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Chloroquine

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Identification
Molecular formula
C18H26ClN3O
CAS number
50-63-5
IUPAC name
5-chloro-2-[2-(diethylamino)ethoxy]benzamide
State
State
At room temperature, chloroquine is typically in a solid state, specifically as a crystalline powder.
Melting point (Celsius)
87.00
Melting point (Kelvin)
360.15
Boiling point (Celsius)
422.00
Boiling point (Kelvin)
695.15
General information
Molecular weight
319.87g/mol
Molar mass
319.8720g/mol
Density
1.1573g/cm3
Appearence

Chloroquine typically appears as a white to slightly yellow crystalline powder.

Comment on solubility

Solubility of 5-chloro-2-[2-(diethylamino)ethoxy]benzamide

The solubility of 5-chloro-2-[2-(diethylamino)ethoxy]benzamide in various solvents can exhibit distinct behaviors due to its unique structure. Understanding its solubility is crucial for its application in pharmacology and chemical synthesis. Here are some noteworthy points:

  • Polar Solvents: This compound is likely to have moderate solubility in polar solvents such as water, due to the presence of the diethylamino group that can engage in hydrogen bonding.
  • Non-Polar Solvents: Conversely, it may show greater solubility in non-polar solvents owing to its aromatic system and alkyl chains, which favor hydrophobic interactions.
  • Temperature Dependency: The solubility can also be influenced by temperature; typically, an increase in temperature may enhance solubility in both polar and non-polar solvents.
  • Data Variation: It's important to note that experimental data can vary significantly based on purity and the specific conditions used during testing.

In summary, the solubility profile of 5-chloro-2-[2-(diethylamino)ethoxy]benzamide is complex and dependent on the solvent type, temperature, and experimental parameters. For accurate predictions and applications, detailed solubility studies in different solvents are essential.

Interesting facts

Interesting Facts about 5-Chloro-2-[2-(diethylamino)ethoxy]benzamide

5-Chloro-2-[2-(diethylamino)ethoxy]benzamide is a remarkable compound with intriguing properties and a significant role in the field of medicinal chemistry. Here are some noteworthy aspects of this compound:

  • Pharmacological Relevance: This compound is known for its potential applications in pharmacology, particularly as a drug candidate. It exhibits properties that may aid in treating various conditions, such as anxiety and depression.
  • Research Significance: Scientists are fascinated by this compound due to its dual function. The presence of both a chloro group and a diethylamino moiety enhances its interaction with biological systems, making it a target of ongoing research.
  • Structure-Activity Relationship (SAR): The unique structure of 5-Chloro-2-[2-(diethylamino)ethoxy]benzamide allows researchers to explore how modifications to its chemical structure can affect its biological activity. This research is crucial for drug design and optimization.
  • Versatile Synthesis: The compound can be synthesized through various methods, providing a platform for chemists to develop new derivatives with enhanced efficacy, safety, or selectivity.
  • Future Prospects: Ongoing studies aim to unveil more about the compound’s mechanism of action, which could lead to novel therapeutic applications. Its potential use as a template for developing new medications makes it an exciting subject in drug discovery.

In summary, 5-chloro-2-[2-(diethylamino)ethoxy]benzamide is not just another chemical compound; it holds substantial promise in advancing medicinal chemistry and boosting the understanding of how certain compounds can mediate biological effects. As researchers continue to investigate this compound, we may witness exciting developments that could impact various therapeutic areas.

Synonyms
5-Chloro-2-(2-(diethylamino)ethoxy)benzamide
Sch 1301
BRN 2696967
BENZAMIDE, 5-CHLORO-2-(2-(DIETHYLAMINO)ETHOXY)-
Amide dell'acido-2-dietilaminoetilossi-5-clorobenzoico [Italian]
DTXSID90198960
Amide dell'acido-2-dietilaminoetilossi-5-clorobenzoico
DTXCID50121451
669-237-0
5092-73-9
5-chloro-2-(2-diethylaminoethyloxy)benzamide
CCB29151
AKOS024321060