5-Chloro-2-(2-(piperidin-1-yl)ethylthio)-1,3-benzoxazole

Identification

Molecular formula

C₁₄H₁₅ClN₂OS

CAS number

146676-03-9

IUPAC name

5-chloro-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

State

At room temperature, the compound exists as a crystalline solid.

Melting point (Celsius)

102.00

Melting point (Kelvin)

375.15

Boiling point (Celsius)

470.00

Boiling point (Kelvin)

743.15

General information

Molecular weight

284.80g/mol

Molar mass

284.7980g/mol

Density

1.3000g/cm³

Appearence

The compound typically appears as an off-white to light yellow crystalline solid.

Comment on solubility

Solubility of 5-chloro-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

The solubility of 5-chloro-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole in different solvents can vary significantly due to its complex molecular structure. Here are some key points to consider regarding its solubility:

Polar solvents: This compound is likely to demonstrate better solubility in polar solvents, such as water and methanol, due to potential hydrogen bonding and dipole-dipole interactions.
Nonpolar solvents: Conversely, in nonpolar solvents like hexane or benzene, the solubility may be quite limited. The presence of the benzoxazole ring enhances lipophilicity, but the overall balance of functional groups plays a crucial role.
Temperature effects: Temperature can significantly influence solubility. As temperature increases, solubility tends to increase for most solids; however, this can vary based on specific interactions within the compound.
pH impact: The solubility may also be affected by the pH of the solution, especially if the compound has acidic or basic functional groups that can ionize.

In summary, the solubility of 5-chloro-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole is a multifaceted topic that requires consideration of solvent polarity, temperature, and pH. Such factors ultimately determine the bioavailability and usefulness of the compound in various chemical and pharmaceutical applications. As quoted in solubility studies, "The right solvent can make all the difference."

Interesting facts

Interesting Facts about 5-Chloro-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

5-Chloro-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole is a fascinating compound due to its structural complexity and biological significance. Here are some key points that make it remarkable:

Pharmacological Importance: This compound belongs to a class of substances known as benzoxazoles, which are recognized for their diverse biological activities. Research indicates that they may exhibit potential as antimicrobial, anti-inflammatory, and anticancer agents.
Unique Structure: The presence of a chloro group and a piperidine ring contributes to its unique chemical reactivity and interactions, making it a subject of interest in medicinal chemistry.
Synthesis routes: The synthesis of compounds with similar structures often involves complex organic reactions such as nucleophilic substitutions and functional group manipulations, making the study of its synthesis a valuable exercise in advanced organic chemistry.
Research Applications: Scholars are increasingly investigating the effects of this compound on different biological systems, including its role in neuropharmacology. The presence of the piperidine moiety suggests potential interactions with neurotransmitter systems.

As a member of a growing family of compounds with therapeutic potential, 5-chloro-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole exemplifies the ongoing innovation in drug discovery and development. The exploration of its properties could lead to novel treatments for various diseases.

“The beauty of chemistry lies in its constant evolution; with each synthesis, we forge new pathways to understanding and healing.”