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5-bromo-1-methyl-4-nitroimidazole

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Identification
Molecular formula
C4H4BrN3O2
CAS number
1634-50-2
IUPAC name
5-bromo-1-methyl-4-nitro-imidazole
State
State

At room temperature, 5-bromo-1-methyl-4-nitroimidazole exists as a solid. Its crystalline structure makes it stable enough to handle in powder form without significant degradation.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
207.00g/mol
Molar mass
207.0180g/mol
Density
2.1400g/cm3
Appearence

5-Bromo-1-methyl-4-nitroimidazole appears as a yellow crystalline solid. The compound tends to form well-defined crystals, making it identifiable in laboratory settings. This crystalline nature contributes to its solid-state properties and stability under standard conditions.

Comment on solubility

Solubility of 5-bromo-1-methyl-4-nitro-imidazole

The solubility of 5-bromo-1-methyl-4-nitro-imidazole in various solvents can be quite intriguing. This compound demonstrates a mix of solubility traits due to its unique structure and functional groups. Here are some key points regarding its solubility:

  • Polar Solvents: Generally, imidazole derivatives tend to exhibit greater solubility in polar solvents such as water and alcohols. This is due to the presence of nitrogen atoms which can engage in hydrogen bonding.
  • Non-Polar Solvents: Conversely, the bulky bromo and nitro groups can hinder solubility in non-polar solvents. As a result, it is less likely to dissolve effectively in oils or non-polar organic solvents.
  • pH Influence: The solubility of 5-bromo-1-methyl-4-nitro-imidazole can also be influenced by pH levels. In more acidic or alkaline environments, the ionization of the nitrogen atoms may enhance or decrease solubility.

In general, one might find that “solubility is a dance of interactions”—where the structural attributes directly dictate how well a compound will mix with various solvents. For 5-bromo-1-methyl-4-nitro-imidazole, predicting solubility in specific environments requires careful consideration of its chemical nature and the surrounding medium.

Interesting facts

Interesting Facts about 5-Bromo-1-methyl-4-nitro-imidazole

5-Bromo-1-methyl-4-nitro-imidazole is a fascinating chemical compound that belongs to the imidazole family, which is known for its diverse applications in fields such as pharmaceuticals, agriculture, and materials science.

Key Features of 5-Bromo-1-methyl-4-nitro-imidazole

  • Pharmaceutical Relevance: This compound is often studied for its potential use in various medicinal applications. The presence of the nitro group enhances its biological activity, making it of interest for drug development.
  • Versatile Building Block: As a nitro-substituted imidazole, it serves as a crucial intermediate for synthesizing a wide range of other chemical entities, including antifungal and antibacterial agents.
  • Structure and Reactivity: The bromine atom in the structure offers unique reactivity patterns, allowing for nucleophilic substitution reactions that can produce a variety of derivatives, further expanding its applications.

Environmental and Safety Considerations

Working with 5-bromo-1-methyl-4-nitro-imidazole necessitates caution due to its potential environmental impacts and toxicity. Researchers emphasize the importance of wearing appropriate protective equipment and adhering to safety protocols during handling and experimentation.

Fun Fact

Imidazole derivatives, including 5-bromo-1-methyl-4-nitro-imidazole, are widely used in the synthesis of azole antifungals, which are critical in treating various fungal infections in both human and veterinary medicine. This underscores the compound's significance in the quest for effective therapeutic agents.

Overall, 5-bromo-1-methyl-4-nitro-imidazole stands out as a remarkable compound, blending structural complexity with practical utility in scientific research and industry.

Synonyms
5-BROMO-1-METHYL-4-NITRO-1H-IMIDAZOLE
933-87-9
5-bromo-1-methyl-4-nitroimidazole
1-Methyl-5-bromo-4-nitroimidazole
Mtr 1-80
9MQV6BY151
5-bromo-4-nitro-N-methylimidazole
NSC 329116
NSC-329116
1H-Imidazole, 5-bromo-1-methyl-4-nitro-
DTXSID40239377
DTXCID60161868
868-536-5
MFCD12189404
NSC329116
1H-Imidazole,5-bromo-1-methyl-4-nitro-
UNII-9MQV6BY151
PQZGBZGIQGQAFD-UHFFFAOYSA-N
AAA93387
AKOS009542406
imidazole, 5-bromo-1-methyl-4-nitro-
AS-40881
DB-340687
CS-0038023
EN300-110363