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5-Chloro-2-methylbenzothiazole

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Identification
Molecular formula
C8H6ClNS
CAS number
39156-41-7
IUPAC name
5-chloro-2-methyl-1,3-benzothiazole
State
State

5-Chloro-2-methylbenzothiazole is typically encountered as a solid at room temperature, such as a crystalline powder, although its precise state can depend on its purity and specific conditions like temperature and pressure.

Melting point (Celsius)
27.00
Melting point (Kelvin)
300.15
Boiling point (Celsius)
267.40
Boiling point (Kelvin)
540.60
General information
Molecular weight
183.65g/mol
Molar mass
183.6420g/mol
Density
1.3500g/cm3
Appearence

5-Chloro-2-methylbenzothiazole appears as a colorless to light yellow crystalline solid. It may also be encountered as a powder or in crystalline form. When in solid state, it can reflect light, giving it a slight sheen.

Comment on solubility

Solubility of 5-chloro-2-methyl-1,3-benzothiazole

5-chloro-2-methyl-1,3-benzothiazole is an interesting compound when it comes to solubility behavior. As a member of the benzothiazole family, its solubility is significantly influenced by its structural features. Here are some key points to consider:

  • Polar and Nonpolar Character: The presence of the chlorine and methyl groups affects its polarity, leading to moderate solubility in organic solvents.
  • Solvent Interaction: It tends to dissolve well in organic solvents such as ethanol and acetone, but shows limited solubility in water due to its hydrophobic characteristics.
  • Temperature Dependency: Like many organic compounds, solubility may increase with temperature, suggesting that warmer solvents could enhance dissolution.

In summary, while 5-chloro-2-methyl-1,3-benzothiazole possesses certain solubility in polar organic solvents, its behavior in water is notably limited. Understanding these solubility traits is crucial for applications in various fields including pharmaceuticals and material science.

Interesting facts

Interesting Facts about 5-chloro-2-methyl-1,3-benzothiazole

5-chloro-2-methyl-1,3-benzothiazole is a fascinating compound that belongs to the class of benzothiazoles. This group of compounds is known for their diverse biological activities and applications in various fields. Here are some intriguing aspects of this compound:

  • Biological Significance: Benzothiazole derivatives have demonstrated a range of biological properties, including antimicrobial, antifungal, and antitumor activities. The presence of chlorine and methyl groups can modify these properties significantly.
  • Pharmaceutical Applications: This compound and its derivatives are often explored in the pharmaceutical industry. Researchers examine their potential in drug development due to their ability to interact with various biological targets.
  • Synthesis: The synthesis of 5-chloro-2-methyl-1,3-benzothiazole is of great interest in organic chemistry. It often involves multi-step processes that demonstrate the principles of reaction mechanisms and functional group transformations.
  • Environmental Relevance: Similar compounds have been studied for their environmental impact, especially in relation to pollution and biodegradability. Understanding these effects is crucial in formulating regulations and developing sustainable practices.
  • Application in Materials Science: Beyond pharmaceuticals, benzothiazoles are utilized in the formulation of rubber and plastics, improving properties such as durability and resistance to aging.

As a compound that bridges the fields of chemistry, biology, and materials science, 5-chloro-2-methyl-1,3-benzothiazole serves as an excellent example of how specific molecular structures can lead to a wide array of applications and implications in both scientific research and industry. As stated by chemist Richard Feynman, “What I cannot create, I do not understand,” emphasizing the significance of understanding the underlying chemistry to create and manipulate such compounds for innovative solutions.

Synonyms
5-Chloro-2-methylbenzothiazole
1006-99-1
BENZOTHIAZOLE, 5-CHLORO-2-METHYL-
NSC 8453
EINECS 213-746-9
BRN 0120802
DTXSID0061402
4-27-00-01086 (Beilstein Handbook Reference)
DTXCID2032550
213-746-9
inchi=1/c8h6clns/c1-5-10-7-4-6(9)2-3-8(7)11-5/h2-4h,1h
xcalayirfyalsx-uhfffaoysa-n
5-chloro-2-methylbenzo[d]thiazole
5-Chloro-2-methyl-1,3-benzothiazole
2-methyl-5-chlorobenzothiazole
USAF EK-P-4382
5-Chloro-2-methyl-benzothiazole
MFCD00022881
2-Methyl-5-chloro-benzothiazole
2-methyl-5-chloro benzothiazole
NSC8453
Cambridge id 5107825
SCHEMBL1049510
WLN: T56 BN DSJ C1 HG
NSC-8453
STK396249
5-Chloro-2-methylbenzothiazole, 97%
AKOS000121462
5-Chloro-2-methyl-1,3-benzothiazole #
AC-15246
AS-12866
BP-12408
SY036182
DB-029121
CS-0037554
NS00022995
EN300-21184
AE-848/30689013
F9995-1151
Z104493618