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5-Chlorosalicylaldehyde

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Identification
Molecular formula
C7H5ClO2
CAS number
6393-45-1
IUPAC name
5-chloro-2-hydroxy-benzaldehyde
State
State

The compound is typically a solid at room temperature under standard conditions.

Melting point (Celsius)
72.00
Melting point (Kelvin)
345.15
Boiling point (Celsius)
253.00
Boiling point (Kelvin)
526.15
General information
Molecular weight
156.57g/mol
Molar mass
156.5600g/mol
Density
1.4190g/cm3
Appearence

5-Chlorosalicylaldehyde appears as a light yellow solid at room temperature.

Comment on solubility

Solubility of 5-Chloro-2-hydroxy-benzaldehyde

5-Chloro-2-hydroxy-benzaldehyde, with its molecular structure featuring a hydroxyl group and a chlorinated aromatic ring, exhibits soluble characteristics that are influenced by its functional groups. The solubility of this compound can be highlighted as follows:

  • Solvent Dependence: It is soluble in polar solvents such as water and alcohols due to its ability to form hydrogen bonds.
  • Hydroxyl Group Impact: The presence of the -OH group enhances its compatibility with polar solvents, increasing solubility.
  • Limited Non-polar Solubility: Conversely, in non-polar solvents, solubility is significantly reduced, as the aromatic ring does not interact favorably with non-polar environments.

In summary, the solubility of 5-chloro-2-hydroxy-benzaldehyde is primarily governed by its polar functional groups, which promote significant solubility in polar media compared to non-polar solvents. Understanding these solubility characteristics is critical for effective applications in various chemical processes and formulations.

Interesting facts

Interesting Facts about 5-Chloro-2-hydroxy-benzaldehyde

5-Chloro-2-hydroxy-benzaldehyde, also known as 2-hydroxy-5-chlorobenzaldehyde, is a fascinating aromatic compound with a variety of applications in both chemical synthesis and industrial processes. Here are some interesting aspects to note:

  • Functional Groups: This compound contains both an aldehyde group and a phenolic hydroxyl group. The presence of these functional groups makes it an important intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals.
  • Biological Activity: Research has shown that 5-chloro-2-hydroxy-benzaldehyde can exhibit antimicrobial and antifungal properties. Such attributes make it of interest in the development of new medicinal agents.
  • Versatility in Synthesis: This compound serves as a precursor for various derivatives that can be tailored for specific purposes, including dyes, fragrances, and other specialty chemicals.
  • Environmental Considerations: As with many chlorinated compounds, the environmental impact should be assessed carefully. While it has beneficial applications, understanding the path of its degradation in the environment is crucial for sustainable use.
  • Cultural Relevance: In some cultures, compounds related to aromatic aldehydes are used in traditional remedies, emphasizing the intersection of chemistry and cultural practices.

This compound exemplifies the importance of aromatic chemistry and its profound implications in multiple fields ranging from medicine to environmental science. As the quote goes, "The best way to predict the future is to invent it." By continuing to explore compounds like 5-chloro-2-hydroxy-benzaldehyde, chemists are inventing pathways to new discoveries and innovations.

Synonyms
5-Chlorosalicylaldehyde
5-Chloro-2-hydroxybenzaldehyde
2-Hydroxy-5-chlorobenzaldehyde
Benzaldehyde, 5-chloro-2-hydroxy-
4-Chloro-2-formylphenol
SALICYLALDEHYDE, 5-CHLORO-
UNII-4GCC8ZKM3O
4GCC8ZKM3O
NSC 3811
EINECS 211-244-4
3-chloro-6-hydroxybenzaldehyde
BRN 0636632
5-chloro-2-hydroxy benzaldehyde
AI3-52302
NSC-3811
DTXSID7022099
4-08-00-00224 (Beilstein Handbook Reference)
DTXCID502099
211-244-4
fugkcsrlaqkuhg-uhfffaoysa-n
inchi=1/c7h5clo2/c8-6-1-2-7(10)5(3-6)4-9/h1-4,10
635-93-8
5-chloro-2-hydroxy-benzaldehyde
MFCD00003331
5-Chlorosalicyaldehyde
5-chloro salicylaldehyde
5-chloro-salicylaldehyde
5-Chloro2-Hydroxybenzaldehyde
SCHEMBL247839
5-Chlorosalicylaldehyde, 98%
2-hydroxy-5-chloro-benzaldehyde
5-chloro,2-hydroxy benzaldehyde
CHEMBL3660361
NSC3811
BDBM111028
benzaldehyde, 3-chloro-6-hydroxy-
STR01596
AC7515
STK199255
AKOS000112410
AB00314
AC-2944
CS-W007438
FC11035
PS-3485
NCGC00340461-01
BP-13319
SY003396
DB-013447
NS00035503
EN300-18277
AB01333427-02
A1-00321
US8614253, .3-59
Q27259564
Z57772439
F2191-0153