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5-chloro-2-mercaptobenzothiazole

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Identification
Molecular formula
C7H4ClNOS2
CAS number
615-22-5
IUPAC name
5-chloro-1,3-benzothiazole-2-thiol
State
State

At room temperature, 5-chloro-2-mercaptobenzothiazole is in a solid state.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.00
Boiling point (Celsius)
298.00
Boiling point (Kelvin)
571.00
General information
Molecular weight
187.66g/mol
Molar mass
187.6600g/mol
Density
1.5170g/cm3
Appearence

5-Chloro-2-mercaptobenzothiazole appears as a pale yellow crystalline powder. It is known for its distinct characteristic odor, which may be unpleasant or irritating. The solid is fine and may form lumps under certain conditions due to its powdery texture.

Comment on solubility

Solubility of 5-chloro-1,3-benzothiazole-2-thiol

The solubility of 5-chloro-1,3-benzothiazole-2-thiol can be influenced by several factors, making it a subject of interest in both academia and industry. This compound demonstrates a unique profile in various solvents:

  • Solvent Nature: Polar solvents such as water may exhibit limited solubility due to the hydrophobic characteristics of the benzothiazole ring.
  • Hydrogen Bonding: The presence of the thiol group (–SH) can participate in hydrogen bonding, which may enhance solubility in polar organic solvents.
  • pH Dependency: The solubility of thiol compounds can vary significantly with pH, as protonation can affect their overall charge and solubility.
  • Temperature Effects: Typically, an increase in temperature may improve the solubility of many solids, including 5-chloro-1,3-benzothiazole-2-thiol, due to increased kinetic energy.

To summarize, while 5-chloro-1,3-benzothiazole-2-thiol may not be highly soluble in all solvents, its solubility is enhanced in specific conditions, reflecting the compound's unique chemical properties. Understanding these solubility dynamics is crucial for its applications and handling in chemical processes.

Interesting facts

Interesting Facts about 5-Chloro-1,3-benzothiazole-2-thiol

5-Chloro-1,3-benzothiazole-2-thiol is a fascinating compound that belongs to the class of benzothiazole derivatives, which are known for their diverse range of applications in various fields. Here are some intriguing insights:

  • Biological Activity: This compound exhibits significant biological properties, making it of great interest in medicinal chemistry. It has been studied for its potential as an antimicrobial agent, showcasing efficacy against several pathogens.
  • Colorimetric Detection: 5-Chloro-1,3-benzothiazole-2-thiol can be used in analytical chemistry as a reagent for the detection of heavy metals. Its ability to form coordination complexes can be utilized in colorimetric assays, aiding in environmental monitoring.
  • Industrial Applications: The applications of this compound extend beyond laboratory settings. It is often employed in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, due to its functional group reactivity.
  • Structure-Activity Relationship Studies: Researchers focus on the study of its structure-activity relationships, which can provide important insights for developing new compounds with improved therapeutic characteristics.

In conclusion, 5-chloro-1,3-benzothiazole-2-thiol exemplifies the intersection of chemistry and biology, underscoring the importance of interdisciplinary research in discovering new materials with valuable properties. As noted by chemical researchers, “The exploration of small molecules often leads to large breakthroughs in science.” This compound serves as a testament to that principle.