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5-bromo-3-isopropyl-6-methyluracil

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Identification
Molecular formula
C8H11BrN2O2
CAS number
4269-00-7
IUPAC name
5-bromo-3-isopropyl-6-methyl-1H-pyrimidine-2,4-dione
State
State

At room temperature, 5-bromo-3-isopropyl-6-methyluracil is in a solid state. Its stability as a solid is advantageous for storage and handling.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
246.09g/mol
Molar mass
246.0950g/mol
Density
1.6100g/cm3
Appearence

5-Bromo-3-isopropyl-6-methyluracil is a crystalline solid that appears as a white to off-white powder. It is typically very pure, with a consistent texture, required for research and various analytical purposes.

Comment on solubility

Solubility of 5-bromo-3-isopropyl-6-methyl-1H-pyrimidine-2,4-dione

The solubility of 5-bromo-3-isopropyl-6-methyl-1H-pyrimidine-2,4-dione is influenced by various factors, including its chemical structure and the presence of functional groups. Generally, the solubility characteristics can be summarized as follows:

  • Polarity: This compound exhibits moderate polarity due to the presence of the dione group, which can interact with polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds enhances solubility in polar solvents, making it potentially soluble in alcohols and ethers.
  • Non-polar Solvents: Given its hydrophobic isopropyl and methyl groups, it may show limited solubility in non-polar solvents, aligning more with moderate to low solubility profiles.
  • Temperature Influence: An increase in temperature often increases solubility, thus, testing solubility at various temperatures is recommended.

In conclusion, while 5-bromo-3-isopropyl-6-methyl-1H-pyrimidine-2,4-dione presents intriguing solubility characteristics, empirical testing in different solvents is crucial to determine its exact solubility profile. As the old adage goes, “The proof of the pudding is in the eating,” highlighting the importance of experimental data in confirming theoretical predictions.

Interesting facts

Interesting Facts about 5-bromo-3-isopropyl-6-methyl-1H-pyrimidine-2,4-dione

5-bromo-3-isopropyl-6-methyl-1H-pyrimidine-2,4-dione is a notable compound within the field of chemical research, particularly due to its intriguing structural and functional properties. Here are some engaging insights about this compound:

  • Diverse Applications: This compound is primarily used in pharmaceutical and agricultural chemistry. Its derivatives have been investigated for their potential as therapeutic agents, showcasing activity against various biological targets.
  • Unique Structure: The presence of both bromine and isopropyl groups makes this pyrimidine derivative a subject of interest in synthetic organic chemistry. The unique arrangement of substituents affects its reactivity and interaction with other compounds.
  • Biological Importance: Pyrimidine derivatives are known to play vital roles in biology. Molecules such as nucleotides and nucleic acids contain pyrimidine bases, showcasing the foundational importance of compounds like 5-bromo-3-isopropyl-6-methyl-1H-pyrimidine-2,4-dione in genetic information transfer and cellular processes.
  • Synthesis Challenges: The synthetic pathways to this compound involve intricate reactions, presenting challenges that can refine a chemist’s skills in organic synthesis. Mastering these techniques can aid in the development of novel pharmaceuticals.
  • Research Frontiers: Ongoing research is exploring the reactivity of similar pyrimidine derivatives, opening up possibilities for new compounds with enhanced biological activity, contributing to fields such as medicinal chemistry and drug development.

In summary, 5-bromo-3-isopropyl-6-methyl-1H-pyrimidine-2,4-dione stands as a significant player in the toolkit of organic chemists, not only for its practical applications in various scientific fields but also for the complexity and elegance of its molecular design. As noted in scientific literature, "the versatility of pyrimidine derivatives can lead to innovative solutions in modern chemistry."

Synonyms
ISOCIL
Hyvar
314-42-1
Herbicide 82
Isoprocil
5-Bromo-3-isopropyl-6-methyluracil
Isocil [ANSI]
Caswell No. 504
Du Pont herbicide 82
H-82
3-Isopropyl-5-bromo-6-methyluracil
Isocil [ANSI:ISO]
KC 1215
5-bromo-6-methyl-3-propan-2-yl-1H-pyrimidine-2,4-dione
UNII-BTE61I85CW
EINECS 206-247-2
2,4(1H,3H)-Pyrimidinedione, 5-bromo-6-methyl-3-(1-methylethyl)-
5-Brom-3-isopropyl-6-methyl-uracil
5-Bromo-3-isopropyl-6-metil-uracil
BTE61I85CW
NSC 75241
EPA Pesticide Chemical Code 011801
5-Broom-3-isopropyl-6-methyl-uracil-
BRN 0785691
Uracil, 5-bromo-3-isopropyl-6-methyl-
ISOCIL [ISO]
ISOCIL [MI]
NSC-75241
MLS002693939
DTXSID2042064
CHEBI:82230
5-Bromo-6-methyl-3-(1-methylethyl)-2,4-(1H,3H)-pyrimidinedione
5-24-07-00039 (Beilstein Handbook Reference)
5-Bromo-3-isopropyl-6-methyl, 2,4-pyrimidinedione
Isocil (ANSI)
Isocil (ANSI:ISO)
5-Bromo-6-methyl-3-(1-methylethyl)-2,4(1H,3H)-pyrimidinedione
Isoprocil [French]
2,4(1H,3H)-PYRIMIDINEDIONE, 5-BROMO-6-METHYL-3-(1-METHYLETHYL)
5-Brom-3-isopropyl-6-methyl-uracil [German]
5-Bromo-3-isopropyl-6-metil-uracil [Italian]
5-Bromo-3-isopropyl-6-methyl, 2,4-pyrimidinedione [French]
5-Broom-3-isopropyl-6-methyl-uracil- [Dutch]
NCIOpen2_004491
SCHEMBL135021
CHEMBL1901703
DTXCID0022064
HMS3094A03
NSC75241
AKOS040745875
WLN: T6MVNVJ CY1 & 1 EE F1
SMR001559878
DS-003545
NS00029099
5-Broom-3-isopropyl-6-methyl-uracil-(Dutch)
C19108
5-Bromo-3-isopropyl-6-methyl,4-pyrimidinedione
Q27155823
5-Bromo-6-methyl-3-(1-methylethyl)-2,3H)-pyrimidinedione
2,3H)-Pyrimidinedione, 5-bromo-6-methyl-3-(1-methylethyl)-
5-Bromo-3-isopropyl-6-methyl-2,4(1H,3H)-pyrimidinedione #
2,4(1H,3h)-pyrimidinedione,5-bromo-6-methyl-3-(1-methylethyl)-
206-247-2