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5-Bromo-2-chlorobenzoic acid

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Identification
Molecular formula
C7H4BrClO2
CAS number
21739-91-3
IUPAC name
5-bromo-2-chloro-benzoic acid
State
State

At room temperature, 5-bromo-2-chlorobenzoic acid is in a solid state, typically found as a crystalline powder.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
346.00
Boiling point (Kelvin)
619.15
General information
Molecular weight
251.46g/mol
Molar mass
251.4570g/mol
Density
1.8210g/cm3
Appearence

5-Bromo-2-chlorobenzoic acid appears as a white to off-white crystalline solid. It may be found in powder or crystalline form, and its exact morphology can vary based on the method of preparation.

Comment on solubility

Solubility of 5-bromo-2-chloro-benzoic acid

5-bromo-2-chloro-benzoic acid, with the chemical formula C7H4BrClO2, exhibits intriguing solubility characteristics that are influenced by its molecular structure and the presence of halogen substituents.

The solubility of this compound can be summarized as follows:

  • Solvent dependency: 5-bromo-2-chloro-benzoic acid is generally more soluble in polar solvents such as water and methanol, while it has limited solubility in non-polar solvents.
  • Influence of temperature: As with many organic acids, increased temperature tends to enhance the solubility of 5-bromo-2-chloro-benzoic acid due to increased molecular motion.
  • Ionization: In aqueous solutions, the presence of a carboxylic acid group allows for partial ionization, further increasing its solubility in water by forming anionic species.

In conclusion, the solubility of 5-bromo-2-chloro-benzoic acid is largely governed by its functional groups and the solvent conditions. Understanding these factors is essential for applications in synthesis and analysis.

Interesting facts

Interesting Facts About 5-Bromo-2-Chloro-Benzoic Acid

5-Bromo-2-chloro-benzoic acid is a fascinating compound that belongs to the category of benzoic acids, specifically halogenated benzoic acids. This compound features halogen atoms, specifically bromine and chlorine, which significantly influence its chemical properties and reactivity.

Key Characteristics:

  • Reactivity: The presence of halogens enhances the electrophilic character of the benzoic group, making it a valuable precursor in organic synthesis. Halogenated compounds often undergo substitution reactions, which are crucial in the development of pharmaceuticals and agrochemicals.
  • Applications: Research indicates that this compound is primarily utilized as an intermediate in the synthesis of various biologically active compounds. It acts as a key building block for creating complex organic molecules.
  • Biological Significance: Compounds similar to 5-bromo-2-chloro-benzoic acid have been studied for their potential *antibacterial* and *antifungal* activities, showcasing their importance in medicinal chemistry.

In the world of chemistry, halogenated acids like 5-bromo-2-chloro-benzoic acid present a unique opportunity for researchers to explore new chemical pathways and innovative applications. As Marie Curie once said, “Nothing in life is to be feared; it is only to be understood.” The understanding of such compounds can lead to breakthroughs in various scientific fields.

Research into the chemical behavior of 5-bromo-2-chloro-benzoic acid also contributes to fields such as environmental science, where understanding the persistence and degradation of halogenated compounds in the environment is crucial for assessing their safety and ecological impact.

In summary, 5-bromo-2-chloro-benzoic acid is not just a compound of interest for its own sake, but rather a window into the intricate connections between chemical synthesis, biological relevance, and environmental considerations. Its significance extends far beyond the laboratory, making it an important subject of study for current and future chemists.

Synonyms
5-Bromo-2-chlorobenzoic acid
21739-92-4
Benzoic acid, 5-bromo-2-chloro-
DTXSID40176132
EINECS 244-558-5
RefChem:533141
DTXCID6098623
244-558-5
2-Chloro-5-bromobenzoic acid
MFCD00002415
5-Bromo-2-Chloro benzoic acid
5-bromo-2-chloro-benzoic acid
MFK3MYA2FZ
Dapagliflozin Impurity 16
5-bromo-2-chorobenzoic acid
SCHEMBL18214
SCHEMBL30249448
BCP07097
SBB063089
5-Bromo-2-chlorobenzoic acid, 98%
AKOS000119557
AC-3906
CS-W012888
FB64184
PS-7656
NCGC00338868-01
SY001457
DB-023823
NS00026955
ST50308565
EN300-20497
AB01331421-02
F075288
F2191-0036
Z104478416
InChI=1/C7H4BrClO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,(H,10,11