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5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole

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Identification
Molecular formula
C10H7BrClNO
CAS number
183208-36-8
IUPAC name
5-(bromomethyl)-3-(4-chlorophenyl)isoxazole
State
State

At room temperature, it is generally in solid form as a crystalline powder.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.00
Boiling point (Celsius)
289.00
Boiling point (Kelvin)
562.00
General information
Molecular weight
273.52g/mol
Molar mass
273.5150g/mol
Density
1.6800g/cm3
Appearence

The compound appears as a pale yellow crystalline powder. Its crystallinity can vary depending on the method of synthesis and purity.

Comment on solubility

Solubility of 5-(bromomethyl)-3-(4-chlorophenyl)isoxazole

The solubility of 5-(bromomethyl)-3-(4-chlorophenyl)isoxazole is influenced by several factors, primarily its molecular structure and polarity. This compound features both bromomethyl and chlorophenyl groups, which can impact its interactions with solvents.

Considering the properties of this isoxazole derivative:

  • Polarity: The presence of halogen atoms (bromine and chlorine) typically increases the polarity of organic compounds, which may enhance solubility in polar solvents.
  • Hydrophobic Regions: However, the hydrophobic nature of the aromatic ring may limit solubility in very polar solvents.
  • Solvent Compatibility: This compound is likely to be more soluble in organic solvents such as dichloromethane or ethanol rather than in water.

In general, compounds like 5-(bromomethyl)-3-(4-chlorophenyl)isoxazole often exhibit variable solubility depending on conditions such as temperature and the presence of other solutes. Therefore, it is crucial to evaluate solubility through experimental methods to ascertain specific solvent interaction.

In summary, while this compound exhibits some potential for solubility in organic media, its actual dissolving behavior can be complex; researchers should always conduct empirical tests to determine precise solubility data.

Interesting facts

Interesting Facts about 5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole

5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole is a fascinating compound that showcases the versatile nature of isoxazole derivatives in organic chemistry. Here are some insightful points about this unique compound:

  • Structural Diversity: Isoxazoles are known for their diverse structural variations. The presence of a bromomethyl group and a chlorophenyl moiety lends this compound its distinctive chemical reactivity and properties.
  • Biological Significance: Compounds like 5-(bromomethyl)-3-(4-chlorophenyl)isoxazole are often studied for their potential *pharmacological activities*. Isoxazole derivatives have been explored for applications in medicine and agriculture.
  • Synthetic Relevance: The synthesis of this compound often involves *multistep reactions*, which challenge chemists to think creatively about reaction conditions and mechanisms. The unique synthesis pathways can lead to breakthrough drugs and agrochemicals.
  • Research Potential: The combination of different functional groups in this compound opens avenues for further *research into reactivity*. Understanding how modifications impact the behavior of isoxazoles aids in developing new materials and pharmaceuticals.

Overall, 5-(bromomethyl)-3-(4-chlorophenyl)isoxazole is more than just a chemical entity; it is a gateway to exploring innovative compounds with real-world applications. As researchers delve deeper into its properties and behaviors, we may uncover even more exciting uses for this intriguing molecule.

Synonyms
5300-92-5
BRN 1212727
5-Bromomethyl-3-(p-chlorophenyl)isoxazole
ISOXAZOLE, 5-BROMOMETHYL-3-(p-CHLOROPHENYL)-
DTXSID20201052
DTXCID20123543
5-(bromomethyl)-3-(4-chlorophenyl)isoxazole
5-(bromomethyl)-3-(4-chlorophenyl)-1,2-oxazole
MFCD06738491
SCHEMBL3688842
YGCXXYLQISERCR-UHFFFAOYSA-N
FAA30092
AKOS009096509
AB27225
5-bromomethyl-3-(4-chlorophenyl)isoxazole
DB-071620
EN300-24531
5-(bromomethyl)-3-(4-chlorophenyl)-isoxazole
G27680
Z198974074
5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole, AldrichCPR