Skip to main content

5-benzyloxy-3-(1-methylpyrrolidin-2-yl)-1H-indole

ADVERTISEMENT
Identification
Molecular formula
C20H22N2O
CAS number
158830-85-1
IUPAC name
5-benzyloxy-3-(1-methylpyrrolidin-2-yl)-1H-indole
State
State

At room temperature, this compound is in a solid state. Its physical stability and state can be affected by factors such as temperature and pressure.

Melting point (Celsius)
84.00
Melting point (Kelvin)
357.15
Boiling point (Celsius)
455.00
Boiling point (Kelvin)
728.15
General information
Molecular weight
308.40g/mol
Molar mass
308.3990g/mol
Density
1.2000g/cm3
Appearence

5-Benzyloxy-3-(1-methylpyrrolidin-2-yl)-1H-indole typically appears as a white to off-white powder. The compound is often used in research settings and might also appear as a crystalline solid depending on the sample purity and conditions.

Comment on solubility

Solubility of 5-benzyloxy-3-(1-methylpyrrolidin-2-yl)-1H-indole

The solubility of chemical compounds can significantly influence their applications and effectiveness. In the case of 5-benzyloxy-3-(1-methylpyrrolidin-2-yl)-1H-indole, several factors come into play when assessing its solubility.

Factors Influencing Solubility:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents, while nonpolar regions might push solubility in nonpolar solvents.
  • Hydrogen Bonding: Compounds capable of forming hydrogen bonds often exhibit greater solubility in water and other polar environments.
  • Molecular Size: Larger molecules typically have lower solubility due to steric hindrance and reduced ability to interact favorably with solvent molecules.

The solubility of 5-benzyloxy-3-(1-methylpyrrolidin-2-yl)-1H-indole is anticipated to be influenced by its structural components:

  • The benzyloxy group may impart some degree of lipophilicity, making the compound more soluble in organic solvents.
  • The 1-methylpyrrolidin-2-yl moiety adds an additional layer of complexity, potentially enhancing solubility in diverse environments.

Due to these various structural features, the solubility of 5-benzyloxy-3-(1-methylpyrrolidin-2-yl)-1H-indole may exhibit variable behavior, showing good solubility in organic solvents while being less soluble in aqueous solutions. As with many organic compounds, understanding these solubility characteristics is crucial for predicting their behavior in real-world applications.

Interesting facts

Interesting Facts about 5-Benzyloxy-3-(1-methylpyrrolidin-2-yl)-1H-indole

5-Benzyloxy-3-(1-methylpyrrolidin-2-yl)-1H-indole is a fascinating compound that presents several intriguing characteristics and potential applications:

  • Structural Uniqueness: This compound is derived from the indole nucleus, which is a fundamental framework in many biologically active compounds. The introduction of a benzyloxy group enhances its chemical reactivity and solubility, making it suitable for various synthetic and medicinal chemistry applications.
  • Biological Relevance: Many indole derivatives are known for their diverse biological activities, including anti-inflammatory, antimicrobial, and even anticancer properties. This specific compound has gained attention for its potential influence on neuromodulation, opening up avenues for research in neuropharmacology.
  • Exciting Derivatives: The connection of the pyrrolidinyl moiety suggests possibilities for creating more complex molecules through further chemical modifications. Such derivatives could provide insights into their mechanisms of action in biological systems or lead to new therapeutic agents.
  • Research Potential: Researchers are continually exploring compounds like this one to understand their interactions at the molecular level, contributing to advancements in drug design and synthesis.
  • Quantitative Structure-Activity Relationship (QSAR): This compound could be analyzed using QSAR studies, allowing scientists to correlate its structure with biological activity. Such studies are critical in the field of medicinal chemistry for optimizing lead compounds.

Ultimately, 5-Benzyloxy-3-(1-methylpyrrolidin-2-yl)-1H-indole exemplifies the profound and intricate world of organic compounds, revealing the intricate connection between structure, function, and potential therapeutic applications. As research progresses, we anticipate uncovering even more about its implications and uses in modern science.

Synonyms
14226-68-7
5-(Benzyloxy)-3-(1-methyl-2-pyrrolidinyl)-1H-indole
3-(1-methylpyrrolidin-2-yl)-5-phenylmethoxy-1H-indole
BRN 0758312
5-Benzyloxy-3-(1-methyl-2-pyrrolidinyl)indole
INDOLE, 5-BENZYLOXY-3-(1-METHYL-2-PYRROLIDINYL)-
5-23-12-00064 (Beilstein Handbook Reference)
DTXSID10931396
5-(benzyloxy)-3-(1-methylpyrrolidin-2-yl)-1H-indole