
629.95
General information
Molecular weight
312.44g/mol
Molar mass
312.4370g/mol
Density
1.2460g/cm3
Appearence

Olanzapine appears as a white to slightly yellow crystalline powder. It is insoluble in water, sparingly soluble in ethanol, and slightly soluble in methylene chloride.

Comment on solubility

Solubility of 5-benzyl-11-(1-methyl-4-piperidylidene)-6H-benzo[c][1]benzazepine

The solubility of 5-benzyl-11-(1-methyl-4-piperidylidene)-6H-benzo[c][1]benzazepine, a complex organic compound, can be influenced by several factors that are important to consider. Here are some key points regarding its solubility:

  • Solvent Polarity: This compound is likely to exhibit variable solubility in polar versus non-polar solvents. It may dissolve better in non-polar solvents due to its aromatic and hydrophobic structures.
  • Temperature Dependence: Like many organic compounds, the solubility can increase with temperature. Warmer solvents often allow for better dissolution.
  • pH Sensitivity: Being a heterocyclic compound, pH levels can influence solubility. Adjusting the pH may impact ionization states and enhance solubility in certain mediums.
  • Complexation Effects: The presence of other chemical species in solution can affect the solubility through complex formation, potentially enhancing or reducing its solubility.

Overall, understanding the solubility characteristics of this compound is essential for its applications in various fields such as pharmaceuticals and materials science. Comprehensive solubility data can aid in predicting behavior in different environments and contribute to effective formulation strategies.

Interesting facts

Interesting Facts about 5-benzyl-11-(1-methyl-4-piperidylidene)-6H-benzo[c][1]benzazepine

5-benzyl-11-(1-methyl-4-piperidylidene)-6H-benzo[c][1]benzazepine is a fascinating compound with intriguing properties and potential applications. Here are some interesting aspects to consider:

  • Structural Complexity: This compound features a multi-ring structure that includes a benzazepine framework. Such complexity offers unique opportunities for exploring its chemical behavior and interactions.
  • Biological Activity: Compounds belonging to the benzazepine family are often studied for their biological activities. They may exhibit properties such as antidepressant, neuroprotective, or antipsychotic effects, making them of great interest in medicinal chemistry.
  • Drug Development: The presence of a piperidine moiety in its structure suggests potential activity as a ligand for various neuroreceptors, which could lead to the development of new therapeutic agents targeting mental health disorders.
  • Research Potential: Ongoing research into compounds like this one may lead to discoveries of novel treatments for central nervous system (CNS) conditions. Its unique combination of functional groups may offer pathways for creating more effective, targeted drugs.
  • Synthesis Challenges: The synthesis of such complex molecules presents challenges in terms of achieving purity and yield, which are crucial for any practical applications in pharmaceuticals.
  • Interdisciplinary Interest: The study of this compound bridges multiple fields, including organic chemistry, pharmacology, and medicinal chemistry, showcasing the collaborative nature of modern scientific research.

In summary, 5-benzyl-11-(1-methyl-4-piperidylidene)-6H-benzo[c][1]benzazepine is not just a chemical entity but a promising candidate for future innovations in drug discovery. Its structural uniqueness and potential therapeutic applications keep it at the forefront of chemical research.

Synonyms
EX-10-542A free base
95ZK5SF9GY
UNII-95ZK5SF9GY
3297-28-7
5-Benzyl-11-(4-(N-methylpiperidylene))-5,6-dihydromorphanthridine
5H-Dibenz(b,E)azepine, 6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5-(phenylmethyl)-