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Barbital

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Identification
Molecular formula
C8H12N2O3
CAS number
57-44-3
IUPAC name
5-butyl-1-phenyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, barbital is in a solid state. It is usually stable under normal conditions and does not react with most substances. However, as a solid, it must be handled carefully to avoid dispersion of powder in the laboratory environment.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
206.25g/mol
Molar mass
206.2450g/mol
Density
1.1520g/cm3
Appearence

Barbital typically appears as a white crystalline powder. It is odorless and has a slightly bitter taste. The compound is often used in laboratory settings and may be provided in a powdered form for ease of measurement and application.

Comment on solubility

Solubility of 5-butyl-1-phenyl-hexahydropyrimidine-2,4,6-trione

The solubility of 5-butyl-1-phenyl-hexahydropyrimidine-2,4,6-trione can be quite intriguing due to its unique structure. Solubility is influenced by several factors, including:

  • Polarity: The compound contains both non-polar (butyl and phenyl groups) and polar functional groups (the trione), which can lead to varied solubility in different solvents.
  • Hydrogen Bonding: The presence of the ketone groups can facilitate hydrogen bonding with potential solvents, enhancing solubility in polar solvents like water or alcohols.
  • Hydrophobic Interactions: The butyl and phenyl groups might promote solubility in non-polar solvents such as hexane or toluene.

In practical terms, one might expect:

  1. The compound to exhibit moderate to low solubility in water, primarily due to its larger hydrophobic regions.
  2. Enhanced solubility in organic solvents, where the hydrophobic interactions can dominate.

As a general rule, it can be stated that "like dissolves like," meaning the solubility of this compound will likely be greater in solvents that share similar chemical properties. Ultimately, the precise solubility can be experimentally determined, but understanding these factors provides valuable insight into the behavior of 5-butyl-1-phenyl-hexahydropyrimidine-2,4,6-trione in different environments.

Interesting facts

Interesting Facts about 5-butyl-1-phenyl-hexahydropyrimidine-2,4,6-trione

5-butyl-1-phenyl-hexahydropyrimidine-2,4,6-trione is a fascinating compound that showcases the intricate world of organic chemistry. This compound belongs to the pyrimidine family, which is known for its diverse roles in biochemistry and pharmaceuticals.

Key Points to Consider:

  • Structural Diversity: The compound is a derivative of hexahydropyrimidine, an important class of nitrogen-containing heterocycles.
  • Functional Importance: The trione functionality (3 carbonyl groups) plays a crucial role in determining the reactivity and biological properties of the compound.
  • Biological Relevance: Pyrimidine derivatives like this one often exhibit a variety of biological activities, making them relevant in drug design and medicinal chemistry.
  • Versatile Applications: Compounds similar to 5-butyl-1-phenyl-hexahydropyrimidine-2,4,6-trione may be investigated for their potential applications in anti-cancer therapy, antimicrobial agents, and enzyme inhibitors.

This compound’s unique structure provides a great opportunity for students and chemists to explore various reactions and applications. As seen in organic synthesis, the ability to manipulate carbonyl groups and introduce substituents can lead to the development of new compounds with tailor-made properties.
Moreover, researchers are continually studying how the variations in substituents, such as the butyl and phenyl groups in this compound, can influence its pharmacological profiles.

In summary, 5-butyl-1-phenyl-hexahydropyrimidine-2,4,6-trione is not just a name; it represents a gateway to numerous research avenues and potential therapeutic applications that are both exciting and impactful in the scientific community.

Synonyms
5-Butyl-1-phenylbarbituric acid
18160-14-0
5-butyl-1-phenyl-1,3-diazinane-2,4,6-trione
BARBITURIC ACID, 5-BUTYL-1-PHENYL-
NSC 85041
BRN 0250782
NSC85041
5-Butyl-1-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-butyl-1-phenyl-
NCIOpen2_004969
WLN: T6VMVNV FHJ DR& F4
NSC-85041
5-Butyl-1-phenyl-2,6(1H,3H,5H)-pyrimidinetrione
2,6(1H,3H,5H)-Pyrimidinetrione, 5-butyl-1-phenyl-