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5-chlorosalicylic acid

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Identification
Molecular formula
C7H5ClO3
CAS number
321-14-2
IUPAC name
5-chloro-2-hydroxy-benzoic acid
State
State

At room temperature, 5-chlorosalicylic acid is typically found in a solid state. It retains a crystalline structure and is not prone to rapid evaporation or volatility.

Melting point (Celsius)
232.00
Melting point (Kelvin)
505.15
Boiling point (Celsius)
317.00
Boiling point (Kelvin)
590.15
General information
Molecular weight
172.57g/mol
Molar mass
172.5700g/mol
Density
1.6450g/cm3
Appearence

5-Chlorosalicylic acid appears as a white to off-white crystalline powder. It is known for being relatively stable under normal conditions, but like many salicylic acid derivatives, care should be taken to protect it from excessive moisture and light to prevent degradation.

Comment on solubility

Solubility Overview of 5-chloro-2-hydroxy-benzoic acid

5-chloro-2-hydroxy-benzoic acid, also known as Chlorosalicylic acid, exhibits interesting solubility characteristics that are essential for its applications in various fields. Understanding its solubility can provide insights into its behavior in different environments.

Solubility Characteristics:

  • Solvent Dependency: This compound is generally soluble in polar solvents such as water, alcohols, and ethers.
  • Temperature Influence: Increased temperature often enhances solubility; hence, solubility can vary with temperature fluctuations.
  • pH Sensitivity: The presence of acidic or basic conditions may impact its solubility, making it more soluble in basic solutions due to deprotonation.

To summarize, 5-chloro-2-hydroxy-benzoic acid displays a notable solubility profile that is influenced by:

  • Polarity of the solvent
  • Temperature
  • pH of the solution

These factors play a crucial role in how this compound interacts in practical applications, emphasizing the importance of solubility in chemical processes.

Interesting facts

Interesting Facts about 5-Chloro-2-Hydroxybenzoic Acid

5-Chloro-2-hydroxybenzoic acid, commonly known as Chlorosalicylic acid, is a fascinating compound with various applications in both industrial and biomedical fields. Here are some intriguing points about this compound:

  • Structure and Function: This compound is characterized by a benzene ring substituted with both a chlorine atom and a hydroxyl group, in addition to the carboxylic acid functional group. This unique structure contributes to its biological activity and potential therapeutic uses.
  • Antimicrobial Properties: Research has shown that 5-Chloro-2-hydroxybenzoic acid exhibits antimicrobial properties, making it a useful agent in the development of antibacterial agents and preservatives.
  • Biochemistry Applications: Due to its structural similarity with salicylic acid, it can serve as a valuable tool in metabolic studies. As a part of various biochemical pathways, it is often explored in research related to plant hormones and signaling.
  • Natural Sources: Interestingly, chlorosalicylic acid can be found in nature, and certain plants produce this compound as a response to stress or injury, showcasing how plants adapt and defend themselves chemically.
  • Potential Therapeutic Uses: The potential applications extend to the development of pharmaceuticals due to its biochemical activity, particularly in anti-inflammatory and analgesic properties, similar to its cousin, salicylic acid.

As chemists and researchers continue to explore this compound, it opens up avenues for innovative uses in medicine, agriculture, and materials science. The multifunctional nature of 5-chloro-2-hydroxybenzoic acid ensures that it remains a compound of interest across various scientific disciplines.

Synonyms
5-CHLOROSALICYLIC ACID
5-Chloro-2-hydroxybenzoic acid
321-14-2
Benzoic acid, 5-chloro-2-hydroxy-
2-Hydroxy-5-chlorobenzoic acid
5 CSA
Salicylic acid, 5-chloro-
CCRIS 4485
5-chloro salicylic acid
5-Chloro-2-hydroxy-benzoic acid
UNII-J2YFG68VCZ
J2YFG68VCZ
EINECS 206-283-9
MFCD00002457
NSC 30111
BRN 2046665
AI3-22259
CHEBI:420128
NSC-30111
CHEMBL1375
DTXSID7059806
4-10-00-00207 (Beilstein Handbook Reference)
5-chloro-2-hydroxobenzoic acid
5-Chloro-2-hydroxybenzoicacid
5-Chloro-2-hydroxybenzoic Acid; NSC 30111; 2-Hydroxy-5-chlorobenzoic Acid;
5-chloro-salicylic acid
5-chloro-salicyclic acid
5-ChlorsalicylsA currencyure
Oprea1_451559
SCHEMBL130605
5-Chlorosalicylic acid, 98%
2-hydroxy 5-chlorobenzoic acid
DTXCID1038452
5-chloro-2-hydroxy benzoic acid
NSC30111
BDBM50240969
STL163471
AKOS000120502
CS-W017582
FC38942
FS-3270
HY-W016866
AC-10403
PD182541
NS00009907
EN300-21514
5-chlorosalicylic acid kosher & halal certified
5-Chlorosalicylic acidKosher & Halal certified
Q27225743
F0211-0006
Z104500560
206-283-9