5-Bromo-2-methyl-4-nitroimidazole | Solubility of Things

Identification

Molecular formula

C₄H₄BrN₃O₂

CAS number

IUPAC name

5-bromo-2-methyl-4-nitro-1H-imidazole

State

At room temperature, 5-bromo-2-methyl-4-nitro-1H-imidazole is in a solid state. It remains stable under normal atmospheric conditions but should be stored in a cool, dry place.

Melting point (Celsius)

238.00

Melting point (Kelvin)

511.15

Boiling point (Celsius)

345.00

Boiling point (Kelvin)

618.15

General information

Molecular weight

219.01g/mol

Molar mass

219.0070g/mol

Density

2.0030g/cm³

Appearence

5-Bromo-2-methyl-4-nitroimidazole typically appears as a pale yellow crystalline solid. The compound may have a slightly grainy texture due to the formation of microcrystals.

Comment on solubility

Solubility of 5-bromo-2-methyl-4-nitro-1H-imidazole

5-bromo-2-methyl-4-nitro-1H-imidazole, a complex heterocyclic compound, exhibits interesting solubility characteristics. Understanding its solubility can be crucial for various applications in chemistry and pharmacology.

Key Points About Solubility:

Solvent Compatibility: This compound is generally soluble in polar solvents such as water, due to the presence of the nitro group, which can engage in hydrogen bonding.
Non-polar Solvents: Solubility in non-polar organic solvents (e.g., hexane) is limited due to the polar nature of the functional groups present.
pH Dependence: The solubility may also be pH-dependent, with variations observed in acidic or basic conditions, which can affect the ionization of the compound.
Temperature Influence: Increasing the temperature typically enhances solubility for many compounds, and 5-bromo-2-methyl-4-nitro-1H-imidazole may demonstrate this trend, thus increasing its dissolving capability.

It’s important to note that "like dissolves like," thus emphasizing the significance of the solvent choice when carrying out experiments or formulations involving this compound. Depending on its solubility characteristics, it can be used effectively in various laboratories or industrial applications.

Interesting facts

Interesting Facts about 5-Bromo-2-methyl-4-nitro-1H-imidazole

5-Bromo-2-methyl-4-nitro-1H-imidazole is a fascinating compound within the class of imidazoles, which are known for their diverse biological activities and applications in various fields, including pharmaceuticals and agriculture.

Pharmaceutical Applications: This compound serves as a crucial intermediate in the synthesis of various bioactive molecules, notably in the development of antifungal and antibacterial agents. Its structural properties enhance the ability of these drugs to target specific pathogens effectively.
Biological Activity: Compounds in the imidazole family, such as 5-bromo-2-methyl-4-nitro-1H-imidazole, often display significant biological activities, including anti-inflammatory and antioxidant properties. This has generated interest in their potential use as therapeutic agents.
Research Relevance: Scientists have studied various derivatives of imidazoles for their ability to act as ligand-binding agents in medicinal chemistry, making them important molecules for drug design and development. The presence of bromine and nitro groups can alter the reactivity and interaction of these compounds with biological systems.
Environmental Importance: Some imidazole derivatives, including this compound, have shown potential in photochemical reactions. Research indicates their capability in catalyzing reactions under UV light, showcasing a possible route for environmentally friendly chemical processes.

As we navigate the intricate world of chemistry, the study of compounds like 5-bromo-2-methyl-4-nitro-1H-imidazole underlines the power of small molecular changes to influence therapeutic efficacy and environmental interactions. Each discovery can lead to significant advancements in both science and practical applications, lighting the way for future innovations in medicinal chemistry and beyond.