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5-bromo-N-(4-bromophenyl)-2-hydroxybenzamide

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Identification
Molecular formula
C13H9Br2NO2
CAS number
35593-49-4
IUPAC name
5-bromo-N-(4-bromophenyl)-2-hydroxy-benzamide
State
State

At room temperature, 5-bromo-N-(4-bromophenyl)-2-hydroxybenzamide exists in a solid state.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.00
Boiling point (Celsius)
316.00
Boiling point (Kelvin)
589.00
General information
Molecular weight
373.02g/mol
Molar mass
374.0270g/mol
Density
1.7560g/cm3
Appearence

The compound 5-bromo-N-(4-bromophenyl)-2-hydroxybenzamide appears as a crystalline solid, typically white or off-white in color. It's known for its slightly powdery texture.

Comment on solubility

Solubility of 5-bromo-N-(4-bromophenyl)-2-hydroxy-benzamide

Understanding the solubility of 5-bromo-N-(4-bromophenyl)-2-hydroxy-benzamide is crucial for its application in various chemical processes and pharmaceutical formulations. This compound, with its intricate molecular structure, exhibits specific solubility characteristics:

  • Polarity: The presence of hydroxyl (-OH) groups enhances polarity, suggesting increased solubility in polar solvents, such as water.
  • Halogen Substituents: The Br atoms contribute to both sterics and electronic effects, impacting solubility in organic solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the hydroxyl group can further improve solubility in dipolar aprotic solvents.

In an experimental context, it is noted that:

  • The compound is likely to be partially soluble in water but more soluble in organic solvents like ethanol or DMSO.
  • Factors like temperature and pH can also influence solubility, making it advisable to conduct empirical studies to determine precise solubility limits.
  • Interactions with other solutes should be considered, as they may lead to complex formations that alter solubility profiles.

In summary, while 5-bromo-N-(4-bromophenyl)-2-hydroxy-benzamide's solubility is influenced by various structural factors, further analysis and experimentation are key to fully understanding its behavior in different solvent systems.

Interesting facts

Interesting Facts About 5-Bromo-N-(4-bromophenyl)-2-hydroxy-benzamide

5-Bromo-N-(4-bromophenyl)-2-hydroxy-benzamide is a fascinating compound with notable chemical and biological properties. Here are some engaging details:

  • Structure and Reactivity: The compound features multiple bromine atoms, which can significantly influence its reactivity and stability. Bromine atoms often increase the polarity of a molecule, enhancing its potential interactions with biological systems.
  • Hydroxyl Group: The presence of a hydroxyl group (–OH) in its structure contributes to its solubility in polar solvents and plays a crucial role in its biological activities. Hydroxyl groups are known to participate in hydrogen bonding, which can affect the compound’s interaction with cellular targets.
  • Pharmaceutical Relevance: Compounds like this one are often investigated for their potential pharmaceutical applications. They can serve as intermediates in the synthesis of more complex drug molecules, and the bromophenyl and hydroxyl groups may provide important pharmacological properties.
  • Research and Studies: The unique structure of this compound has made it a subject of interest in various research fields, including medicinal chemistry and materials science. Different studies explore its potential as an anti-cancer agent or its applications in organic synthesis.
  • Toxicology Considerations: While studying such brominated compounds, it is also important to analyze their environmental impact and biological safety. The brominated aromatic compounds can exhibit toxicity to aquatic life, which raises concerns about their ecological footprint.

In summary, the intriguing properties of 5-bromo-N-(4-bromophenyl)-2-hydroxy-benzamide make it a subject of significant interest in both academic and industrial contexts. As researchers continue to explore its uses, we can anticipate discovering more about its intriguing capabilities and potential applications.

Synonyms
DIBROMSALAN
87-12-7
4',5-Dibromosalicylanilide
Dibromsalen
Disanyl
Bromsalicylanilide
Bromosalicylanilide
DIBASK
Dibromsalanum
Dibronsalan
NSC-20527
Caswell No. 287C
5-Bromosalicyl-4-bromoanilide
Dibromsalan [USAN:INN]
Dibromsalanum [INN-Latin]
Dibronsalan [INN-Spanish]
5-Bromosalicylic acid p-bromoanilide
3-Bromo-6-hydroxybenz-p-bromanilide
Salicylanilide, 4',5-dibromo-
BENZAMIDE, 5-BROMO-N-(4-BROMOPHENYL)-2-HYDROXY-
EINECS 201-724-1
NSC 20527
EPA Pesticide Chemical Code 077402
BRN 1125597
Dibromsalan (USAN)
N9900K2RBT
WR 52606
p-Bromanilid kyseliny 5-bromsalicylove [Czech]
DIBROMSALAN [INN]
DIBROMSALAN [USAN]
p-Bromanilid kyseliny 5-bromsalicylove
DIBROMSALAN [MART.]
DIBROMSALAN [WHO-DD]
DTXSID1041500
Dibromsalanum (INN-Latin)
Dibronsalan (INN-Spanish)
DIBROMSALAN (MART.)
DTXCID9021500
201-724-1
Temasept
5-bromo-N-(4-bromophenyl)-2-hydroxybenzamide
5-bromo-N-(4-bromophenyl)-2-hydroxy-benzamide
NSC20527
component of Diaphene
component of ASC-4
component of Temasept I
Salicylanilide,5-dibromo-
WLN: QR DE BVMR DE
UNII-N9900K2RBT
CHEMBL21869
SCHEMBL646973
CTFFKFYWSOSIAA-UHFFFAOYSA-N
NSC81947
NSC-81947
NS00039169
D03780
H37705
Q27284731
Z68085475