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5-Benzyloxyindole

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Identification
Molecular formula
C15H13NO
CAS number
1801-45-4
IUPAC name
5-benzyloxy-1H-indole
State
State
Solid at room temperature. The compound often forms stable crystals with a well-defined lattice.
Melting point (Celsius)
106.00
Melting point (Kelvin)
379.15
Boiling point (Celsius)
393.00
Boiling point (Kelvin)
666.15
General information
Molecular weight
237.29g/mol
Molar mass
237.2890g/mol
Density
1.2330g/cm3
Appearence

5-Benzyloxyindole is a light tan to off-white crystalline powder that may appear slightly yellowish depending on its purity and the presence of impurities.

Comment on solubility

Solubility of 5-Benzyloxy-1H-Indole

5-Benzyloxy-1H-indole, with its complex structure and aromatic properties, presents interesting solubility characteristics. The solubility of this compound can be influenced by various factors, including:

  • Polarity: The presence of both the benzyloxy and indole groups contributes to its overall polar and non-polar interactions, suggesting moderate solubility in organic solvents.
  • Solvent Choice: It is generally more soluble in non-polar solvents, such as chloroform or ethanol, rather than in water. This is common in many indole derivatives.
  • Temperature Effects: Solubility can increase with temperature. Higher temperatures often facilitate better dissolution of organic compounds.
  • Crystallization: The compound may also form crystals that can be selectively dissolved in the right solvent mix, enhancing its utility in research and applications.

In summary, understanding the solubility of 5-benzyloxy-1H-indole not only aids in its practical applications but also enriches its study in organic chemistry. As quoted by chemists, "Solubility is often the gateway to understanding a compound's behavior in various environments."

Interesting facts

Interesting Facts About 5-Benzyloxy-1H-Indole

5-Benzyloxy-1H-indole is a fascinating compound that has attracted the attention of chemists and biochemists alike, largely due to its intriguing structure and potential applications. Here are some insightful highlights about this compound:

  • Structural Significance: This compound is derived from indole, a pivotal structure in numerous natural alkaloids and pharmaceuticals. The presence of the benzyloxy group enhances its chemical reactivity and introduces a level of complexity that can be manipulated in synthetic chemistry.
  • Biological Relevance: Indole derivatives, including 5-benzyloxy-1H-indole, are known for their wide range of biological activities. They are being studied for potential applications in medicinal chemistry, particularly in relation to cancer research and antimicrobial activity.
  • Ecosystem Impact: Compounds like this one contribute to the diversity of chemical signals in biological systems. They can play a vital role in plant communication and defense mechanisms, highlighting their ecological importance.
  • Synthetic Routes: The synthesis of 5-benzyloxy-1H-indole can involve various methods, including the use of alkylation or coupling reactions. Such flexibility in synthetic pathways showcases the compound's versatility and the creativity required in modern organic chemistry.
  • Catalytic Activity: There are indications that indole derivatives may exhibit catalytic properties, providing opportunities for their use in sustainable chemistry and green synthesis methodologies.

Overall, 5-benzyloxy-1H-indole exemplifies the interconnection between organic chemistry, material science, and biological applications. Its study not only enhances our understanding of complex organic compounds but also can lead to breakthroughs in drug discovery and environmental science.

Synonyms
5-Benzyloxyindole
1215-59-4
5-(Benzyloxy)-1H-indole
1H-Indole, 5-(phenylmethoxy)-
Benzyloxy-5 indole
INDOLE, 5-BENZYLOXY-
Indole, 5-(benzyloxy)-
5-(phenylmethoxy)indole
Benzyloxy-5 indole [French]
NSC 62895
UNII-YCI4Z02E1C
EINECS 214-930-1
YCI4Z02E1C
5-(Phenylmethoxy)-1H-indole
BRN 0173532
NSC-62895
DTXSID80153285
5-21-03-00019 (Beilstein Handbook Reference)
BENZYL 1H-INDOL-5-YL ETHER
DTXCID6075776
1H-Indole, 5-(phenylmethoxy)-(9CI)
214-930-1
jcqlpdzcnsvbms-uhfffaoysa-n
5-(Benzyloxy)indole
5-phenylmethoxy-1H-indole
MFCD00005676
5-benzoxyindole
5-Benzyloxy-1H-indole
5-benzyloxy indole
5-benzyloxy-indole
5-(Phenylmethoxy)-1H-indole; 5-(Benzyloxy)-1H-indole; 5-Benzyloxyindole; Benzyl 1H-Indol-5-yl Ether; NSC 62895;
5-phenylmethoxyindole
Maybridge3_006788
Oprea1_825327
5-(Benzyloxy)indole, 95%
BIDD:GT0311
SCHEMBL329575
5-(Benzyloxy)-1H-indole #
WLN: T56 BMJ GO1R
CHEMBL1288719
5-[(phenylmethyl)oxy]-1H-indole
A1H32
HMS1450E12
BCP26888
NSC62895
STR00813
BBL010818
STK801770
95% (contains 4% EtOH at maximum)
AKOS000506156
AB00490
CCG-247307
CG-0512
CS-W013088
FB05844
IDI1_018175
NCGC00324807-01
AC-27781
SY004490
DB-012410
B1833
NS00023965
B-1620
AB01320182-02
Q27294452
F0001-2641