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Deferiprone

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Identification
Molecular formula
C6H6ClNO2
CAS number
30652-11-0
IUPAC name
5-chloro-2-hydroxy-1H-pyridin-4-one
State
State
Solid at room temperature. This compound is typically stable under standard conditions, and its solid form is utilized in pharmaceutical formulations.
Melting point (Celsius)
272.50
Melting point (Kelvin)
545.50
Boiling point (Celsius)
536.00
Boiling point (Kelvin)
809.00
General information
Molecular weight
157.57g/mol
Molar mass
157.5500g/mol
Density
1.4300g/cm3
Appearence

Deferiprone appears as a white to off-white crystalline powder. The compound is known for its applications in chelation therapy, specifically for the treatment of iron overload conditions.

Comment on solubility

Solubility of 5-chloro-2-hydroxy-1H-pyridin-4-one

The solubility of 5-chloro-2-hydroxy-1H-pyridin-4-one, with the chemical formula C6H6ClNO2, is an intriguing topic due to its polar functional groups. Understanding its solubility behavior can provide valuable insights into its potential applications in various fields. Here are some key points regarding its solubility:

  • Polar Characteristics: The presence of the hydroxyl group (-OH) in the compound enhances its ability to engage in hydrogen bonding, which generally increases solubility in polar solvents like water.
  • Chlorine Influence: The chlorine substituent can affect the overall polarity of the molecule, potentially making it soluble in a range of organic solvents as well.
  • Common Solvents: This compound is likely soluble in:
    • Water
    • Ethanol
    • Dimethyl sulfoxide (DMSO)
  • Temperature Dependency: Solubility often increases with temperature, which can be a key factor in practical applications.
  • Industrial Relevance: Its solubility profile suggests it may be used in formulations that require specific solvate interactions.

In conclusion, the solubility of 5-chloro-2-hydroxy-1H-pyridin-4-one reflects a balance of polar and nonpolar characteristics, making it an interesting compound to study in terms of its interactions in various media.

Interesting facts

Interesting Facts about 5-Chloro-2-Hydroxy-1H-Pyridin-4-One

5-Chloro-2-hydroxy-1H-pyridin-4-one is a fascinating compound that plays a significant role in medicinal chemistry, especially in the development of pharmaceutical agents. This compound is particularly known for its biological activities and has been studied for its potential in treating various diseases.

Key Features

  • Pharmacological Interest: It has been investigated for its anti-inflammatory and anti-cancer properties. The presence of the chloro and hydroxy groups contributes to its activity, making it a valuable template in drug discovery.
  • As a Chelating Agent: Due to the hydroxyl and nitrogen groups, it can act as a chelating agent, binding to metal ions which can enhance stability and bioavailability in pharmaceutical formulations.
  • Research Applications: This compound serves as a model in studying pyridinic derivatives, further expanding its utility in chemical and biological research.
  • Synthetic Versatility: 5-Chloro-2-hydroxy-1H-pyridin-4-one can be synthesized through various organic reactions, showcasing its accessibility for laboratory studies and applications.

As noted by chemists, "The pyridinone scaffold offers a unique platform for the development of innovative therapeutic agents." This underscores the importance of compounds like 5-chloro-2-hydroxy-1H-pyridin-4-one in the ongoing search for effective treatments in modern medicine.

Overall, 5-chloro-2-hydroxy-1H-pyridin-4-one stands out not just for its chemical structure but also for the numerous possibilities it offers in the realms of medicinal chemistry and pharmacology.